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Pathways Recommended:	Vitamin D Related/Nuclear Receptor PI3K/Akt/mTOR

Results for "

Vitamin K

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Bacterial (2) Dihydroorotate Dehydrogenase (1) DNA/RNA Synthesis (1) Drug Metabolite (1) Endogenous Metabolite (18) Fungal (1) Isotope-Labeled Compounds (9) NF-κB (1) NO Synthase (1) Parasite (2) Pyruvate Kinase (1) Reactive Oxygen Species (1) SARS-CoV (1)
By Research Areas:	Cancer (11) Cardiovascular Disease (23) Infection (6) Inflammation/Immunology (4) Metabolic Disease (5)

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: VD/VDR

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B2172

Vitamin K	Endogenous Metabolite	Cardiovascular Disease
Vitamin K, the blood-clotting vitamin, is important for the function of numerous proteins within the body, such as the coagulation factors, osteocalcin and matrix-Gla protein.

HY-B1508

Vitamin K4 Acetomenaphthone	Endogenous Metabolite Apoptosis	Cardiovascular Disease Cancer
Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. Vitamin K4 arrests the cells in S phase and induces apoptosis. Vitamin K4 can be used for the research of cancer, such as prostate cancer and osteosarcoma .

HY-N2552

Vitamin K5 hydrochloride	Others	Infection
Vitamin K5 (hydrochloride) is a naphthoquinones compound, shows trichomonacidal activity in vitro. Vitamin K5(hydrochloride) can be used for the research of anti-infection .

HY-N0684S

Vitamin K1-d7	Endogenous Metabolite	Cardiovascular Disease
Vitamin K1-d₇ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1][2].

HY-B1508R

Vitamin K4 (Standard)	Endogenous Metabolite Apoptosis	Cardiovascular Disease Cancer
Vitamin K4 (Standard) is the analytical standard of Vitamin K4. This product is intended for research and analytical applications. Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. Vitamin K4 arrests the cells in S phase and induces apoptosis. Vitamin K4 can be used for the research of cancer, such as prostate cancer and osteosarcoma .

HY-132389S

Vitamin K3-d8

Isotope-Labeled Compounds Others

Vitamin K3-d₈ is the deuterium labeled Vitamin K3[1].
HY-109569

Vitamin K2

Endogenous Metabolite Metabolic Disease

Vitamin K2 is an endogenous metabolite.

Vitamin K3-d8	Isotope-Labeled Compounds	Others
Vitamin K3-d₈ is the deuterium labeled Vitamin K3[1].

Vitamin K2	Endogenous Metabolite	Metabolic Disease
Vitamin K2 is an endogenous metabolite.

HY-113164

Vitamin K1 2,3-epoxide	Endogenous Metabolite	Others
Vitamin K1 2,3-epoxide is an inactive metabolite form of Vitamin K1 (HY-N0684), which is reduced to active vitamin by microsomal epoxide reductase in the vitamin K epoxide cycle. Vitamin K1 2,3-epoxide is involved in blood clotting .

HY-N0684

Vitamin K1 2 Publications Verification Phylloquinone; Phytomenadione	Endogenous Metabolite	Cardiovascular Disease
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-112499

Menaquinone-7 1 Publications Verification Vitamin K2-7; Vitamin K2(35); Vitamin MK-7	Others	Cardiovascular Disease
Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs (orally active), is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. Menaquinone-7 has a well-researched potential in the prevention of aging-induced bone degeneration. Menaquinone-7 is also a pharmacological option for activating Gla matrix protein and intervening in the progression of calcific aortic stenosis (CAVS) .

HY-B1814

Vitamin K5 Synkamin; Synkamin base	Pyruvate Kinase Bacterial Fungal	Infection Cancer
Vitamin K5 (Synkamin) is a photosensitizer and a antimicrobial agent. Vitamin K5 is a specific PKM2 inhibitor with IC₅₀ values of 28, 191 and 120 μM for PKM2, PKM1 and PKL. Vitamin K5 induces apoptosis of colon 26 cells. Vitamin K5 can be used for the research of infection and cancer, and it also can be used as a preservative for pharmaceuticals, foods, and beverages .

