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Results for "

2-o-methyl-

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Apoptosis (1) Bacterial (3) Biochemical Assay Reagents (15) Calcium Channel (1) CD38 (1) Cholecystokinin Receptor (1) CRFR (2) DNA/RNA Synthesis (7) Drug Derivative (2) Drug Intermediate (2) Dystrophin (1) Endogenous Metabolite (1) Ferroportin (1) Isotope-Labeled Compounds (5) MMP (1) Nucleoside Antimetabolite/Analog (40) Phosphoramidites (14) Reactive Oxygen Species (ROS) (1) TNF Receptor (1) Vasopressin Receptor (1) Virus Protease (1) Xanthine Oxidase (1)
By Research Areas:	Cancer (26) Cardiovascular Disease (1) Endocrinology (1) Infection (5) Inflammation/Immunology (4) Metabolic Disease (3) Neurological Disease (3)
Click Chemistry:	Azide (1)
Oligonucleotides:	Adenosine (2) Guanosine (3) saRNAs (1) Adenine (2) Antisense Oligonucleotides (1) Other Phosphoramidite (1) Cytidine (3) Guanine (2) Nucleoside Analogs (30) Uridine (16) Hypoxanthine (2) Inosine (1) Cytosine (1) Uracil (6) Phosphoramidites (14)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-134124

*Glutathione ethyl* ester**	Reactive Oxygen Species (ROS)	Metabolic Disease
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-138579

2'-OMe-G(ibu) Phosphoramidite DMT-2'-O-methyl-rG(ib) Phosphoramidite	Phosphoramidites Nucleoside Antimetabolite/Analog	Cancer
2'-OMe-G(ibu) Phosphoramidite (DMT-2'-O-Methyl-rG(ib) Phosphoramidite) is a modified phosphoramidite monomer that can be used for the oligonucleotide synthesis .

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis ^[2].

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment ^[2].

HY-W101391

*DMT-2'O-Methyl-rU Phosphoramidite* 2'-O-Me-U Phosphoramidite	Phosphoramidites DNA/RNA Synthesis	Others
DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis ^[2].

HY-145724

Drisapersen Kyndrisa; GSK2402968A; PRO051	DNA/RNA Synthesis Dystrophin	Neurological Disease
Drisapersen (Kyndrisa) is a 2 ^'-O-methyl phosphorothioate RNA antisense oligonucleotide that induces exon 51 skipping. Drisapersen induces skipping of exon 51 during Dystrophin pre-mRNA splicing, allowing the synthesis of partially functional Dystrophin. Drisapersen can be used in research related to Duchenne muscular dystrophy ^[2].

HY-P1108A

Astressin 2B TFA 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective *CRFR2* antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 ^[2] .

HY-P1108

Astressin 2B 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B is a blood-brain barrier-impermeable, highly selective *CRFR2* antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 ^[2] .

HY-W100234

*5-Methyl-2′-O-methyl-uridine* 2'-O-methyl-5-methyluridine	Nucleoside Antimetabolite/Analog	Cancer
5-Methyl-2’-O-methyl-uridine (2'-O-methyl-5-methyluridine) is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis. 5-Methyl-2’-O-methyl-uridine is a modified nucleoside that can be found in tRNA isolated from rabbit liver ^[2].

HY-P10143

MMP-2/MMP-9 Substrate Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt	MMP	Others
MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties ^[2].

HY-A0248AS

Polymyxin B1-d7 TFA	Isotope-Labeled Compounds Bacterial	Infection
Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment ^[2].

HY-157504

2′-O-Methyl-5′-O-phosphonoadenylyl-(3′→5′)-guanosine TEA	Nucleoside Antimetabolite/Analog	Others
2’-O-Methyl-5’-O-phosphonoadenylyl-(3’→5’)-guanosine (TEA) is a trinucleotide cap analogue that regulates protein expression in living cells .

