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Alanine aminotransferase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldehyde Dehydrogenase (ALDH) (1) Aminotransferases (Transaminases) (3) Apoptosis (1) Bacterial (1) Biochemical Assay Reagents (3) Cholinesterase (ChE) (1) COX (1) Cytochrome P450 (2) Endogenous Metabolite (4) Environmental Pollutants (3) ERK (2) Glycosidase (1) HBV (1) IKK (1) Insecticide (3) Interleukin Related (3) Isotope-Labeled Compounds (2) JNK (1) Mitosis (1) NF-κB (3) NO Synthase (2) p38 MAPK (2) Phosphatase (2) PPAR (1) Reactive Oxygen Species (ROS) (2) Reference Standards (2) STAT (1) Thyroid Hormone Receptor (1) TNF Receptor (2) Toll-like Receptor (TLR) (1) Tyrosinase (1)
By Research Areas:	Cancer (3) Endocrinology (1) Inflammation/Immunology (5) Metabolic Disease (11) Neurological Disease (1)
Oligonucleotides:	Solvents (1)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: ASCT MARCKS Branched Chain Amino Acid Transaminase (BCAT)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-154629

Sesame Oil 2 Publications Verification	Environmental Pollutants Biochemical Assay Reagents Interleukin Related NO Synthase Aminotransferases (Transaminases) NF-κB	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Sesame Oil is a vegetable oil. Sesame Oil can be extracted from the seeds of Sesamum indicum L. Sesame Oil decreases NF-κB, aspartate aminotransferase, **alanine aminotransferase, IL-1β, IL-4 and nitric oxide**. Sesame Oil has antitumor activity against malignant melanoma. Sesame Oil has protective effects against liver damage caused by various agents such as Cisplatin (HY-17394) and Acetaminophen (HY-66005). Sesame Oil shows antinociceptive and anti-inflammatory activities .

HY-P2985

Alanine aminotransferase, Porcine heart	Endogenous Metabolite	Metabolic Disease
Alanine aminotransferase, Porcine heart is a pyridoxal enzyme that catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate .

HY-N5092

7-Methylcoumarin	Reactive Oxygen Species (ROS) Cytochrome P450	Metabolic Disease
7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. 7-Methylcoumarin is a mechanism-based inhibitor for CYP2A6. 7-Methylcoumarin significantly decreases alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl₄-induced liver damage, whilst restoring total protein (TP) and albumin (TA) levels in serum as well as preventing oxidative stress. 7-Methylcoumarin can decline mitotic activity of A. sativum promeristem .

HY-Y0284

Diethyl phthalate 2 Publications Verification	Environmental Pollutants Biochemical Assay Reagents Apoptosis Aminotransferases (Transaminases) Phosphatase	Endocrinology
Diethyl phthalate is an orally active plasticizer and detergent base. Diethyl phthalate increases the activities of ACP, ALP, SDH, and ALT in liver, muscle, or both tissues. Diethyl phthalate induces dose-dependent mortality and sluggish behavior in freshwater fish. Diethyl phthalate may induce male reproductive toxicity. Diethyl phthalate is added to plastic polymers to help maintain their flexibility .

HY-Y0496

1,4-Dichlorobenzene	Insecticide Environmental Pollutants Mitosis	Cancer
1,4-Dichlorobenzene is a non-genotoxic, orally active mitogenic/tumor-promoting carcinogen that is also widely used as a dye, resin intermediate, and deodorant, moth repellent/insecticide. 1,4-Dichlorobenzene induces liver tumors in mice and promotes the growth of spontaneous precancerous lesions, but shows no liver tumor-inducing activity in F344 rats. Exposure to 1,4-dichlorobenzene leads to elevated leukocyte counts, serum alanine aminotransferase, and blood urea nitrogen levels. Due to the hepatotoxic characteristics, 1,4-Dichlorobenzene is applicable to liver cancer-related research .

