Cladospirone bisepoxide
Cladospirone bisepoxide is a metabolite that isolated from cultures of a fungus. Cladospirone bisepoxide displays selective antibiotic activity against several bacteria and fungi and inhibits germinations of Lepidium sativum at low concentrations.
For research use only. We do not sell to patients.
- CAS No.: 152607-03-9
- Formula: C20H14O7
- Molecular Weight:366.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
>10 μM
Compound: 13
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Cytotoxicity against human A2780 cells by MTT assay
Cytotoxicity against human A2780 cells by MTT assay
|
[PMID: 25237727] |
| A549 | IC50 |
8.8 μM
Compound: 13
|
Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
|
[PMID: 25237727] |
| Bel-7402 | IC50 |
5.1 μM
Compound: 13
|
Cytotoxicity against human Bel7402 cells by MTT assay
Cytotoxicity against human Bel7402 cells by MTT assay
|
[PMID: 25237727] |
| BGC-823 | IC50 |
>10 μM
Compound: 13
|
Cytotoxicity against human BGC823 cells by MTT assay
Cytotoxicity against human BGC823 cells by MTT assay
|
[PMID: 25237727] |
| HCT-8 | IC50 |
>10 μM
Compound: 13
|
Cytotoxicity against human HCT8 cells by MTT assay
Cytotoxicity against human HCT8 cells by MTT assay
|
[PMID: 25237727] |
| MCF7 | IC50 |
1.5 μM
Compound: Diepoxin, Sigma, SCH-49209
|
Ability to inhibit the growth of MCF-7 cell line
Ability to inhibit the growth of MCF-7 cell line
|
[PMID: 11551767] |
| MDA-MB-231 | IC50 |
2 μM
Compound: Diepoxin, Sigma, SCH-49209
|
Ability to inhibit the growth of MDA-MB-231 cell line
Ability to inhibit the growth of MDA-MB-231 cell line
|
[PMID: 11551767] |
Chemical Information
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CAS No. 152607-03-9
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Molecular Weight 366.32
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Formula C20H14O7
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SMILES
O=C1C=C[C@H](O)[C@]23[C@@H](O)[C@]4([H])[C@@](C5(OC6=CC=CC7=C6C(O5)=CC=C7)[C@]12O3)([H])O4
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Synonyms
Palmarumycin C13; Diepoxin ζ; Antibiotic Sch53514
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Structure Classification
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Initial Source
fungal
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)