HY-152693

*N4-Methyl-2’-O-methyl-cytidine* 1 Publications Verification	Nucleoside Antimetabolite/Analog	Others
N4-Methyl-2’-O-methyl-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-21286

N2-Isobutyryl-2'-O-methylguanosine	Drug Intermediate	Others
N2-Isobutyryl-2'-O-methylguanosine is a nucleic acid synthesis intermediate (e.g., used in antisense oligonucleotides, mRNA modification), for example, it is a key monomer for the synthesis of 2'-O-methyl oligoribonucleotides. N2-Isobutyryl-2'-O-methylguanosine enables the final product to form stable double strands with complementary RNA and is not easily degraded by nucleases. N2-Isobutyryl-2'-O-methylguanosine is mainly used in molecular biology research, and can be used to prepare RNA hybridization probes or participate in related biochemical research such as pre-mRNA splicing mechanisms .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-108987

*1-O-hexadecyl-2-O-methyl-sn-glycerol*	Biochemical Assay Reagents	Others
1-O-hexadecyl-2-O-methyl-sn-glycerol (PMG) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-152706

2’-O-Methyl-N2,N2-dimethyl-guanosine	Nucleoside Antimetabolite/Analog	Others
2’-O-Methyl-N2,N2-dimethyl-guanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W340190

2'-O-Methyl-5-iodouridine 5-Iodo-2'-O-methyluridine	Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Apoptosis	Cancer
2’-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154223

*5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine*	Nucleoside Antimetabolite/Analog Phosphoramidites	Cancer
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154490

*5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-uridine*	Nucleoside Antimetabolite/Analog	Cancer
5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154582

*5-Naphthyl-beta-methylaminocarbony-3’-O-acetyl-2’-O-methyl-5’-O-DMTr-uridine*	Nucleoside Antimetabolite/Analog	Others
5-Naphthyl-beta-methylaminocarbony-3’-O-acetyl-2’-O-methyl-5’-O-DMTr-uridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-154485

*5'-O-DMTr-2'-O-methyl-N6-methyl* adenosine 3'-CED phosphoramidite**	Nucleoside Antimetabolite/Analog Phosphoramidites	Cancer
5'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

HY-154380

*6-Chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-9H-purine*	Nucleoside Antimetabolite/Analog	Cancer
6-Chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W127608

2-Methoxy-3-octadecoxypropan-1-ol	Biochemical Assay Reagents	Others
1-O-Octadecyl-2-O-methyl-rac-glycerol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-134070

2-O-Methyl PAF C-16 ET-18-O-OCH3	TNF Receptor	Inflammation/Immunology
2-O-Methyl PAF C-16 (ET-18-O-OCH3), a structural analog of the mediator of inflammation platelet-activating factor (PAF), is a cytotoxic ether lipid. 2-O-Methyl PAF C-16 stimulates TNF-α release in murine macrophages .

HY-167925S

2'-O-Methyl Uridine-d3	Isotope-Labeled Compounds Calcium Channel Adrenergic Receptor	Endocrinology
2'-O-Methyl Uridine-d₃ is the deuterium labeled Rec 15/2615 (HY-167925). Rec 15/2615 is a potent α(1)-adrenergic agonist that stimulates small cholangiocyte proliferation through the activation of calcium-dependent signaling pathways.

HY-P3066

SKF 100398 d(CH2)5Tyr(Et)VAVP	Vasopressin Receptor	Metabolic Disease
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .

HY-W1119957

5'-VP-2'-OMe-U phosphoramidite	Biochemical Assay Reagents	Others
5'-VP-2'-OMe-U phosphoramidite is a phosphoramidite that contains 5’ DMT and uridine with 2’-O-methyl protection. 5'-VP-2'-OMe-U Phosphoramidite can be used to synthesize oligonucleotide.

HY-W091754

*5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine*	Nucleoside Antimetabolite/Analog Phosphoramidites	Others
5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside that is made using an oxime opening of the 5' position and a methylation at the 2' position. 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay.

HY-W744002

2'-O-Methyl-d3 Paclitaxel	Isotope-Labeled Compounds	Others
2'-O-Methyl-d₃ Paclitaxel is the deuterium labeled 2'-O-Methyl Paclitaxel (HY-W741186).

HY-154375

*5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine*	Nucleoside Antimetabolite/Analog	Cancer
5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W392836

2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite	Nucleoside Antimetabolite/Analog Xanthine Oxidase Phosphoramidites	Cancer
2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia ^[2].

HY-W753672

2'-O-Methyladenosine-d3	Isotope-Labeled Compounds	Cardiovascular Disease
2'-O-Methyl Adenosine-d₃ is deuterium labeled 2'-O-Methyl Adenosine. 2'-O-Methyl Adenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyl Adenosine exhibits unique hypotensive activities ^[2].

