MMP-2/MMP-9-IN-1

Art. -Nr.: HY-116399 Reinheit: 99.48%: Data Sheet
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MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase (MMP-9 and MMP-2) inhibitor with IC₅₀s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer.

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MMP-2/MMP-9-IN-1 Chemische Struktur

CAS. Nr. : 193807-58-8

Größe	Verfügbarkeit	Menge
5 mg	Auf Lager	Estimated Time of Arrival: December 31
10 mg	Auf Lager	Estimated Time of Arrival: December 31
25 mg	Auf Lager	Estimated Time of Arrival: December 31
50 mg	Auf Lager	Estimated Time of Arrival: December 31
100 mg	Auf Lager	Estimated Time of Arrival: December 31
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Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Alle MMP Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8 MMP-19

Biologische Aktivität
Reinheit & Dokumentation
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Beschreibung	MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase (MMP-9 and MMP-2) inhibitor with IC₅₀s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer^[1].
Molekulargewicht	381.44
Formel	C₂₁H₁₉NO₄S
CAS. Nr.	193807-58-8
Appearance	Solid
Color	White to off-white
SMILES	OC([C@@H](CC1=CC=CC=C1)NS(C2=CC=C(C3=CC=CC=C3)C=C2)(=O)=O)=O
Versand	Room temperature in continental US; may vary elsewhere.
Speicherung	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reinheit & Dokumentation	Purity: 99.48% Select Batch: Data Sheet (270 KB) SDS (252 KB) COA (251 KB) HNMR (266 KB) LCMS (99 KB) Handling Instructions (2659 KB)
Verweise	[1]. Y Tamura, et al. Highly selective and orally active inhibitors of type IV collagenase (MMP-9 and MMP-2): N-sulfonylamino acid derivatives. J Med Chem. 1998 Feb 12;41(4):640-9. [Content Brief]

MMP-2/MMP-9-IN-1 Related Classifications

Molaritätsrechner
Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Diese Gleichung wird häufig abgekürzt als: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MMP-2/MMP-9-IN-1193807-58-8MMPMatrix metalloproteinasestype IV collagenaseMMP-9 and MMP-2orally activetumor growth and metastasiscancerInhibitorinhibitorinhibit

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MMP-2/MMP-9-IN-1

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MMP-2/MMP-9-IN-1 Related Antibodies

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Alle MMP Isoform-spezifische Produkte anzeigen:

Biologische Aktivität

Reinheit & Dokumentation

Verweise

Kundenbewertung

MMP-2/MMP-9-IN-1 Related Classifications

Molaritätsrechner

Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

The dilution calculator equation

Keywords:

Ihre kürzlich angesehenen Produkte:

Kundenbewertung

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