HY-112499S

Menaquinone-7-d7 Vitamin K2-7-d₇; Vitamin K2(35)-d₇; Vitamin MK-7-d₇	Isotope-Labeled Compounds	Cardiovascular Disease
Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-B0332

Menadione Maximum Cited Publications 14 Publications Verification Vitamin K3	Endogenous Metabolite	Others
Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer .

HY-113164S

Vitamin K1 2,3-epoxide-d7

Isotope-Labeled Compounds Others

Vitamin K1 2,3-epoxide-d₇ is the deuterium labeled Vitamin K1 2,3-epoxide[1].

Vitamin K1 2,3-epoxide-d7	Isotope-Labeled Compounds	Others
Vitamin K1 2,3-epoxide-d₇ is the deuterium labeled Vitamin K1 2,3-epoxide[1].

HY-112499R

Menaquinone-7 (Standard) Vitamin K2-7(Standard); Vitamin K2(35)(Standard); Vitamin MK-7 (Standard)	Others	Cardiovascular Disease
Menaquinone-7 (Standard) is the analytical standard of Menaquinone-7. This product is intended for research and analytical applications. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs (orally active), is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. Menaquinone-7 has a well-researched potential in the prevention of aging-induced bone degeneration. Menaquinone-7 is also a pharmacological option for activating Gla matrix protein and intervening in the progression of calcific aortic stenosis (CAVS) .

HY-N0684S1

Vitamin K1-d4 Phylloquinone-d₄; Phytomenadione-d₄	Endogenous Metabolite	Cardiovascular Disease
Vitamin K1-d₄ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1].

HY-B2156

Menaquinone-4 1 Publications Verification Vitamin K2(MK-4); Menaquinone K4	Endogenous Metabolite	Cancer
Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-112499S1

Menaquinone-7-13C6 Vitamin K2-7-¹³C₆; Vitamin K2(35)-¹³C₆; Vitamin MK-7-¹³C₆	Isotope-Labeled Compounds	Cardiovascular Disease
Menaquinone-7- ¹³C₆ is the ¹³C-labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-N0684S4

Vitamin K1-d3 Phylloquinone-d₃; Phytomenadione-d₃	Endogenous Metabolite Isotope-Labeled Compounds	Cardiovascular Disease
Vitamin K1-d₃ (Phylloquinone-d₃; Phytomenadione-d₃) is deuterium-labeled Vitamin K1 (HY-N0684) .

HY-N0684S3

Vitamin K1-13C6 Phylloquinone-¹³C₆; Phytomenadione-¹³C₆	Endogenous Metabolite	Cardiovascular Disease
Vitamin K1- ¹³C₆ is the ¹³C-labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-B2156S

Menaquinone-4-d7 Vitamin K2(MK-4)-d₇; Menaquinone K4-d₇	Endogenous Metabolite	Cancer
Menaquinone-4-d₇ (Vitamin K2(MK-4)-d7) is the deuterium labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-B0332S

Menadione-d3 Vitamin K3-d₃	Endogenous Metabolite	Others
Menadione-d₃ is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.

HY-B2156S1

Menaquinone-4-13C6 Vitamin K2(MK-4)-¹³C₆; Menaquinone K4-¹³C₆	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Menaquinone-4- ¹³C₆ is the ¹³C-labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-B1897A

Menadione bisulfite sodium Menadione sodium bisulfite; Vitamin K3 sodium bisulfite	Others	Others
Menadione bisulfite (sodium) is used as an agent to induce acute oxidative stress, and to function as a plant-defense activator against several pathogens.

HY-N0684AS

cis-Vitamin K1-d7

Endogenous Metabolite Isotope-Labeled Compounds Others

cis-Vitamin K1-d₇ is the deuterium labeled cis-Vitamin K1, is an endogenous metabolite of Vitamin K .
HY-N0684A

cis-Vitamin K1

cis-Phylloquinone; cis-Phytomenadione
Endogenous Metabolite Cardiovascular Disease

Cis-Vitamin K1 is an endogenous metabolite of Vitamin K .
HY-106561

Tioclomarol

Others Cardiovascular Disease

Tioclomarol, a coumarin anticoagulant, is a vitamin K antagonist .

