2. Search Result
Search Result
Results for "

antibiotic+activity

" in MedChemExpress (MCE) Product Catalog:

48

Inhibitors & Agonists

4

Peptides

18

Natural
Products

4

Isotope-Labeled Compounds

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-A0088A
    Cefotaxime
    Maximum Cited Publications
    12 Publications Verification

    Cefotaxim; HR-756

    		 Beta-lactamase Bacterial Antibiotic Infection Inflammation/Immunology
    Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime
  • HY-A0088
    Cefotaxime sodium
    Maximum Cited Publications
    12 Publications Verification

    Cefotaxim sodium; HR-756 sodium

    		 Beta-lactamase Bacterial Antibiotic Infection Neurological Disease
    Cefotaxime (Cefotaxim) sodium, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime sodium
  • HY-128780B
    SPR206 acetate
    1 Publications Verification

    		 Bacterial Antibiotic Infection
    SPR206 acetate is a polymyxin analog with antibiotic activity against Gram-negative pathogens, including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacterium’s outer membrane. The MIC values of SPR206 acetate against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L .
    SPR206 acetate
  • HY-100760
    Toxoflavin
    5+ Cited Publications

    Xanthothricin; Toxoflavine; PKF-118-310

    		 β-catenin Bacterial Antibiotic Histone Demethylase Infection Cancer
    Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor and antibiotic activity .
    Toxoflavin
  • HY-B1831A
    Oritavancin diphosphate
    2 Publications Verification

    LY333328 diphosphate

    		 Bacterial Antibiotic Infection Inflammation/Immunology
    Oritavancin diphosphate (LY333328 diphosphate), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
    Oritavancin diphosphate
  • HY-133704
    Pyrrolnitrin
    1 Publications Verification

    		 Bacterial Fungal Antibiotic Infection
    Pyrrolnitrin is an antibiotic isolated from Pseudomonas pyrrocinia. Pyrrolnitrin shows a broad spectrum of antibiotic activity against fungi, yeast and gram-positive bacteria .
    Pyrrolnitrin
  • HY-P0270
    Magainin 2

    Magainin II

    		 Bacterial Antibiotic Fungal Infection
    Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .
    Magainin 2
  • HY-A0071
    Tildipirosin

    		Bacterial Antibiotic Infection
    Tildipirosin, a long-acting macrolide, has antibiotic activity.
    Tildipirosin
  • HY-P0269
    Magainin 1

    Magainin I

    		 Bacterial Fungal Antibiotic Infection
    Magainin 1 (Magainin I) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria .
    Magainin 1
  • HY-124819
    D13-9001

    		Bacterial Infection
    D13-9001 is a potent AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor with the KD values of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively . D13-9001 exhibits antibiotic activities .
    D13-9001
  • HY-130837
    JH-LPH-28

    		Bacterial Infection
    JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-28 displays outstanding antibiotic activity with a MIC value of 0.83 μg/mL .
    JH-LPH-28
  • HY-N9362
    Emodinanthrone

    EmodAN

    		 Ferroptosis Antibiotic Cardiovascular Disease Infection
    Emodinanthrone (EmodAn) is a MARCH7 stabilizer that inhibits ferroptosis (EC50=70 nM). Emodinanthrone is also a precursor to Emodin (HY-14393) and possesses antibiotic activity. Emodinanthrone directly binds to MARCH7 and blocks its ubiquitination-mediated degradation at the K608 site; this action enhances MARCH7-mediated K48 ubiquitination and degradation of NCOA4, as well as its regulation of the intracellular localization of TFR1 via K63 ubiquitination, thereby reducing the intracellular labile iron pool and blocking ferroptosis. Emodinanthrone demonstrates in vivo cardioprotective effects and exhibits a favorable safety profile. Emodinanthrone is applicable to research on ferroptosis-related cardiovascular diseases, including Doxorubicin (HY-15142A)-induced cardiomyopathy and myocardial ischemia-reperfusion injury .
    Emodinanthrone
  • HY-130838
    JH-LPH-33

    		Bacterial Infection
    JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-33 displays outstanding antibiotic activity with a MIC value of 0.66 μg/mL .
    JH-LPH-33
  • HY-N6737
    Aureothricin

    		Bacterial Antibiotic Infection
    Aureothricin is a dithiolopyrrolone (DTP) antibiotic first isolated from Streptomyces and exhibits relatively broad-spectrum antibiotic activity. Aureothricin can inhibit adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin .
    Aureothricin
  • HY-128780
    Upleganan

