2. Cell Cycle/DNA Damage Apoptosis
  3. Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Apoptosis
  4. 2'-O-Methyl-5-iodouridine

2'-O-Methyl-5-iodouridine  (Synonyms: 5-Iodo-2'-O-methyluridine)

Cat. No.: HY-W340190 Pureza: 99.63%
COA
SDS
Instrucciones de manejo Technical Support

2’-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

Para uso exclusivo en investigación. No vendemos a pacientes.

2'-O-Methyl-5-iodouridine

2'-O-Methyl-5-iodouridine Estructura química

No. CAS : 34218-84-3

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
25 mg En stock
50 mg En stock
100 mg En stock
200 mg   Obtener un presupuesto  
500 mg   Obtener un presupuesto  

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Revisión del cliente

Based on 1 Customer Validation

2'-O-Methyl-5-iodouridine Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas DNA/RNA Synthesis:

Ver todas las isoformas
RNASE L DNA Polymerases RNA Polymerases Helicases DNA Ligase

  • Actividad biológica

  • Pureza y Documentación

  • Referencias

  • Revisión del cliente

Descripciòn

2’-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Peso molecular

384.12

Fòrmula

C10H13IN2O6
No. CAS
Appearance

Solid

Color

White to light yellow

SMILES

O[C@H]1[C@@H](OC)[C@H](N2C(NC(C(I)=C2)=O)=O)O[C@@H]1CO
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 125 mg/mL (325.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6034 mL 13.0168 mL 26.0335 mL
5 mM 0.5207 mL 2.6034 mL 5.2067 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6034 mL 13.0168 mL 26.0335 mL 65.0838 mL
5 mM 0.5207 mL 2.6034 mL 5.2067 mL 13.0168 mL
10 mM 0.2603 mL 1.3017 mL 2.6034 mL 6.5084 mL
15 mM 0.1736 mL 0.8678 mL 1.7356 mL 4.3389 mL
20 mM 0.1302 mL 0.6508 mL 1.3017 mL 3.2542 mL
25 mM 0.1041 mL 0.5207 mL 1.0413 mL 2.6034 mL
30 mM 0.0868 mL 0.4339 mL 0.8678 mL 2.1695 mL
40 mM 0.0651 mL 0.3254 mL 0.6508 mL 1.6271 mL
50 mM 0.0521 mL 0.2603 mL 0.5207 mL 1.3017 mL
60 mM 0.0434 mL 0.2169 mL 0.4339 mL 1.0847 mL
80 mM 0.0325 mL 0.1627 mL 0.3254 mL 0.8135 mL
100 mM 0.0260 mL 0.1302 mL 0.2603 mL 0.6508 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

2'-O-Methyl-5-iodouridine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2'-O-Methyl-5-iodouridine34218-84-35-Iodo-2'-O-methyluridineNucleoside Antimetabolite/AnalogDNA/RNA SynthesisApoptosisindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

Productos vistos recientemente:

Consulta en línea

Your information is safe with us. * Required Fields.

Nombre del producto

  

Requested Quantity *

Nombre del solicitante *

 

Saludo

Direcciòn del E-mail *

 

Número de teléfono *

Department

 

Nombre de la Organizaciòn *

City

Provincia

Country or Region *

      

Observaciones

Consulta para venta a granel

Inquiry Information

Nombre del producto:
2'-O-Methyl-5-iodouridine
Cat. No.:
HY-W340190
Cantidad:
MCE Japan Authorized Agent:

Revisión del cliente

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Nombre del producto

  

Lot #

Nombre del solicitante *

 

Direcciòn del E-mail *

Número de teléfono

 

Department *

Nombre de la Organizaciòn *

 

Country or Region *

Observaciones

SAFETY DATA SHEET (SDS)

English - EN (394 KB) Français - FR (394 KB) Deutsch - DE (394 KB) Norwegian - NO (394 KB) Español - ES (394 KB) Swedish - SV (394 KB) Italian - IT (394 KB) Korean - KR (394 KB) Portuguese - PT (394 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.