HY-W013755

Dioctyl phthalate 2 Publications Verification DNOP; Di-n-octyl phthalate; Phthalic acid dioctyl ester	Biochemical Assay Reagents Aminotransferases (Transaminases) Phosphatase Bacterial	Inflammation/Immunology
Dioctyl phthalate (DNOP) is a plasticizer. Dioctyl phthalate increases the activities of alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in the liver, as well as the levels of creatinine and urea in the kidney. Exposure to Dioctyl phthalate disrupts the homeostasis of the intestinal microbial community, increases the abundance of pathogenic bacteria, and reduces the abundance of beneficial bacteria such as Lactobacillus. Dioctyl phthalate induces significant and dose-dependent inflammatory responses in the liver, spleen and kidney of mice .

HY-P2985A

Alanine aminotransferase, Human liver	Endogenous Metabolite	Inflammation/Immunology
Alanine aminotransferase, human liver is an enzyme mainly produced in the liver. It is a pyridoxalase that catalyzes the reversible interconversion of L-alanine and 2-oxoglutamate to pyruvate and L-glutamate. Alanine aminotransferase, human liver is elevated in active anti-HMGCR myopathy. Alanine aminotransferase, human liver can be used in studies related to immune-mediated necrotizing myopathy and non-alcoholic fatty liver disease .

HY-N0854

Alisol F 1 Publications Verification	HBV ERK JNK p38 MAPK STAT NF-κB TNF Receptor Interleukin Related NO Synthase COX	Metabolic Disease Cancer
Alisol F is a protostane-type triterpenoid with anti-inflammatory and anti-hepatitis B virus activities. Alisol F inhibits LPS (HY-D1056)-induced phosphorylation of ERK, JNK, p38, STAT3 and NF-κB (p65), suppresses the production of NO, IL-6, TNF-α and IL-1β, and also downregulates the levels of iNOS and COX-2. Alisol F reduces the serum alanine aminotransferase and aspartate aminotransferase levels in mice with acute liver injury and ameliorates their liver pathological damage .

HY-113820

AZD4619	PPAR	Metabolic Disease
AZD4619 is an orally active, selective peroxisome proliferator-activated receptor α (PPARα) agonist. AZD4619 increases alanine aminotransferase 1 (ALT1) protein expression in a dose-dependent manner in human, but not in rat primary hepatocytes. AZD4619 is a lipid-lowering drug .

HY-176192

SMU-14a	Toll-like Receptor (TLR) NF-κB p38 MAPK ERK IKK TNF Receptor Interleukin Related	Inflammation/Immunology
SMU-14a is a selective Toll-like receptor 3 (TLR3) inhibitor wirh an IC₅₀ of 0.18 μM. SMU-14a reduces phosphorylation of p65, ERK, and TBK1 via NF-κB, MAPK, and IRF3 signaling pathways. SMU-14a inhibits IL-6 secretion in mouse peritoneal macrophages, downregulates TNF-α in human peripheral blood monocytes and decreases serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. SMU-14a can be used for the research of acute hepatitis .

HY-W101609

Phenylethyl isovalerate	Cholinesterase (ChE)	Others
Phenylethyl isovalerate is a synthetic flavoring substance with very low acute oral toxicity. Phenylethyl isovalerate after long-term low-dose intake increases the activity of alanine aminotransferase (ALT) and the level of sulfhydryl groups in the serum, but decreases the activity of cholinesterase (ChE) .

HY-175676

THR-β agonist 10	Thyroid Hormone Receptor	Metabolic Disease Inflammation/Immunology
THR-β agonist 10 is an orally active and selective THR-β agonist, with an EC₅₀ of 11 nM. THR-β agonist 10 significantly reduces ALT (Alanine Aminotransferase), TC (Total Cholesterol), and LDL-C (Low-Density Lipoprotein Cholesterol) levels, and improves steatosis, ballooning, inflammation and fibrosis in the metabolic dysfunction-associated steatohepatitis (MASH) mouse model. THR-β agonist 10 can be used for the study of MASH .