    SPR206

    		 Bacterial Infection Cancer
    Upleganan (SPR206), a polymyxin analogue, and shows antibiotic activity against multidrug resistant Gram-negative pathogen. The MIC values of Upleganan against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L .
    Upleganan
  • HY-A0088AR
    Cefotaxime (Standard)

    Cefotaxim (Standard); HR-756 (Standard)

    		 Beta-lactamase Reference Standards Bacterial Antibiotic Infection Inflammation/Immunology
    Cefotaxime (Standard) is the analytical standard of Cefotaxime. This product is intended for research and analytical applications. Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime (Standard)
  • HY-121922
    Dienone B

    Dibromoverongiaquinol

    		 Bacterial Infection
    Dienone B is a marine algicide with antibiotic activity against both Gram-positive and Gram-negative marine bacteria .
    Dienone B
  • HY-N6705
    Tropodithietic acid

    		Bacterial Antibiotic Infection
    Tropodithietic acid is a sulfur-containing antibiotic produced by the marine bacterium Phaeobacter inhibens. Tropodithietic acid exhibits a strong antibiotic activity against a broad spectrum of bacteria including alpha- and gammaproteobacteria, flavobacteria and actinobacteria .
    Tropodithietic acid
  • HY-122306
    Ansatrienin B

    Mycotrienin II

    		 Antibiotic Bacterial Infection Cancer
    Ansatrienin B (Mycotrienin II) is an ansamycin antibiotic isolated from Streptomyces. Ansatrienin B is active against fungi and yeasts, but inactive against bacteria.Ansatrienin B displays antitumor antibiotic activity and can be used as an ADC Toxin .
    Ansatrienin B
  • HY-W654101
    Cefotaxime-d3

    Cefotaxim-d3; HR-756-d3

    		 Isotope-Labeled Compounds Antibiotic Bacterial Infection
    Cefotaxime-d3 is the deuterium labeled Cefotaxime (HY-A0088A). Cefotaxime is the β-lactamase stable cephalosporin and the third-generation cephalosporin antibiotic. Cefotaxime possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime-d3
  • HY-B1831
    Oritavancin

    LY 333328; Orbactiv

    		 Antibiotic Bacterial Infection Inflammation/Immunology
    Oritavancin (LY 333328), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
    Oritavancin
  • HY-16035
    Alatrofloxacin

    		DNA/RNA Synthesis Antibiotic Cancer
    Alatrofloxacin, the parenteral proagent of Trovafloxacin, is a fluoronaphthyridone which contains an L-alanyl-L-alanyl salt. Alatrofloxacin functions similar to other fluoroquinolone antibiotics in that it not only has antibiotic activity to kill invading organisms by interfering with DNA synthesis, it possesses immunosuppressive activity .
    Alatrofloxacin
  • HY-A0088S
    Cefotaxime-d3 sodium

    Cefotaxim-d3 sodium; HR-756-d3 sodium

    		 Isotope-Labeled Compounds Beta-lactamase Bacterial Antibiotic Infection
    Cefotaxime-d3 (sodium) is the deuterium labeled Cefotaxime (sodium salt). Cefotaxime sodium salt, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime-d3 sodium
  • HY-A0088R
    Cefotaxime sodium (Standard)

    Cefotaxim sodium (Standard); HR-756 sodium (Standard)

    		 Beta-lactamase Reference Standards Bacterial Antibiotic Infection
    Cefotaxime (sodium) (Standard) is the analytical standard of Cefotaxime (sodium). This product is intended for research and analytical applications. Cefotaxime (Cefotaxim) sodium, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    Cefotaxime sodium (Standard)
  • HY-W087444A
    (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol

    		Bacterial Antibiotic Infection
    (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol is an active constituent of the aerial parts of Angelica sinensis. (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol significantly inhibits the growth of Aeromonas hydrophila. Anticoagulative and antibiotic activities .
    (S)-1-(4-Hydroxyphenyl)ethane-1,2-diol
  • HY-124111
    10-Deoxymethymycin

    Antibiotic YC 17

    		 Antibiotic Bacterial Infection
    10-Deoxymethymycin (Antibiotic YC 17) displays antibiotic activity against Gram positive bacteria .
    10-Deoxymethymycin
  • HY-125060
    Viridicatin

    		Antibiotic Endogenous Metabolite Infection
    Viridicatin is a fungal metabolite from Penicillium species. Viridicatin shows slight in vitro antibiotic activity against Mycobacterium tuberculosis .
    Viridicatin
  • HY-P1612
    Hormaomycin