*cis-Vitamin* K1-d7**	Endogenous Metabolite Isotope-Labeled Compounds	Others
cis-Vitamin K1-d₇ is the deuterium labeled cis-Vitamin K1, is an endogenous metabolite of Vitamin K .

*cis-Vitamin* K1** cis-Phylloquinone; cis-Phytomenadione	Endogenous Metabolite	Cardiovascular Disease
Cis-Vitamin K1 is an endogenous metabolite of Vitamin K .

Tioclomarol	Others	Cardiovascular Disease
Tioclomarol, a coumarin anticoagulant, is a vitamin K antagonist .

HY-121556

Rufigallol	Reactive Oxygen Species Parasite	Infection
Rufigallol is one of the earliest systems reported to form columnar mesophases. Rufigallol is also an oxidant agent. Rufigallol acts in a pro-oxidant fashion to produce oxygen radicals inside parasitized erythrocytes. Rufigallol has vitamin K activity and antimalarial activity .

HY-111186

Flocoumafen WL 108366	Others	Others
Flocoumafen (WL 108366) is a family of orally active vitamin K antagonist (VKA) molecules. Flocoumafen is a second generation anticoagulant rodenticide (ARs) .

HY-116601

6-Hydroxywarfarin	Others	Others
6-Hydroxywarfarin is a metabolite of (+) -warfarin. 6-Hydroxywarfarin is a weaker vitamin K antagonist. 6-Hydroxywarfarin is metabolized by the cytochrome P450 isomer 2C9 (CYP2C9) .

HY-W017464

NAPQI	Drug Metabolite Endogenous Metabolite	Metabolic Disease
NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver .

HY-N6961

Lapachol 1 Publications Verification	Dihydroorotate Dehydrogenase DNA/RNA Synthesis Parasite	Infection Inflammation/Immunology Cancer
Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity .

HY-U00017

Coumetarol

Dicumoxane; Ph 137
Others Metabolic Disease

Coumetarol (Dicumoxane) is a vitamin K antagonist.
HY-16516

Vitamin CK3

Others Cancer

Vitamin CK3 is the combination of Vitamin C and vitamin K3 (100:1 ratio) and has been shown to inhibit tumor growth and lung metastasis.
HY-B1014

Acenocoumarol

Others Cardiovascular Disease

Acenocoumarol is an anticoagulant that functions as a Vitamin K antagonist.
HY-B0325

Phenindione

Rectadione
Others Cardiovascular Disease

Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

Coumetarol Dicumoxane; Ph 137	Others	Metabolic Disease
Coumetarol (Dicumoxane) is a vitamin K antagonist.

Vitamin CK3	Others	Cancer
Vitamin CK3 is the combination of Vitamin C and vitamin K3 (100:1 ratio) and has been shown to inhibit tumor growth and lung metastasis.

Acenocoumarol	Others	Cardiovascular Disease
Acenocoumarol is an anticoagulant that functions as a Vitamin K antagonist.

Phenindione Rectadione	Others	Cardiovascular Disease
Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

HY-14854

Tecarfarin ATI-5923	Others	Cardiovascular Disease
Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X . Tecarfarin has the antithrombotic activity .

HY-N2853

D-α-Tocopherylquinone α-Tocopherylquinone	Others	Cancer
D-α-Tocopherylquinone (α-Tocopherylquinone) is a quinone, can be isolated from Phaeodactylum tricornutum. D-α-Tocopherylquinone is a oxidation product of α-Tocopherol (vitamin E). D-α-Tocopherylquinone can act as an anticoagulant and as an antioxidant .

HY-14854A

Tecarfarin sodium ATI-5923 sodium	Others	Metabolic Disease
Tecarfarin sodium (ATI-5923 sodium) is a novel orally active non-competitive vitamin K epoxide reductase (VKOR) antagonist, impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X . Tecarfarin sodium has the antithrombotic activity .

HY-B0918

Chlorindione

Chlophenadione; Indaliton; G-25766
Others Cardiovascular Disease

Chlorindione (Chlophenadione) is a potent anticoagulant. Chlorindione also is a vitamin K1 antagonist .
HY-A0145

Phenprocoumon

Others Others

Phenprocoumon is a coumarin derivative that acts as a long acting oral anticoagulant and an antagonist of vitamin K.

