1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. TRP Channel
    Calcium Channel
  3. Hyperforin dicyclohexylammonium salt

Hyperforin dicyclohexylammonium salt (Synonyms: Hyperforin DCHA)

Cat. No.: HY-116330A Purity: 98.17%
Handling Instructions

Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin dicyclohexylammonium salt modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt shows antidepressant effect.

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Hyperforin dicyclohexylammonium salt Chemical Structure

Hyperforin dicyclohexylammonium salt Chemical Structure

CAS No. : 238074-03-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 1580 In-stock
Estimated Time of Arrival: December 31
500 μg USD 120 In-stock
Estimated Time of Arrival: December 31
1 mg USD 200 In-stock
Estimated Time of Arrival: December 31
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Description

Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin dicyclohexylammonium salt modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt shows antidepressant effect[1][2].

In Vitro

Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) has a multi-directional mechanism of action. It blocks conductance of ligand-gated (GABA, NMDA, and AMPA receptors) and voltage-gated channels (Ca2+, K+, and Na+)[2].

Molecular Weight

718.10

Formula

C₄₇H₇₅NO₄

CAS No.

238074-03-8

SMILES

CC(C)C([[email protected]@]12[[email protected]@](C)([[email protected]](C[[email protected]](C/C=C(C)/C)(C(C(C/C=C(C)/C)=C2O)=O)C1=O)C/C=C(C)/C)CC/C=C(C)/C)=O.C3(CCCCC3)NC4CCCCC4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (69.63 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3926 mL 6.9628 mL 13.9256 mL
5 mM 0.2785 mL 1.3926 mL 2.7851 mL
10 mM 0.1393 mL 0.6963 mL 1.3926 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (3.48 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

Hyperforin dicyclohexylammoniumHyperforin DCHATRP ChannelCalcium ChannelTransient receptor potential channelsCa2+ channelsCa channelsantidepressantchannelmodulatecanonicalmulti-directionalGABANMDAAMPAreceptorsvoltage-gatedInhibitorinhibitorinhibit

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Product Name:
Hyperforin dicyclohexylammonium salt
Cat. No.:
HY-116330A
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