2'-O-Methyl-5-iodouridine
Based on 1 Customer Validation
2’-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 99.63%
- CAS No.: 34218-84-3
- Formula: C10H13IN2O6
- Molecular Weight:384.12
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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CAS No. 34218-84-3
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Appearance Solid
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Molecular Weight 384.12
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Formula C10H13IN2O6
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Color White to light yellow
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SMILES
O[C@H]1[C@@H](OC)[C@H](N2C(NC(C(I)=C2)=O)=O)O[C@@H]1CO
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Synonyms
5-Iodo-2'-O-methyluridine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (325.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6034 mL | 13.0168 mL | 26.0335 mL | 65.0838 mL |
| 5 mM | 0.5207 mL | 2.6034 mL | 5.2067 mL | 13.0168 mL | |
| 10 mM | 0.2603 mL | 1.3017 mL | 2.6034 mL | 6.5084 mL | |
| 15 mM | 0.1736 mL | 0.8678 mL | 1.7356 mL | 4.3389 mL | |
| 20 mM | 0.1302 mL | 0.6508 mL | 1.3017 mL | 3.2542 mL | |
| 25 mM | 0.1041 mL | 0.5207 mL | 1.0413 mL | 2.6034 mL | |
| 30 mM | 0.0868 mL | 0.4339 mL | 0.8678 mL | 2.1695 mL | |
| 40 mM | 0.0651 mL | 0.3254 mL | 0.6508 mL | 1.6271 mL | |
| 50 mM | 0.0521 mL | 0.2603 mL | 0.5207 mL | 1.3017 mL | |
| 60 mM | 0.0434 mL | 0.2169 mL | 0.4339 mL | 1.0847 mL | |
| 80 mM | 0.0325 mL | 0.1627 mL | 0.3254 mL | 0.8135 mL | |
| 100 mM | 0.0260 mL | 0.1302 mL | 0.2603 mL | 0.6508 mL |