Luteolin 7-O-(6-O-malonyl-β-D-glucoside)
Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is an orally active flavonoid free radical scavenger. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) scavenges free radicals, inhibits the activity elevation of aspartate aminotransferase and alanine aminotransferase in mouse plasma, as well as the elevation of liver lipid hydroperoxide content. Luteolin 7-O-(6-O-malonyl-β-D-glucoside) is applicable for liver injury research.
For research use only. We do not sell to patients.
- CAS No.: 98767-38-5
- Formula: C24H22O14
- Molecular Weight:534.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:ddY (male, 8-week-old, ~38 g, liver injury model via CCl4 injection)[1]
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Dosage:22 mg
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Administration:p.o.; single dose
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Result:Significantly suppressed CCl4-induced increases in plasma aspartate aminotransferase (AST) activity.
Significantly suppressed CCl4-induced increases in plasma alanine aminotransferase (ALT) activity.
Significantly suppressed CCl4-induced increases in liver lipid hydroperoxide content.
Chemical Information
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CAS No. 98767-38-5
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Molecular Weight 534.42
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Formula C24H22O14
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SMILES
O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)COC(CC(O)=O)=O)C=C2OC(C4=CC(O)=C(C=C4)O)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Luteolin 7-O-(6-O-malonyl-β-D-glucoside) Related Classifications
HY-N17495 Related Classifications
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Keywords
- Luteolin 7-O-(6-O-malonyl-β-D-glucoside)
- 98767-38-5
- Free Radical Scavengers
- Others
- carbon tetrachloride-induced liver injury
- hepatocyte microsomes
- liver lipid hydroperoxide
- alanine aminotransferase
- trichloromethyl radical
- edible chrysanthemum
- free radicals
- Chrysanthemum×morifolium Ramat. forma esculentum Makino
- c.v Kotobuki
- male ddY mice
- aspartate aminotransferase
- Inhibitor
- inhibitor
- inhibit