HY-P10828

MAPI	Virus Protease	Infection Inflammation/Immunology
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .

HY-21713

*DMT-2'O-Methyl-rC(tac) phosphoramidite*	DNA/RNA Synthesis Phosphoramidites	Others
DMT-2'O-Methyl-rC(tac) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-177371

CEBPA-51 saRNA	Nucleoside Antimetabolite/Analog	Cancer
CEBPA-51 saRNA, a double-stranded RNA oligo duplex to specifically upregulate the transcription of the CEBPA gene. CEBPA-51 saRNA contains multiple 2′-O-methyl modified bases to prevent nonspecific immunostimulatory activity .

HY-150017

2'-O-Methyl-5-methyl-U CEP	Drug Intermediate Phosphoramidites	Others
2'-O-Methyl-5-methyl-U CEP is a uridine, can be used for synthesis nucleic acid.

HY-152513

2’-O-Methyl-4-thiouridine	Nucleoside Antimetabolite/Analog	Others
2’-O-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152836

2’-O-Methyl-5-hydroxymethyluridine	Nucleoside Antimetabolite/Analog	Others
2’-O-Methyl-5-hydroxymethyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152717

2’-O-Methyl-2-thiouridine	Nucleoside Antimetabolite/Analog	Others
2’-O-Methyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152635

*8-Chloro-2’-O-methyl* adenosine**	Nucleoside Antimetabolite/Analog	Cancer
8-Chloro-2’-O-methyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152501

*8-Chloro-2’-O-methyl* inosine**	Nucleoside Antimetabolite/Analog	Cancer
8-Chloro-2’-O-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152466

2’-O-Methyl-N1-methyladenosine	Nucleoside Antimetabolite/Analog	Cancer
2’-O-Methyl-N1-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W776852

2-O-Methyl-β-neuraminic acid	Biochemical Assay Reagents	Others
2-O-Methyl-β-neuraminic acid is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-154317

2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium	Nucleoside Antimetabolite/Analog	Cancer
2’-O-Methyl-5-methyluridine 5’-triphosphate (triethylammonium) is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-157339

*MMT-2'-O-Methyl* adenosine (n-bz) CED phosphoramidite**	Nucleoside Antimetabolite/Analog Phosphoramidites	Others
MMT-2'-O-Methyl adenosine (n-bz) CED phosphoramidite (compound 1) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies .

HY-152518

2’-O-Methyl-5-methyl-4-thiouridine	Nucleoside Antimetabolite/Analog	Others
2’-O-Methyl-5-methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W342904

2’-O-Methyl-5’-O-DMTr-5-iodouridine 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-iodo-2'-O-methyl-uridine	Nucleoside Antimetabolite/Analog	Cancer
2’-O-Methyl-5’-O-DMTr-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154376

*4’,5’-Didehydro-2’-O-methyl-5-methyluridine*	Nucleoside Antimetabolite/Analog	Cancer
4’,5’-Didehydro-2’-O-methyl-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152796

*5-Furan-2-yl-2’-O-methyl* uridine**	Nucleoside Antimetabolite/Analog	Others
5-Furan-2-yl-2’-O-methyl uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

Cat. No.	Product Name	Type

HY-108987

*1-O-hexadecyl-2-O-methyl-sn-glycerol*	Biochemical Assay Reagents
1-O-hexadecyl-2-O-methyl-sn-glycerol (PMG) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127608

2-Methoxy-3-octadecoxypropan-1-ol	Biochemical Assay Reagents
1-O-Octadecyl-2-O-methyl-rac-glycerol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W776852

2-O-Methyl-β-neuraminic acid

Biochemical Assay Reagents

2-O-Methyl-β-neuraminic acid is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W698881

Methyl N-acetyl-2-O-methyl-β-neuraminate

Biochemical Assay Reagents

Methyl N-acetyl-2-O-methyl-β-neuraminate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W794623

Methyl 6-deoxy-2-O-methyl-α-D-galactopyranoside

Biochemical Assay Reagents

Methyl 6-deoxy-2-O-methyl-α-D-galactopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W700524