HY-Y0496S

1,4-Dichlorobenzene-d4	Isotope-Labeled Compounds Insecticide	Others
1,4-Dichlorobenzene-d₄ is the deuterium labeled 1,4-Dichlorobenzene. 1,4-Dichlorobenzene is a non-genotoxic, orally active mitogenic/tumor-promoting carcinogen that is also widely used as a dye, resin intermediate, and deodorant, moth repellent/insecticide. 1,4-Dichlorobenzene induces liver tumors in mice and promotes the growth of spontaneous precancerous lesions, but shows no liver tumor-inducing activity in F344 rats. 1,4-Dichlorobenzene increases the levels of white blood cell count, serum alanine aminotransferase and blood urea nitrogen in occupationally exposed populations. 1,4-Dichlorobenzene is metabolized to 2,5-dichlorophenol and excreted in urine, and this metabolite can serve as a biomarker for 1,4-Dichlorobenzene exposure. Due to its specific hepatotoxic characteristics, 1,4-Dichlorobenzene is applicable to liver cancer-related research .

HY-P2985B

Alanine aminotransferase, Human (E.coli)	Endogenous Metabolite	Metabolic Disease
Alanine aminotransferase, Human (E.coli) is a pyridoxal enzyme that catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate .

HY-P2891A

Pyruvate oxidase, Aerococcus viridans PoxB, Aerococcus viridans	Endogenous Metabolite	Others
Pyruvate oxidase, Aerococcus viridans (PoxB) is a thiamine pyrophosphate-dependent oxidase that catalyzes the oxidative decarboxylation of pyruvate to produce acetyl phosphate, carbon dioxide, and water. Pyruvate oxidase, Aerococcus viridans is an important enzyme in bacterial metabolism and can enhance ATP production. Additionally, Pyruvate oxidase, Aerococcus viridans can be used for the determination of aspartate aminotransferase and alanine aminotransferase activities .

HY-N5092R

7-Methylcoumarin (Standard)	Reference Standards Reactive Oxygen Species (ROS) Cytochrome P450	Metabolic Disease
7-Methylcoumarin (Standard) is the analytical standard of 7-Methylcoumarin. This product is intended for research and analytical applications. 7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. 7-Methylcoumarin is a mechanism-based inhibitor for CYP2A6. 7-Methylcoumarin significantly decreases alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl₄-induced liver damage, whilst restoring total protein (TP) and albumin (TA) levels in serum as well as preventing oxidative stress. 7-Methylcoumarin can decline mitotic activity of A. sativum promeristem .

HY-109089S

Epeleuton-d5 15(S)-HEPE-d₅ ethyl ester; 15(S)-Hydoxy EPA-d₅ ethyl ester; 15(S)-Hydoxy eicosapetaeoic acid-d₅ ethyl ester	Isotope-Labeled Compounds	Others
Epeleuton-d₅ (15(S)-HEPE-d₅ ethyl ester) is deuterium labeled Epeleuton. Epeleuton is a second-generation synthetic N-3 fatty acid derivative with activity in patients with non-alcoholic fatty liver disease, although it did not reach the primary endpoints of alanine aminotransferase and liver stiffness, but it can significantly reduce triglycerides, glycated hemoglobin, plasma glucose and inflammatory markers .

HY-Y0496R

1,4-Dichlorobenzene (Standard)	Reference Standards Insecticide	Others
1,4-Dichlorobenzene (Standard) is the analytical standard of 1,4-Dichlorobenzene. This product is intended for research and analytical applications. 1,4-Dichlorobenzene is a non-genotoxic, orally active mitogenic/tumor-promoting carcinogen that is also widely used as a dye, resin intermediate, and deodorant, moth repellent/insecticide. 1,4-Dichlorobenzene induces liver tumors in mice and promotes the growth of spontaneous precancerous lesions, but shows no liver tumor-inducing activity in F344 rats. 1,4-Dichlorobenzene increases the levels of white blood cell count, serum alanine aminotransferase and blood urea nitrogen in occupationally exposed populations. 1,4-Dichlorobenzene is metabolized to 2,5-dichlorophenol and excreted in urine, and this metabolite can serve as a biomarker for 1,4-Dichlorobenzene exposure. Due to its specific hepatotoxic characteristics, 1,4-Dichlorobenzene is applicable to liver cancer-related research .

