1. Anti-infection Apoptosis
  2. Bacterial Apoptosis
  3. Neogambogic acid

Neogambogic acid 

Cat. No.: HY-N2058
Handling Instructions

Neogambogic acid, an active ingredient in garcinia, induces apoptosis and has anticancer effect. Neogambogic acid has significant inhibitory activity toward methicillin-resistant Staphylococcus aureus (MRSA).

For research use only. We do not sell to patients.

Neogambogic acid Chemical Structure

Neogambogic acid Chemical Structure

CAS No. : 93772-31-7

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Description

Neogambogic acid, an active ingredient in garcinia, induces apoptosis and has anticancer effect. Neogambogic acid has significant inhibitory activity toward methicillin-resistant Staphylococcus aureus (MRSA)[1][2].

In Vitro

Neogambogic acid inhibits HCT-8, Bel-7402, BGC-823, A549, and A2780 cell proliferation, with an IC50 between 1.75 and 3 μM. Neogambogic acid induces A549 cells apoptosis arrested the cells to G0/G1 phase in vitro[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Neogambogic acid arrests A549-induced tumor growth in nude mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

646.77

Formula

C38H46O9

CAS No.
SMILES

C/C(C(O)=O)=C/C[C@@]1(OC(C)(C)[C@]2([H])C3)[C@@]2(OC4=C(C(O[C@@](CC/C=C(C)/C)(C)C5)=C6C5O)C/C=C(C)/C)C(C(C4=C6O)=O)=C[C@@]3([H])C1=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Neogambogic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Neogambogic acid
Cat. No.:
HY-N2058
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