551-92-8
551-92-8
Chemical Structure
Dimetridazole
Synonym(s): 1,2-Dimethyl-5-nitroimidazole
- CAS 番号: 551-92-8
- Formula:C5H7N3O2
- Molecular Weight:141.13
IUPAC Name: 1,2-dimethyl-5-nitro-1H-imidazole
InChIKey: IBXPYPUJPLLOIN-UHFFFAOYSA-N
SMILES: O=[N+](C1=CN=C(C)N1C)[O-]
Biological Activity: Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections[1][2][3][4].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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Dimetridazole | 98.0% | Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections. | ||||||||||||||||||||
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Dimetridazole (Standard) | ≥98% | Dimetridazole (Standard) is the analytical standard of Dimetridazole (HY-B1244). This product is intended for research and analytical applications. Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections. | ||||||||||||||||||||
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Dimetridazole-d3 | 99.78% | Dimetridazole-d3 (1,2-Dimethyl-5-nitroimidazole-d3) is a deuterium labeled Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections. | ||||||||||||||||||||
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References
- [1]. Zaghdoudi M, et al. Direct and indirect electrochemical reduction prior to a biological treatment for dimetridazoleremoval. J Hazard Mater. 2017 Aug 5;335:10-17. [Content Brief]
- [2]. Fernie DS, et al. The effect of the nitroimidazole drug dimetridazole on microaerophilic campylobacters. J Med Microbiol. 1977 May;10(2):233-40. [Content Brief]
- [3]. Jokipii L, et al. Comparative evaluation of the 2-methyl-5-nitroimidazole compounds dimetridazole, metronidazole, secnidazole, ornidazole, tinidazole, carnidazole, and panidazole against Bacteroides fragilis and other bacteria of the Bacteroides fragilis group. Antimicrob Agents Chemother. 1985 Oct;28(4):561-4. [Content Brief]
- [4]. Ré JL, et al. Evaluation of the genotoxic activity of metronidazole and dimetridazole in human lymphocytes by the comet assay. Mutat Res. 1997 Apr 29;375(2):147-55. [Content Brief]