HY-N17495

Luteolin 7-O-(6-O-malonyl-β-D-glucoside)	Others	Metabolic Disease
Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is an orally active flavonoid free radical scavenger. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) scavenges free radicals, inhibits the activity elevation of aspartate aminotransferase and alanine aminotransferase in mouse plasma, as well as the elevation of liver lipid hydroperoxide content. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is applicable for liver injury research .

HY-N15464

Antihepatotoxic agent-1	Aldehyde Dehydrogenase (ALDH)	Metabolic Disease
Antihepatotoxic agent-1 is a cerebroside present in Lycium chinense Fruits with antihepatotoxic activity. Antihepatotoxic agent-1 exerts a protective effect by blocking the release of **alanine aminotransferase and sorbitol dehydrogenase** from primary cultured rat hepatocytes intoxicated with carbon tetrachloride. Antihepatotoxic agent-1 can be used in studies related to liver injury .

HY-N19646

[8]-Dehydrogingerdione	Glycosidase Tyrosinase	Metabolic Disease
[8]-Dehydrogingerdione is a Hydroxyphenylalkanone. [8]-Dehydrogingerdione can be isolated from the seeds of Aframomum melegueta and the rhizomes of Curcuma xanthorrhia. [8]-Dehydrogingerdione acts as an inhibitor of α-glucosidase and Tyrosinase, with an IC₅₀ value of 19.5 μM against α-glucosidase and an approximate IC₅₀ value of 100 μM against tyrosinase. [8]-Dehydrogingerdione can be used in diabetes-related research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N5092

7-Methylcoumarin	Microorganisms Coumarins Metabolic Disease Phenylpropanoids Disease Research Fields Source Classification	Reactive Oxygen Species (ROS) Cytochrome P450
7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. 7-Methylcoumarin is a mechanism-based inhibitor for CYP2A6. 7-Methylcoumarin significantly decreases alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl₄-induced liver damage, whilst restoring total protein (TP) and albumin (TA) levels in serum as well as preventing oxidative stress. 7-Methylcoumarin can decline mitotic activity of A. sativum promeristem .

HY-N0854

Alisol F 1 Publications Verification	Infection Triterpenes Structural Classification Classification of Application Fields Terpenoids Alisma orinentale (Samuel.) Juz. Alismataceae Plants Disease Research Fields Source Classification	HBV ERK JNK p38 MAPK STAT NF-κB TNF Receptor Interleukin Related NO Synthase COX
Alisol F is a protostane-type triterpenoid with anti-inflammatory and anti-hepatitis B virus activities. Alisol F inhibits LPS (HY-D1056)-induced phosphorylation of ERK, JNK, p38, STAT3 and NF-κB (p65), suppresses the production of NO, IL-6, TNF-α and IL-1β, and also downregulates the levels of iNOS and COX-2. Alisol F reduces the serum alanine aminotransferase and aspartate aminotransferase levels in mice with acute liver injury and ameliorates their liver pathological damage .

HY-W101609

Phenylethyl isovalerate	Michelia × alba DC. Structural Classification Natural Products Magnoliaceae Plants Source Classification	Cholinesterase (ChE)
Phenylethyl isovalerate is a synthetic flavoring substance with very low acute oral toxicity. Phenylethyl isovalerate after long-term low-dose intake increases the activity of alanine aminotransferase (ALT) and the level of sulfhydryl groups in the serum, but decreases the activity of cholinesterase (ChE) .

