1. Anti-infection
    Apoptosis
  2. Bacterial
    Apoptosis
  3. Neogambogic acid

Neogambogic acid 

Cat. No.: HY-N2058
Handling Instructions

Neogambogic acid, an active ingredient in garcinia, induces apoptosis and has anticancer effect. Neogambogic acid has significant inhibitory activity toward methicillin-resistant Staphylococcus aureus (MRSA).

For research use only. We do not sell to patients.

Neogambogic acid Chemical Structure

Neogambogic acid Chemical Structure

CAS No. : 93772-31-7

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Description

Neogambogic acid, an active ingredient in garcinia, induces apoptosis and has anticancer effect. Neogambogic acid has significant inhibitory activity toward methicillin-resistant Staphylococcus aureus (MRSA)[1][2].

In Vitro

Neogambogic acid inhibits HCT-8, Bel-7402, BGC-823, A549, and A2780 cell proliferation, with an IC50 between 1.75 and 3 μM. Neogambogic acid induces A549 cells apoptosis arrested the cells to G0/G1 phase in vitro[1].

In Vivo

Neogambogic acid arrests A549-induced tumor growth in nude mice[1].

Molecular Weight

646.77

Formula

C₃₈H₄₆O₉

CAS No.

93772-31-7

SMILES

C/C(C(O)=O)=C/C[[email protected]@]1(OC(C)(C)[[email protected]]2([H])C3)[[email protected]@]2(OC4=C(C(O[[email protected]@](CC/C=C(C)/C)(C)C5)=C6C5O)C/C=C(C)/C)C(C(C4=C6O)=O)=C[[email protected]@]3([H])C1=O

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Neogambogic acidBacterialApoptosistummorproliferationarrestMRSAMCF-7cellsbreastcancerInhibitorinhibitorinhibit

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