Chlorindione Chlophenadione; Indaliton; G-25766	Others	Cardiovascular Disease
Chlorindione (Chlophenadione) is a potent anticoagulant. Chlorindione also is a vitamin K1 antagonist .

Phenprocoumon	Others	Others
Phenprocoumon is a coumarin derivative that acts as a long acting oral anticoagulant and an antagonist of vitamin K.

HY-B0325S

Phenindione-d5 Rectadione d₅	Isotope-Labeled Compounds	Cardiovascular Disease
Phenindione-d₅ is deuterium labeled Phenindione, which is an anticoagulant which functions as a Vitamin K antagonist.

HY-B1014S

Acenocoumarol-d5	Isotope-Labeled Compounds	Cardiovascular Disease
Acenocoumarol-d₅ is the deuterium labeled Acenocoumarol. Acenocoumarol is an anticoagulant that functions as a Vitamin K antagonist[1][2].

HY-131501

Menaquinone 9	Others	Metabolic Disease
Menaquinone 9 is a vitamin K2 (HY-109569) analog. Menaquinone 9 acts as a prothrombogenic agent and functional electron transfer component in nitrate reductase .

HY-138137

Menaquinone 6	Bacterial	Infection
Menaquinone 6 is a active product found in Wolinella succinogenes. Menaquinone 6 is a form of vitamin K2 (HY-109569) that has antimicrobial activity .

HY-B0918R

Chlorindione (Standard)	Others	Cardiovascular Disease
Chlorindione (Standard) is the analytical standard of Chlorindione. This product is intended for research and analytical applications. Chlorindione (Chlophenadione) is a potent anticoagulant. Chlorindione also is a vitamin K1 antagonist .

HY-W011474

Geranylgeraniol	NF-κB	Inflammation/Immunology
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-118160

PPM-18 NSC 73233	NO Synthase	Inflammation/Immunology Cancer
PPM-18 (NSC 73233), a potent anti-inflammatory agent, inhibits nitric oxide synthase expression. PPM-18 is a potent inhibitor of iNOS expression by blocking the binding of NF-κB to promoter . PPM-18, an analog of Vitamin K, induces autophagy and apoptosis in bladder cancer cells through ROS and AMPK signaling pathways .

HY-157022

SARS-CoV-2-IN-67	SARS-CoV	Infection
SARS-CoV-2-IN-67 (Compound 16), a vitamin K derivatives, has anti-SARS-CoV-2 activity (EC₅₀: 64.8 μM in VeroE6/TMPRSS2 cells). SARS-CoV-2-IN-67 inhibits SARS-CoV-2 RdRp activity .

HY-121814A

(R)-Acenocoumarol (R)-Acenocoumarin; (R)-Nicoumalone	Others	Others
(R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) is a short-acting oral anticoagulant that, like warfarin, works by inhibiting vitamin K epoxide reductase. In vitro evaluations have shown that (R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) has a higher intrinsic anticoagulant potency than warfarin and phenprocoumon. (R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) has a single chiral center that produces two different enantiomeric forms. (R)-(R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) has a longer plasma elimination half-life (6.6 hours) and a slower plasma clearance rate (1.9 L/hour) compared to the (S)-enantiomer (1.8 hours, 28.5 L/hour). (R)-(R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) is a more potent anticoagulant in vivo than the (S)-enantiomer.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B2172

Vitamin K	Cardiovascular Disease Natural Products other families Microorganisms Classification of Application Fields Animals Source classification Plants Disease Research Fields	Endogenous Metabolite
Vitamin K, the blood-clotting vitamin, is important for the function of numerous proteins within the body, such as the coagulation factors, osteocalcin and matrix-Gla protein.

HY-B1508

Vitamin K4 Acetomenaphthone	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Apoptosis
Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. Vitamin K4 arrests the cells in S phase and induces apoptosis. Vitamin K4 can be used for the research of cancer, such as prostate cancer and osteosarcoma .

HY-N0684

Vitamin K1 2 Publications Verification Phylloquinone; Phytomenadione	Cardiovascular Disease Quinones Human Gut Microbiota Metabolites other families Microorganisms Classification of Application Fields Source classification Plants Endogenous metabolite Naphthalene Quinones Disease Research Fields	Endogenous Metabolite
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-B1508R

Vitamin K4 (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite Apoptosis
Vitamin K4 (Standard) is the analytical standard of Vitamin K4. This product is intended for research and analytical applications. Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. Vitamin K4 arrests the cells in S phase and induces apoptosis. Vitamin K4 can be used for the research of cancer, such as prostate cancer and osteosarcoma .

HY-109569

Vitamin K2	Other Terpenoids Classification of Application Fields Terpenoids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Vitamin K2 is an endogenous metabolite.

HY-B0332

Menadione Maximum Cited Publications 14 Publications Verification Vitamin K3	Quinones Structural Classification Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Naphthalene Quinones Disease Research Fields	Endogenous Metabolite
Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer .

HY-B2156

Menaquinone-4 1 Publications Verification Vitamin K2(MK-4); Menaquinone K4	Quinones Structural Classification Microorganisms other families Classification of Application Fields Source classification Plants Endogenous metabolite Naphthalene Quinones Disease Research Fields Cancer	Endogenous Metabolite
Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-N0684A

*cis-Vitamin* K1** cis-Phylloquinone; cis-Phytomenadione	Cardiovascular Disease Quinones Structural Classification Classification of Application Fields Source classification Endogenous metabolite Naphthalene Quinones Disease Research Fields	Endogenous Metabolite
Cis-Vitamin K1 is an endogenous metabolite of Vitamin K .

HY-W017464

NAPQI	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Drug Metabolite Endogenous Metabolite
NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver .

HY-N6961

Lapachol 1 Publications Verification	Infection Quinones Structural Classification Classification of Application Fields Tabebuia avellanedae Plants Bignoniaceae Naphthalene Quinones Inflammation/Immunology Disease Research Fields	Dihydroorotate Dehydrogenase DNA/RNA Synthesis Parasite
Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity .

HY-N2853

D-α-Tocopherylquinone α-Tocopherylquinone	Quinones Microorganisms Classification of Application Fields Source classification Benzene Quinones Disease Research Fields Cancer	Others
D-α-Tocopherylquinone (α-Tocopherylquinone) is a quinone, can be isolated from Phaeodactylum tricornutum. D-α-Tocopherylquinone is a oxidation product of α-Tocopherol (vitamin E). D-α-Tocopherylquinone can act as an anticoagulant and as an antioxidant .

HY-W011474

Geranylgeraniol	Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

Species:	Human (4) Mouse (1)
Tag:	GFP (1) His (4) Flag (1)
Source:	HEK293 (4) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P74614

	Protein S/PROS1 Protein, Human (HEK293, His) Vitamin K-dependent protein S; PROS1; PROS	Human	HEK293
	Protein S/PROS1 Proteinas are potent antagonists of BMP4 and inhibit BMP4 by binding to BMP4 and preventing receptor interaction. This change redirects neural stem cells from gliogenesis to neurogenesis, thereby promoting the differentiation of neurons in the brain. Protein S/PROS1 Protein, Human (HEK293, His) is the recombinant human-derived protein S/PROS1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74236

	Coagulation Factor XIV/PROC Protein, Mouse (HEK293, His) Vitamin K-dependent protein C; APC; Protein C; PROC	Mouse	HEK293
	Factor XIV/PROC protein (or protein C) is an important vitamin K-dependent serine protease that regulates blood clotting. Protein C plays a crucial role in inactivating factors Va and VIIIa and regulating the coagulation cascade in the presence of calcium ions and phospholipids. Coagulation Factor XIV/PROC Protein, Mouse (HEK293, His) is the recombinant mouse-derived Coagulation Factor XIV/PROC protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor XIV/PROC Protein, Mouse (HEK293, His) is 442 a.a., with molecular weight of ~63 & 45 kDa, respectively.