HY-N5092R

7-Methylcoumarin (Standard)	Microorganisms Coumarins Phenylpropanoids Source Classification	Reference Standards Reactive Oxygen Species (ROS) Cytochrome P450
7-Methylcoumarin (Standard) is the analytical standard of 7-Methylcoumarin. This product is intended for research and analytical applications. 7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. 7-Methylcoumarin is a mechanism-based inhibitor for CYP2A6. 7-Methylcoumarin significantly decreases alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl₄-induced liver damage, whilst restoring total protein (TP) and albumin (TA) levels in serum as well as preventing oxidative stress. 7-Methylcoumarin can decline mitotic activity of A. sativum promeristem .

HY-N17495

Luteolin 7-O-(6-O-malonyl-β-D-glucoside)	Structural Classification Flavonoids Dendranthema morifolium (Ramat.) Tzvel. Plants Compositae Other Flavonoids Source Classification	Others
Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is an orally active flavonoid free radical scavenger. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) scavenges free radicals, inhibits the activity elevation of aspartate aminotransferase and alanine aminotransferase in mouse plasma, as well as the elevation of liver lipid hydroperoxide content. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is applicable for liver injury research .

HY-N15464

Antihepatotoxic agent-1	Structural Classification Solanaceae Plants Lycium chinense Miller Saccharides Monosaccharides Source Classification	Aldehyde Dehydrogenase (ALDH)
Antihepatotoxic agent-1 is a cerebroside present in Lycium chinense Fruits with antihepatotoxic activity. Antihepatotoxic agent-1 exerts a protective effect by blocking the release of **alanine aminotransferase and sorbitol dehydrogenase** from primary cultured rat hepatocytes intoxicated with carbon tetrachloride. Antihepatotoxic agent-1 can be used in studies related to liver injury .

HY-N19646

[8]-Dehydrogingerdione	Zingiber officinale Roscoe Structural Classification Monophenols Polygalaceae Phenols Plants Polygala tenuifolia Willd. Source Classification Zingiberaceae	Glycosidase Tyrosinase
[8]-Dehydrogingerdione is a Hydroxyphenylalkanone. [8]-Dehydrogingerdione can be isolated from the seeds of Aframomum melegueta and the rhizomes of Curcuma xanthorrhia. [8]-Dehydrogingerdione acts as an inhibitor of α-glucosidase and Tyrosinase, with an IC₅₀ value of 19.5 μM against α-glucosidase and an approximate IC₅₀ value of 100 μM against tyrosinase. [8]-Dehydrogingerdione can be used in diabetes-related research .

Species:	Human (1) Rat (2)
Tag:	His (3)
Source:	Sf9 insect cells (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P702494

	GPT Protein, Human (His) AAT1; Alanine aminotransferase 1; Alanine aminotransferase; ALAT1_HUMAN; ALT1; Glutamate pyruvate transaminase 1; Glutamic Alanine transaminase 1; Glutamic pyruvate transaminase (Alanine aminotransferase); Glutamic pyruvic transaminase 1; Glutamic--Alanine transaminase 1; Glutamic--pyruvic transaminase 1; GPT 1; gpt; GPT1	Human	E. coli
	The GPT1 protein is a key player that catalyzes the reversible cleavage of L-arginine succinate, which is critical in the urea cycle, aids in hepatic nitrogen detoxification and promotes de novo L-arginine synthesis. GPT1 regulates intracellular and extracellular L-arginine pools, which are critical for nitrogen homeostasis. GPT Protein, Human (His) is the recombinant human-derived GPT1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P75158

	GPT Protein, Rat (sf9, His) Alanine aminotransferase 1; ALT1; GPT 1; Aat1	Rat	Sf9 insect cells
	GPT proteins play a key role in cellular nitrogen metabolism by catalyzing the reversible ammonia interaction between alanine and 2-oxoglutarate to produce pyruvate and glutamate products. This enzyme activity is an integral part of the dynamic balance of amino acid metabolism and contributes to the interconversion of key metabolites. GPT Protein, Rat (sf9, His) is the recombinant rat-derived GPT protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75797