Methyl 6-deoxy-2-O-methyl-3-O-benzyl-α-D-galactopyranoside

Biochemical Assay Reagents

Methyl 6-deoxy-2-O-methyl-3-O-benzyl-α-D-galactopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W740309

Methyl 6-deoxy-2-O-methyl-3,4-O-(1-methylethylidene)-α-D-galactopyranoside

Biochemical Assay Reagents

Methyl 6-deoxy-2-O-methyl-3,4-O-(1-methylethylidene)-α-D-galactopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W777374

Methyl 2-O-methyl-3,4-O-(1-methylethylidene)-α-D-galactopyranoside	Biochemical Assay Reagents
Dodecyldimethylphosphine oxide is a biochemical assay reagent.

HY-W436265

O-Methyl-N-acetyl-2-deoxy-α-D-galactosamine

O-methyl-N-acetyl-2-deoxy-a-D-galactosamine

Biochemical Assay Reagents

O-Methyl-N-acetyl-2-deoxy-α-D-galactosamine (O-Methyl-N-acetyl-2-deoxy-a-D-galactosamine) is a class of biochemical reagents used in the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .

HY-134080

1-O-Hexadecyl-2-O-methylglycerol 1-O-Hexadecyl-2-O-methyl-rac-glycerol	Biochemical Assay Reagents
1-O-Hexadecyl-2-O-methylglycerol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-167813

1-O-Palmityl-2-O-methyl-rac-glycero-3-phosphocholine

Biochemical Assay Reagents

1-O-Palmityl-2-O-methyl-rac-glycero-3-phosphocholine is a synthetic phospholipid analogue with activity in studying lipid interactions and membrane asymmetry. 1-O-Palmityl-2-O-methyl-rac-glycero-3-phosphocholine is used to explore the overall stability of lipid bilayers. 1-O-Palmityl-2-O-methyl-rac-glycero-3-phosphocholine is of great significance for the study of membrane structure and function.

HY-W698718

N-Acetyl-2-O-methyl-β-neuraminic acid

Biochemical Assay Reagents

N-Acetyl-2-O-methyl-β-neuraminic acid is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W700861

N-Acetyl-2-O-methyl-α-neuraminic acid methyl ester 4,7,8,9-tetraacetate

Biochemical Assay Reagents

N-Acetyl-2-O-methyl-α-neuraminic acid methyl ester 4,7,8,9-tetraacetateis a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W777372

Methyl 4-azido-4,6-dideoxy-2-O-methyl-3-O-(phenylmethyl)-α-D-glucopyranoside

Biochemical Assay Reagents

Methyl 4-azido-4,6-dideoxy-2-O-methyl-3-O-(phenylmethyl)-α-D-glucopyranoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

Cat. No.	Product Name	Target	Research Area

HY-134124

*Glutathione ethyl* ester**	Reactive Oxygen Species (ROS)	Metabolic Disease
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis ^[2].

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment ^[2].

HY-P1108A

Astressin 2B TFA 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective *CRFR2* antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 ^[2] .

HY-P1108

Astressin 2B 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B is a blood-brain barrier-impermeable, highly selective *CRFR2* antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 ^[2] .

HY-P10143

MMP-2/MMP-9 Substrate Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt	MMP	Others
MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties ^[2].

HY-A0248AS

Polymyxin B1-d7 TFA	Isotope-Labeled Compounds Bacterial	Infection
Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment ^[2].

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-P3066

SKF 100398 d(CH2)5Tyr(Et)VAVP	Vasopressin Receptor	Metabolic Disease
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .

HY-P10828

MAPI	Virus Protease	Infection Inflammation/Immunology
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .

HY-P4756

*N-(2-Carbamoyl-ethyl)-Val-Leu-anilide*	Peptides	Others
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P2592

Ro 23-7014	Cholecystokinin Receptor	Others
Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .

HY-125628

Kahalalide A	Endogenous Metabolite	Infection
Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .

HY-A0248AS1

Polymyxin B1-D-Leu-d7 TFA	Isotope-Labeled Compounds Bacterial	Infection
Polymyxin B1-D-Leu-d₇ TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment ^[2].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-A0248A

Polymyxin B1 1 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment ^[2].

HY-A0248AS

Polymyxin B1-d7 TFA	Structural Classification Microorganisms Antibiotics Antibacterial Disease Research Other Antibiotics Source Classification	Isotope-Labeled Compounds Bacterial
Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment ^[2].