    		Antibiotic Bacterial Infection
    Hormaomycin is a potent and selective macrocyc antibiotic agent. Hormaomycin has broad-spectrum antibiotic activity against numerous Gram-positive .
    Hormaomycin
  • HY-A0071R
    Tildipirosin (Standard)

    		Reference Standards Bacterial Antibiotic Infection
    Tildipirosin (Standard) is the analytical standard of Tildipirosin. This product is intended for research and analytical applications. Tildipirosin, a long-acting macrolide, has antibiotic activity.
    Tildipirosin (Standard)
  • HY-W742895
    Tildipirosin-d10

    		Isotope-Labeled Compounds Bacterial Infection
    Tildipirosin-d10 is the deuterium labeled Tildipirosin (HY-A0071). Tildipirosin, a long-acting?macrolide, has?antibiotic?activity .
    Tildipirosin-d10
  • HY-19584
    Variotin

    		Fungal Infection
    Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .
    Variotin
  • HY-N10273
    Deoxyfusapyrone

    		Fungal Infection
    Deoxyfusapyrone is an antifungal alpha-pyrone from Fusarium semitectum. Deoxyfusapyrone shows a strong antibiotic activity towards Geotrichum candidum in disk diffusion assays, but is not toxic to Artemia salina larvae .
    Deoxyfusapyrone
  • HY-113622
    Cladospirone bisepoxide

    Palmarumycin C13; Diepoxin ζ; Antibiotic Sch53514

    		 Fungal Antibiotic Infection
    Cladospirone bisepoxide is a metabolite that isolated from cultures of a fungus. Cladospirone bisepoxide displays selective antibiotic activity against several bacteria and fungi and inhibits germinations of Lepidium sativum at low concentrations .
    Cladospirone bisepoxide
  • HY-169175
    CN-CC-861

    		Antibiotic Bacterial Infection
    CN-CC-861 is a broad-spectrum antibiotic. CN-CC-861 shows antibiotic activities for susceptible and multidrug-resistant bacteria. CN-CC-861 shows potent bactericidal activity in vivo .
    CN-CC-861
  • HY-P0269A
    Magainin 1 TFA

    		Bacterial Fungal Antibiotic Infection
    Magainin 1 TFA (Magainin I TFA) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 TFA exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria .
    Magainin 1 TFA
  • HY-126649
    Bacillosporin C

    		Antibiotic Infection
    Bacillosporin C is an oxaphenalenone dimer originally isolated from T. bacillosporus. Bacillosporin C, an anhydride, is formed from the lactone bacillosporin D in the mangrove endophytic fungus SBE-14. Similar oxaphenalenone dimers have antibiotic activity and inhibit acetylcholinesterase.
    Bacillosporin C
  • HY-126662
    Netzahualcoyone

    		Antibiotic Bacterial Infection
    Netzahualcoyone is a triterpenoid compound isolated from the Celastraceae plant family. Netzahualcoyone exhibits broad-spectrum antibiotic activity against Gram-positive bacteria and yeasts, but is not active against Gram-negative bacteria. Netzahualcoyone can be utilized in the development of antibiotics and for studying antimicrobial mechanisms .
    Netzahualcoyone
  • HY-100760R
    Toxoflavin (Standard)

    Xanthothricin (Standard); Toxoflavine (Standard); PKF-118-310 (Standard)

    		 Reference Standards β-catenin Bacterial Antibiotic Histone Demethylase Infection Cancer
    Toxoflavin (Standard) is the analytical standard of Toxoflavin. This product is intended for research and analytical applications. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor and antibiotic activity[1][2].
    Toxoflavin (Standard)
  • HY-151944
    Antibacterial agent 128

    		Bacterial Antibiotic Infection
    Antibacterial agent 128 is a siderophore analog-Ciprofloxacin (HY-B0356) conjugate with a cleavable linker. Antibacterial agent 128 shows antibiotic activities against P. aeruginosa (MIC values of 0.25-64 μg/mL) and B. pseudomallei (MIC values of 1-32 μg/mL) .
    Antibacterial agent 128
  • HY-W701205
    4-Epitetracycline-d6

    		Isotope-Labeled Compounds Antibiotic Infection
    4-Epitetracycline-d6 is deuterated labeled 4-Epitetracycline hydrochloride (HY-136443) 4-Epitetracycline hydrochloride is an epimer of Tetracycline (HY-A0107). Tetracycline can undergo epimerization insolution to 4-Epitetracycline hydrochloride, which shows a much lower antibiotic activity.
    4-Epitetracycline-d6
  • HY-116617R
    15-Keto Travoprost (Standard)

