1. Others Anti-infection
  2. Isotope-Labeled Compounds Antibiotic Parasite Bacterial
  3. Dimetridazole-d3

Dimetridazole-d3  (Synonyms: 1,2-Dimethyl-5-nitroimidazole-d3; ジメトリダゾール-d3)

製品番号: HY-B1244S 純度: 99.78%
COA 取扱説明書 Technical Support

Dimetridazole-d3 (1,2-Dimethyl-5-nitroimidazole-d3) is a deuterium labeled Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Dimetridazole-d<sub>3</sub>

Dimetridazole-d3 構造式

CAS 番号 : 64678-69-9

容量 価格(税別) 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 165 お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
Solution
10 mM * 1 mL in DMSO USD 165 お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
Solid
1 mg $50 お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
5 mg $150 在庫あり
10 mg $250 在庫あり
50 mg   お問い合わせ  
100 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

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カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of Dimetridazole-d3:

Top Publications Citing Use of Products
  • 生物活性

  • 純度とドキュメンテーション

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製品説明

Dimetridazole-d3 (1,2-Dimethyl-5-nitroimidazole-d3) is a deuterium labeled Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections[1][2][3][4].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

144.15

分子式

C5H4D3N3O2

CAS 番号
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=[N+](C1=CN=C(C)N1C([2H])([2H])[2H])[O-]

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 50 mg/mL (346.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.9372 mL 34.6861 mL 69.3722 mL
5 mM 1.3874 mL 6.9372 mL 13.8744 mL
10 mM 0.6937 mL 3.4686 mL 6.9372 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

C1

×
体積 (開始)

V1

=
濃度 (終了)

C2

×
体積 (終了)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.9372 mL 34.6861 mL 69.3722 mL 173.4305 mL
5 mM 1.3874 mL 6.9372 mL 13.8744 mL 34.6861 mL
10 mM 0.6937 mL 3.4686 mL 6.9372 mL 17.3430 mL
15 mM 0.4625 mL 2.3124 mL 4.6248 mL 11.5620 mL
20 mM 0.3469 mL 1.7343 mL 3.4686 mL 8.6715 mL
25 mM 0.2775 mL 1.3874 mL 2.7749 mL 6.9372 mL
30 mM 0.2312 mL 1.1562 mL 2.3124 mL 5.7810 mL
40 mM 0.1734 mL 0.8672 mL 1.7343 mL 4.3358 mL
50 mM 0.1387 mL 0.6937 mL 1.3874 mL 3.4686 mL
60 mM 0.1156 mL 0.5781 mL 1.1562 mL 2.8905 mL
80 mM 0.0867 mL 0.4336 mL 0.8672 mL 2.1679 mL
100 mM 0.0694 mL 0.3469 mL 0.6937 mL 1.7343 mL
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
Dimetridazole-d3
製品番号:
HY-B1244S
数量:
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