HY-N17786

2-O-Methyl-D-xylose	Larix laricina (Du Roi) K.Koch Structural Classification Natural Products Pinaceae Plants Source Classification	Drug Derivative
2-O-Methyl-D-xylose is a derivative of Xylose (HY-N0537). 2-O-Methyl-D-xylose can be used as a biomarker for the cell wall polysaccharide RG-II, and changes in its content reveal the destructive effect of gene silencing on the cell wall structure .

HY-N17785

2-O-Methyl-L-fucose	Structural Classification Natural Products Taxus cuspidata Siebold & Zucc. Taxaceae Plants Source Classification	Drug Derivative
2-Methyl-2-O-methyl-L-fucose, a derivative of L-fucose (HY-W854443), is a natural sugar that can be found in Taxus cuspidata .

HY-A0248AS1

Polymyxin B1-D-Leu-d7 TFA	Structural Classification Microorganisms Antibiotics Antibacterial Disease Research Other Antibiotics Source Classification	Isotope-Labeled Compounds Bacterial
Polymyxin B1-D-Leu-d₇ TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment ^[2].

Cat. No.	Product Name	Chemical Structure

HY-A0248AS

Polymyxin B1-d7 TFA

Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment ^[2].

HY-167925S

2'-O-Methyl Uridine-d3
2'-O-Methyl Uridine-d₃ is the deuterium labeled Rec 15/2615 (HY-167925). Rec 15/2615 is a potent α(1)-adrenergic agonist that stimulates small cholangiocyte proliferation through the activation of calcium-dependent signaling pathways.

HY-W744002

2'-O-Methyl-d3 Paclitaxel
2'-O-Methyl-d₃ Paclitaxel is the deuterium labeled 2'-O-Methyl Paclitaxel (HY-W741186).

HY-W753672

2'-O-Methyladenosine-d3
2'-O-Methyl Adenosine-d₃ is deuterium labeled 2'-O-Methyl Adenosine. 2'-O-Methyl Adenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyl Adenosine exhibits unique hypotensive activities ^[2].

HY-A0248AS1

Polymyxin B1-D-Leu-d7 TFA

Polymyxin B1-D-Leu-d₇ TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment ^[2].

Cat. No.	Product Name		Classification

HY-154377

*5'-Azido-5'-deoxy-2'-O-methyl-5-methyluridine*		Azide
5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 5'-Azido-5'-deoxy-2'-O-methyl-5-methyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-138579

2'-OMe-G(ibu) Phosphoramidite DMT-2'-O-methyl-rG(ib) Phosphoramidite		Phosphoramidites Guanine
2'-OMe-G(ibu) Phosphoramidite (DMT-2'-O-Methyl-rG(ib) Phosphoramidite) is a modified phosphoramidite monomer that can be used for the oligonucleotide synthesis .

HY-W101391

*DMT-2'O-Methyl-rU Phosphoramidite* 2'-O-Me-U Phosphoramidite		Phosphoramidites Uracil
DMT-2'O-Methyl-rU Phosphoramidite (2'-O-Me-U Phosphoramidite) is a 2'-O-Me derivative, and can be used for oligonucleotide synthesis ^[2].

HY-145724

Drisapersen Kyndrisa; GSK2402968A; PRO051		Antisense Oligonucleotides
Drisapersen (Kyndrisa) is a 2 ^'-O-methyl phosphorothioate RNA antisense oligonucleotide that induces exon 51 skipping. Drisapersen induces skipping of exon 51 during Dystrophin pre-mRNA splicing, allowing the synthesis of partially functional Dystrophin. Drisapersen can be used in research related to Duchenne muscular dystrophy ^[2].

HY-145998

2′-O-Methyl-8-methyl guanosine m8Gm		Nucleoside Analogs Guanosine
2′-O-Methyl-8-methyl guanosine (m8Gm) is a Z-form RNA stabilizer. 2′-O-Methyl-8-methyl guanosine can markedly stabilize the Z-RNA at low salt conditions . m8Gm-contained oligonucleotides stabilize the Z-DNA under low salt conditions ^[2].