    15-Keto Fluprostenol isopropyl ester (Standard)

    		 Drug Metabolite Reference Standards Others
    Cefotaxime (Standard) is the analytical standard of Cefotaxime. This product is intended for research and analytical applications. Cefotaxime, a β-lactamase stable cephalosporin and a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria .
    15-Keto Travoprost (Standard)
  • HY-113801R
    N-(3-Oxooctanoyl)-DL-homoserine lactone (Standard)

    (Rac)-3-oxo-C8-HSL (Standard)

    		 Endogenous Metabolite Reference Standards Metabolic Disease
    4-Epitetracycline (hydrochloride) (Standard) is the analytical standard of 4-Epitetracycline (hydrochloride). This product is intended for research and analytical applications. 4-Epitetracycline hydrochloride is an epimer of Tetracycline (HY-A0107). Tetracycline can undergo epimerization in solution to 4-Epitetracycline hydrochloride, which shows a much lower antibiotic activity .
    N-(3-Oxooctanoyl)-DL-homoserine lactone (Standard)
  • HY-128049
    ML121

    		Beta-lactamase Infection
    ML121 is a selective and potent VIM-2 inhibitor with an IC50 of 54 nM and a Ki of 148 nM. ML121 shows inactive in IMP-1 and TEM-1 beta-lactamase assays. ML121 can potentiate the antibiotic activity of Imipenem (HY-B1369A) in VIM-2 transformed E.coli .
    ML121
  • HY-130838R
    JH-LPH-33 (Standard)

    		Antibiotic Reference Standards Bacterial Infection
    JH-LPH-33 (Standard) is the analytical standard of JH-LPH-33. This product is intended for research and analytical applications. JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-33 displays outstanding antibiotic activity with a MIC value of 0.66 μg/mL[1].
    JH-LPH-33 (Standard)
  • HY-130837R
    JH-LPH-28 (Standard)

    		Antibiotic Reference Standards Bacterial Infection
    JH-LPH-28 (Standard) is the analytical standard of JH-LPH-28. This product is intended for research and analytical applications. JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-28 displays outstanding antibiotic activity with a MIC value of 0.83 μg/mL[1].
    JH-LPH-28 (Standard)
  • HY-13766A
    Timcodar mesylate

    VX-853-2

    		 Bacterial Others
    Timcodar mesylate (VX-853-2) and its analog VX-710 are mammalian multidrug-resistant bacterial efflux pump inhibitors that directly inhibit ethidium bromide efflux in Staphylococcus aureus. Timcodar mesylate has the potential to enhance antibiotic activity by inhibiting bacterial efflux pumps, effectively reducing the minimum inhibitory concentration of some antibiotics against Gram-positive pathogens such as Staphylococcus aureus, Enterococcus and Streptococcus pneumoniae .
    Timcodar mesylate
  • HY-B1831AR
    Oritavancin diphosphate (Standard)

    LY333328 diphosphate (Standard)

    		 Reference Standards Bacterial Antibiotic Infection Inflammation/Immunology
    Oritavancin (diphosphate) (Standard) is the analytical standard of Oritavancin (diphosphate). Oritavancin diphosphate (Standard), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate (Standard) shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate (Standard) inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate (Standard) inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate (Standard) enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .
    Oritavancin diphosphate (Standard)
  • HY-N9362R
    Emodinanthrone (Standard)

    EmodAN (Standard)

    		 Reference Standards Antibiotic Ferroptosis Infection
    Pro-xylane (Standard) is the analytical standard of Pro-xylane. This product is intended for research and analytical applications. Emodinanthrone (EmodAn) is a MARCH7 stabilizer that inhibits ferroptosis (EC50=70 nM). Emodinanthrone is also a precursor to Emodin (HY-14393) and possesses antibiotic activity. Emodinanthrone directly binds to MARCH7 and blocks its ubiquitination-mediated degradation at the K608 site; this action enhances MARCH7-mediated K48 ubiquitination and degradation of NCOA4, as well as its regulation of the intracellular localization of TFR1 via K63 ubiquitination, thereby reducing the intracellular labile iron pool and blocking ferroptosis. Emodinanthrone demonstrates in vivo cardioprotective effects and exhibits a favorable safety profile. Emodinanthrone is applicable to research on ferroptosis-related cardiovascular diseases, including Doxorubicin (HY-15142A)-induced cardiomyopathy and myocardial ischemia-reperfusion injury .
    Emodinanthrone (Standard)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: