77334-08-8
![[8]-Dehydrogingerdione Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-n19646.gif "[8]-Dehydrogingerdione Chemical Structure")
77334-08-8
Chemical Structure
[8]-Dehydrogingerdione
- CAS No.: 77334-08-8
- Formula:C19H26O4
- Molecular Weight:318.41
InChIKey: QOJHXMDTWFYFRL-PKNBQFBNSA-N
SMILES: CCCCCCCC(CC(/C=C/C1=CC(OC)=C(C=C1)O)=O)=O
Biological Activity: [8]-Dehydrogingerdione is a Hydroxyphenylalkanone. [8]-Dehydrogingerdione can be isolated from the seeds of Aframomum melegueta and the rhizomes of Curcuma xanthorrhia. [8]-Dehydrogingerdione acts as an inhibitor of α-glucosidase and Tyrosinase, with an IC50 value of 19.5 μM against α-glucosidase and an approximate IC50 value of 100 μM against tyrosinase. [8]-Dehydrogingerdione can be used in diabetes-related research[1][2].
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[8]-Dehydrogingerdione | -Dehydrogingerdione is a Hydroxyphenylalkanone. -Dehydrogingerdione can be isolated from the seeds of Aframomum melegueta and the rhizomes of Curcuma xanthorrhia. -Dehydrogingerdione acts as an inhibitor of α-glucosidase and Tyrosinase, with an IC50 value of 19.5 μM against α-glucosidase and an approximate IC50 value of 100 μM against tyrosinase. -Dehydrogingerdione can be used in diabetes-related research. | |||||||||||||||||||||
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References
- [1]. Nguyen HX, et al. Two new gingerol derivatives from the rhizome of Curcuma xanthorrhiza D.Dietr. Nat Prod Res. 2025 Sep 21:1-11. [Content Brief]
- [2]. El-Halawany AM, et al. Protective effect of Aframomum melegueta phenolics against CCl₄-induced rat hepatocytes damage; role of apoptosis and pro-inflammatory cytokines inhibition. Sci Rep. 2014;4:5880. Published 2014 Jul 30. [Content Brief]