HY-W100234

*5-Methyl-2′-O-methyl-uridine* 2'-O-methyl-5-methyluridine		Nucleoside Analogs Uridine
5-Methyl-2’-O-methyl-uridine (2'-O-methyl-5-methyluridine) is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis. 5-Methyl-2’-O-methyl-uridine is a modified nucleoside that can be found in tRNA isolated from rabbit liver ^[2].

HY-152693

*N4-Methyl-2’-O-methyl-cytidine* 1 Publications Verification		Nucleoside Analogs Cytidine
N4-Methyl-2’-O-methyl-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-21286

N2-Isobutyryl-2'-O-methylguanosine		Nucleoside Analogs Guanosine
N2-Isobutyryl-2'-O-methylguanosine is a nucleic acid synthesis intermediate (e.g., used in antisense oligonucleotides, mRNA modification), for example, it is a key monomer for the synthesis of 2'-O-methyl oligoribonucleotides. N2-Isobutyryl-2'-O-methylguanosine enables the final product to form stable double strands with complementary RNA and is not easily degraded by nucleases. N2-Isobutyryl-2'-O-methylguanosine is mainly used in molecular biology research, and can be used to prepare RNA hybridization probes or participate in related biochemical research such as pre-mRNA splicing mechanisms .

HY-152706

2’-O-Methyl-N2,N2-dimethyl-guanosine		Nucleoside Analogs Guanosine
2’-O-Methyl-N2,N2-dimethyl-guanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154223

*5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine*		Phosphoramidites Uracil
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154490

*5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-uridine*		Nucleoside Analogs Uridine
5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154582

*5-Naphthyl-beta-methylaminocarbony-3’-O-acetyl-2’-O-methyl-5’-O-DMTr-uridine*		Nucleoside Analogs Uridine
5-Naphthyl-beta-methylaminocarbony-3’-O-acetyl-2’-O-methyl-5’-O-DMTr-uridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-154485

*5'-O-DMTr-2'-O-methyl-N6-methyl* adenosine 3'-CED phosphoramidite**		Phosphoramidites Adenine
5'-O-DMTr-2'-O-methyl-N6-methyl adenosine 3'-CED phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

HY-154380

*6-Chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-9H-purine*		Nucleoside Analogs
6-Chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W091754

*5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine*		Phosphoramidites Guanine
5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside that is made using an oxime opening of the 5' position and a methylation at the 2' position. 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay.

HY-154375

*5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine*		Nucleoside Analogs Uridine
5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W392836

2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite		Phosphoramidites Hypoxanthine
2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia ^[2].

HY-21713

*DMT-2'O-Methyl-rC(tac) phosphoramidite*		Phosphoramidites Cytosine
DMT-2'O-Methyl-rC(tac) Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-177371

CEBPA-51 saRNA		saRNAs
CEBPA-51 saRNA, a double-stranded RNA oligo duplex to specifically upregulate the transcription of the CEBPA gene. CEBPA-51 saRNA contains multiple 2′-O-methyl modified bases to prevent nonspecific immunostimulatory activity .

HY-150017

2'-O-Methyl-5-methyl-U CEP		Phosphoramidites Uracil
2'-O-Methyl-5-methyl-U CEP is a uridine, can be used for synthesis nucleic acid.

HY-152513

2’-O-Methyl-4-thiouridine		Nucleoside Analogs Uridine
2’-O-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152836

2’-O-Methyl-5-hydroxymethyluridine		Nucleoside Analogs Uridine
2’-O-Methyl-5-hydroxymethyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152717

2’-O-Methyl-2-thiouridine		Nucleoside Analogs Uridine
2’-O-Methyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152635

*8-Chloro-2’-O-methyl* adenosine**		Nucleoside Analogs Adenosine
8-Chloro-2’-O-methyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152501

*8-Chloro-2’-O-methyl* inosine**		Nucleoside Analogs Inosine
8-Chloro-2’-O-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152466

2’-O-Methyl-N1-methyladenosine		Nucleoside Analogs Adenosine
2’-O-Methyl-N1-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154317

2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium		Nucleoside Analogs Uridine
2’-O-Methyl-5-methyluridine 5’-triphosphate (triethylammonium) is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-157339

*MMT-2'-O-Methyl* adenosine (n-bz) CED phosphoramidite**		Phosphoramidites Adenine
MMT-2'-O-Methyl adenosine (n-bz) CED phosphoramidite (compound 1) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies .

HY-152518

2’-O-Methyl-5-methyl-4-thiouridine		Nucleoside Analogs Uridine
2’-O-Methyl-5-methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W342904

2’-O-Methyl-5’-O-DMTr-5-iodouridine 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-iodo-2'-O-methyl-uridine		Nucleoside Analogs Uridine
2’-O-Methyl-5’-O-DMTr-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154376

*4’,5’-Didehydro-2’-O-methyl-5-methyluridine*		Nucleoside Analogs Uridine
4’,5’-Didehydro-2’-O-methyl-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152796

*5-Furan-2-yl-2’-O-methyl* uridine**		Nucleoside Analogs Uridine
5-Furan-2-yl-2’-O-methyl uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154377

*5'-Azido-5'-deoxy-2'-O-methyl-5-methyluridine*		Nucleoside Analogs Uridine
5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 5'-Azido-5'-deoxy-2'-O-methyl-5-methyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152876

2′-O-Methyl-2-amino-6-chloropurine riboside		Nucleoside Analogs
6-Chloro-9-(2-O-methyl-beta-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152660

*2-Amino-6-O-methyl-2’-O-methyl* purine riboside**		Nucleoside Analogs
2-Amino-6-O-methyl-2’-O-methyl purine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154588

*1-[6-Phosphono-2-O-methyl-β-D-ribo-hexofuranosyl]uracil*		Nucleoside Analogs Uridine
1-[6-Phosphono-2-O-methyl-β-D-ribo-hexofuranosyl]uracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154587

*1-[6-(Diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hexofuranosyl]uracil*		Nucleoside Analogs Uridine
1-[6-(Diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hexofuranosyl]uracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154000

*3,5’-Bis(O-t-butyldimethylsilyl)-2’-O-methyl-5-methyl* cytidine**		Nucleoside Analogs Cytidine
3,5’-Bis(O-t-butyldimethylsilyl)-2’-O-methyl-5-methyl cytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .

HY-154581

*5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-cytidine*		Nucleoside Analogs Cytidine
5-(Furan-2-yl)-2’-O-methyl-5’-O-DMTr-cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154684

*5-Benzylamino carbonyl-3’-O-acetyl-2’-O-methyl-5’-O-DMTr-uridine*		Nucleoside Analogs Uridine
5-Benzylamino carbonyl-3’-O-acetyl-2’-O-methyl-5’-O-DMTr-uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-154379

*3',5'-Di-O-acetyl-2'-O-methyl-6-chloro-2-aminopurine riboside*		Nucleoside Analogs
3',5'-Di-O-acetyl-2'-O-methyl-6-chloro-2-aminopurine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-W395015

*5’-O-(4,4-Dimethoxytrityl)-2’-O-methyl* inosine** 5'-O-(DIMETHOXYTRITYL)-2'-O-methylINOSINE		Phosphoramidites Hypoxanthine
5’-O-(4,4-Dimethoxytrityl)-2’-O-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-152770

*6-(2-O-Methyl-beta-D-ribofuranosyl)-3-(2-oxo-propyl)-6H-imidazo[1,2-c]pyrimidin-5-one*		Nucleoside Analogs
6-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-3-(2-oxopropyl)imidazo[1,2-c]pyrimidin-5(6H)-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-200316

*DMTr-2'-O-Methyl* palmitate-rU-3'-CE-phosphoramidite**		Phosphoramidites Uracil
DMTr-2'-O-(Methyl palmitate)-rU-3'-CE-phosphoramidite is a monomeric raw material that can be used for nucleic acid synthesis.

HY-W714955

2'-O-Methyl-pyrrolo C CEP		Phosphoramidites Other Phosphoramidite
(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxy-5-(6-methyl-2-oxo-2,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-3-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-200336

2'-OMe 5-Br-U Amidite		Phosphoramidites Uracil
Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-5-bromo-2′-O-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a phosphoramidite that can be used in the synthesis of oligonucleotides.

HY-200335

5'-O-DMTr-2'-OMe-5-Iodouridine-3'-CEN-phosphoramidite		Phosphoramidites Uracil
Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-5-iodo-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a phosphoramidite that can be used in the synthesis of oligonucleotides.

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