2. Metabolic Enzyme/Protease
  3. Glycosidase Tyrosinase
  4. [8]-Dehydrogingerdione

[8]-Dehydrogingerdione is a Hydroxyphenylalkanone. [8]-Dehydrogingerdione can be isolated from the seeds of Aframomum melegueta and the rhizomes of Curcuma xanthorrhia. [8]-Dehydrogingerdione acts as an inhibitor of α-glucosidase and Tyrosinase, with an IC50 value of 19.5 μM against α-glucosidase and an approximate IC50 value of 100 μM against tyrosinase. [8]-Dehydrogingerdione can be used in diabetes-related research.

For research use only. We do not sell to patients.

[8]-Dehydrogingerdione

[8]-Dehydrogingerdione Chemical Structure

CAS No. : 77334-08-8

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[8]-Dehydrogingerdione Related Antibodies

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Description

[8]-Dehydrogingerdione is a Hydroxyphenylalkanone. [8]-Dehydrogingerdione can be isolated from the seeds of Aframomum melegueta and the rhizomes of Curcuma xanthorrhia. [8]-Dehydrogingerdione acts as an inhibitor of α-glucosidase and Tyrosinase, with an IC50 value of 19.5 μM against α-glucosidase and an approximate IC50 value of 100 μM against tyrosinase. [8]-Dehydrogingerdione can be used in diabetes-related research[1][2].

IC50 & Target[1]

α‑glucosidase

19.5 μM (IC50)

Tyrosinase

100 μM (IC50)

In Vitro

[8]-Dehydrogingerdione (1.0-100 μM; 30 min) moderately inhibits mushroom tyrosinase, with an IC50 value of approximately 100 μM[1].
[8]-Dehydrogingerdione (1-100 μM; 30 min) potently inhibits α-glucosidase from Saccharomyces cerevisiae, with an IC50 value of 19.5 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

[8]-Dehydrogingerdione Related Antibodies
Molecular Weight

318.41

Formula

C19H26O4
CAS No.
SMILES

CCCCCCCC(CC(/C=C/C1=CC(OC)=C(C=C1)O)=O)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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[8]-Dehydrogingerdione Related Classifications

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Help & FAQs
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[8]-Dehydrogingerdione77334-08-8GlycosidaseTyrosinaseSprague Dawley rat hepatocytestyrosinaseSaccharomyces cerevisiaediabetesthiobarbituric acid reactive substancesalanine aminotransferaseα-glucosidasemushroom tyrosinaserat hepatocytesglutathioneInhibitorinhibitorinhibit

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