	GPT2 Protein, Rat (sf9, His) Alanine aminotransferase 2; ALT2; GPT 2; AAT2	Rat	Sf9 insect cells
	GPT2 protein is predicted by L-alanine:2-oxoglutarate aminotransferase activity and is involved in insulin response, gluconeogenesis, and testosterone response. It is located in the extracellular space and mitochondria, is a biomarker for type 2 diabetes, and is orthologous to human GPT2. GPT2 Protein, Rat (sf9, His) is the recombinant rat-derived GPT2 protein, expressed by Sf9 insect cells , with C-His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-Y0496S

1,4-Dichlorobenzene-d4
1,4-Dichlorobenzene-d₄ is the deuterium labeled 1,4-Dichlorobenzene. 1,4-Dichlorobenzene is a non-genotoxic, orally active mitogenic/tumor-promoting carcinogen that is also widely used as a dye, resin intermediate, and deodorant, moth repellent/insecticide. 1,4-Dichlorobenzene induces liver tumors in mice and promotes the growth of spontaneous precancerous lesions, but shows no liver tumor-inducing activity in F344 rats. 1,4-Dichlorobenzene increases the levels of white blood cell count, serum alanine aminotransferase and blood urea nitrogen in occupationally exposed populations. 1,4-Dichlorobenzene is metabolized to 2,5-dichlorophenol and excreted in urine, and this metabolite can serve as a biomarker for 1,4-Dichlorobenzene exposure. Due to its specific hepatotoxic characteristics, 1,4-Dichlorobenzene is applicable to liver cancer-related research .

1,4-Dichlorobenzene-d4

1,4-Dichlorobenzene-d₄ is the deuterium labeled 1,4-Dichlorobenzene. 1,4-Dichlorobenzene is a non-genotoxic, orally active mitogenic/tumor-promoting carcinogen that is also widely used as a dye, resin intermediate, and deodorant, moth repellent/insecticide. 1,4-Dichlorobenzene induces liver tumors in mice and promotes the growth of spontaneous precancerous lesions, but shows no liver tumor-inducing activity in F344 rats. 1,4-Dichlorobenzene increases the levels of white blood cell count, serum alanine aminotransferase and blood urea nitrogen in occupationally exposed populations. 1,4-Dichlorobenzene is metabolized to 2,5-dichlorophenol and excreted in urine, and this metabolite can serve as a biomarker for 1,4-Dichlorobenzene exposure. Due to its specific hepatotoxic characteristics, 1,4-Dichlorobenzene is applicable to liver cancer-related research .

HY-109089S

Epeleuton-d5
Epeleuton-d₅ (15(S)-HEPE-d₅ ethyl ester) is deuterium labeled Epeleuton. Epeleuton is a second-generation synthetic N-3 fatty acid derivative with activity in patients with non-alcoholic fatty liver disease, although it did not reach the primary endpoints of alanine aminotransferase and liver stiffness, but it can significantly reduce triglycerides, glycated hemoglobin, plasma glucose and inflammatory markers .

Epeleuton-d5

Epeleuton-d₅ (15(S)-HEPE-d₅ ethyl ester) is deuterium labeled Epeleuton. Epeleuton is a second-generation synthetic N-3 fatty acid derivative with activity in patients with non-alcoholic fatty liver disease, although it did not reach the primary endpoints of alanine aminotransferase and liver stiffness, but it can significantly reduce triglycerides, glycated hemoglobin, plasma glucose and inflammatory markers .

Cat. No.	Product Name		Classification

HY-154629

Sesame Oil 2 Publications Verification		Solvents
Sesame Oil is a vegetable oil. Sesame Oil can be extracted from the seeds of Sesamum indicum L. Sesame Oil decreases NF-κB, aspartate aminotransferase, **alanine aminotransferase, IL-1β, IL-4 and nitric oxide**. Sesame Oil has antitumor activity against malignant melanoma. Sesame Oil has protective effects against liver damage caused by various agents such as Cisplatin (HY-17394) and Acetaminophen (HY-66005). Sesame Oil shows antinociceptive and anti-inflammatory activities .

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