1. Natural Products
  2. Endogenous metabolite
  3. Disease markers
  4. Endocrine diseases

Endocrine diseases

Endocrine diseases (135):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-18085
    Quercetin 117-39-5 98.03%
    Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively.
  • HY-B0141
    Estradiol 50-28-2 99.99%
    Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering.
  • HY-N0287
    Lycopene 502-65-8 ≥98.0%
    Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects.
  • HY-B0166
    L-Ascorbic acid 50-81-7 99.92%
    L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells.
    L-Ascorbic acid
  • HY-A0070A
    Liothyronine 6893-02-3 99.82%
    Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively.
  • HY-B0399
    L-Carnitine 541-15-1 ≥98.0%
    L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism.
  • HY-126585
    SAICAR 3031-95-6 99.66%
    SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner, with an EC50 of 0.3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose-limited conditions.
  • HY-16637
    Folic acid 59-30-3 99.56%
    Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency.
    Folic acid
  • HY-N1446
    Oleic acid 112-80-1 ≥98.0%
    Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator.
    Oleic acid
  • HY-N0729
    Linoleic acid 60-33-3 98.57%
    Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .
    Linoleic acid
  • HY-W040193
    DSPC 816-94-4 ≥98.0%
    DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system.
  • HY-12033
    2-Methoxyestradiol 362-07-2 99.82%
    2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa.
  • HY-W010040
    4-​Hydroxyphenylpyruvic acid 156-39-8
    4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of the amino acid phenylalanine.
    4-​Hydroxyphenylpyruvic acid
  • HY-17563
    2'-Deoxyguanosine 961-07-9 99.70%
    2'-Deoxyguanosine (Deoxyguanosine) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
  • HY-B0141A
    Alpha-Estradiol 57-91-0 99.86%
    Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.
  • HY-101406
    Thyroxine sulfate 77074-49-8 99.84%
    Thyroxine sulfate is a thyroid hormone metabolite.
    Thyroxine sulfate
  • HY-B2235
    Lecithin 8002-43-5 ≥98.0%
    Lecithin is regarded as a safe, conventional phospholipid source. Phospholipids are reported to alter the fatty acid composition and microstructure of the membranes in animal cells.
  • HY-113008
    Urocanic acid 104-98-3 99.73%
    Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR).
    Urocanic acid
  • HY-W012980
    Isovaleric acid 503-74-2 ≥98.0%
    Isovaleric acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human.
    Isovaleric acid
  • HY-113411
    3-Hydroxyglutaric acid 638-18-6 99.89%
    3-Hydroxyglutaric acid is a glutaric acid derivative.
    3-Hydroxyglutaric acid