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  3. Plants Flavonoids
  4. Compositae Other Flavonoids
  5. Dendranthema morifolium (Ramat.) Tzvel.
  6. Luteolin 7-O-(6-O-malonyl-β-D-glucoside)

Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is an orally active flavonoid free radical scavenger. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) scavenges free radicals, inhibits the activity elevation of aspartate aminotransferase and alanine aminotransferase in mouse plasma, as well as the elevation of liver lipid hydroperoxide content. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is applicable for liver injury research.

For research use only. We do not sell to patients.

Luteolin 7-O-(6-O-malonyl-β-D-glucoside)

Luteolin 7-O-(6-O-malonyl-β-D-glucoside) Chemical Structure

CAS No. : 98767-38-5

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Luteolin 7-O-(6-O-malonyl-β-D-glucoside) Related Antibodies

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Description

Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is an orally active flavonoid free radical scavenger. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) scavenges free radicals, inhibits the activity elevation of aspartate aminotransferase and alanine aminotransferase in mouse plasma, as well as the elevation of liver lipid hydroperoxide content. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is applicable for liver injury research[1].

In Vivo

Luteolin 7-O-(6-O-malonyl-β-D-glucoside) (Compound 3) (22 mg/mouse; p.o.; single administration) significantly inhibits the Carbon Tetrachloride (CCl4) (HY-Y0298)-induced increases in plasma AST and ALT activities as well as hepatic lipid hydroperoxide content in mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: ddY (male, 8-week-old, ~38 g, liver injury model via CCl4 injection)[1]
Dosage: 22 mg
Administration: p.o.; single dose
Result: Significantly suppressed CCl4-induced increases in plasma aspartate aminotransferase (AST) activity.
Significantly suppressed CCl4-induced increases in plasma alanine aminotransferase (ALT) activity.
Significantly suppressed CCl4-induced increases in liver lipid hydroperoxide content.
Molecular Weight

534.42

Formula

C24H22O14
CAS No.
SMILES

O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)COC(CC(O)=O)=O)C=C2OC(C4=CC(O)=C(C=C4)O)=C1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Luteolin 7-O-(6-O-malonyl-β-D-glucoside) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Luteolin 7-O-(6-O-malonyl-β-D-glucoside)98767-38-5Otherscarbon tetrachloride-induced liver injuryhepatocyte microsomesliver lipid hydroperoxidealanine aminotransferasetrichloromethyl radicaledible chrysanthemumfree radicalsChrysanthemum×morifolium Ramat. forma esculentum Makinoc.v Kotobukimale ddY miceaspartate aminotransferaseInhibitorinhibitorinhibit

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