HY-P74237

	Coagulation Factor XIV/PROC Protein, Human (HEK293, His) Vitamin K-dependent protein C; APC; Protein C; PROC	Human	HEK293
	Coagulation Factor XIV/PROC is a vital vitamin K-dependent serine protease regulating blood coagulation. Active Protein C inactivates factors Va and VIIIa in the presence of calcium ions and phospholipids, maintaining the intricate balance of coagulation pathways. Its protective effect on endothelial cell barrier function underscores a broader impact on vascular integrity. Coagulation Factor XIV/PROC Protein, Human (HEK293, His) is the recombinant human-derived Coagulation Factor XIV/PROC protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor XIV/PROC Protein, Human (HEK293, His) is 443 a.a., with molecular weight of 56-64 & 45 kDa, respectively.

HY-P701835

	VKOR1 Protein, Human (HEK293, GFP, His) VKORC1; Vitamin K epoxide reductase complex subunit 1; Vitamin K1 2; 3-epoxide reductase subunit 1	Human	HEK293
	As the catalytic subunit of the VKOR complex, the VKOR1 protein is crucial in vitamin K metabolism and is essential for the reduction of inactive vitamin K 2,3-epoxide to the active form. This process is critical for γ-carboxylation of proteins and is particularly important for blood coagulation and the synthesis of coagulation factors. VKOR1 Protein, Human (HEK293, GFP, His) is the recombinant human-derived VKOR1 protein, expressed by HEK293 , with C-10*His, GFP labeled tag. The total length of VKOR1 Protein, Human (HEK293, GFP, His) is 163 a.a., .

HY-P701838

	P371 Protein, Human (Sf9, FLAG) GGCX; Vitamin K-dependent gamma-carboxylase; Gamma-glutamyl carboxylase; Peptidyl-glutamate 4-carboxylase; Vitamin K gamma glutamyl carboxylase	Human	Sf9 insect cells
	The P371 protein is critical in cellular processes and mediates vitamin K-dependent carboxylation of glutamate residues to form calcium-binding γ-carboxyglutamic acid (Gla) residues. At the same time, it converts the reduced hydroquinone form of vitamin K into vitamin K epoxide. P371 Protein, Human (Sf9, FLAG) is the recombinant human-derived P371 protein, expressed by Sf9 insect cells , with C-Flag labeled tag. The total length of P371 Protein, Human (Sf9, FLAG) is 758 a.a., .

Cat. No.	Product Name	Chemical Structure

HY-N0684S

Vitamin K1-d7

Vitamin K1-d₇ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1][2].
HY-132389S

Vitamin K3-d8

Vitamin K3-d₈ is the deuterium labeled Vitamin K3[1].

HY-112499S

Menaquinone-7-d7

Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-113164S

Vitamin K1 2,3-epoxide-d7

Vitamin K1 2,3-epoxide-d₇ is the deuterium labeled Vitamin K1 2,3-epoxide[1].
HY-N0684S1

Vitamin K1-d4

Vitamin K1-d₄ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1].

HY-112499S1

Menaquinone-7-13C6

Menaquinone-7- ¹³C₆ is the ¹³C-labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-N0684S4

Vitamin K1-d3

Vitamin K1-d₃ (Phylloquinone-d₃; Phytomenadione-d₃) is deuterium-labeled Vitamin K1 (HY-N0684) .
HY-N0684S3

Vitamin K1-13C6

Vitamin K1- ¹³C₆ is the ¹³C-labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-B2156S

Menaquinone-4-d7
Menaquinone-4-d₇ (Vitamin K2(MK-4)-d7) is the deuterium labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-B0332S

Menadione-d3

Menadione-d₃ is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.

HY-B2156S1

Menaquinone-4-13C6
Menaquinone-4- ¹³C₆ is the ¹³C-labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-N0684AS

cis-Vitamin K1-d7

cis-Vitamin K1-d₇ is the deuterium labeled cis-Vitamin K1, is an endogenous metabolite of Vitamin K .
HY-B0325S

Phenindione-d5

Phenindione-d₅ is deuterium labeled Phenindione, which is an anticoagulant which functions as a Vitamin K antagonist.
HY-B1014S

Acenocoumarol-d5

Acenocoumarol-d₅ is the deuterium labeled Acenocoumarol. Acenocoumarol is an anticoagulant that functions as a Vitamin K antagonist[1][2].

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