2. Anti-infection
  3. Bacterial
  4. Dienone B

Dienone B  (Synonyms: Dibromoverongiaquinol)

Cat. No.: HY-121922 Purity: 97.15%
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Dienone B is a marine algicide with antibiotic activity against both Gram-positive and Gram-negative marine bacteria.

For research use only. We do not sell to patients.

Dienone B

Dienone B Chemical Structure

CAS No. : 17194-81-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg   Get quote  
200 mg   Get quote  

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Dienone B Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Dienone B is a marine algicide with antibiotic activity against both Gram-positive and Gram-negative marine bacteria[1].

Cellular Effect
Cell Line Type Value Description References
HeLa S3 IC50
1.5 μM
Compound: 2
Dose enhancement factor, ratio of IC50 for human HeLaS3 cells after 4 days to IC50 for buthionine sulfoximine-pretreated human HeLaS3 cells after 4 days by MTT assay
Dose enhancement factor, ratio of IC50 for human HeLaS3 cells after 4 days to IC50 for buthionine sulfoximine-pretreated human HeLaS3 cells after 4 days by MTT assay
[PMID: 8786366]
HeLa S3 IC50
10.4 μM
Compound: 2
Cytotoxicity against buthionine sulfoximine-pretreated human HeLaS3 cells after 4 days by MTT assay
Cytotoxicity against buthionine sulfoximine-pretreated human HeLaS3 cells after 4 days by MTT assay
[PMID: 8786366]
HeLa S3 IC50
15.6 μM
Compound: 2
Cytotoxicity against human HeLaS3 cells after 4 days by MTT assay
Cytotoxicity against human HeLaS3 cells after 4 days by MTT assay
[PMID: 8786366]
HeLa S3 IC50
15.7 μM
Compound: 2
Cytotoxicity against buthionine sulfoximine-pretreated human HeLaS3 cells after 2 hrs by MTT assay
Cytotoxicity against buthionine sulfoximine-pretreated human HeLaS3 cells after 2 hrs by MTT assay
[PMID: 8786366]
HeLa S3 IC50
2 μM
Compound: 2
Dose enhancement factor, ratio of IC50 for human HeLaS3 cells after 2 hrs to IC50 for buthionine sulfoximine-pretreated human HeLaS3 cells after 2 hrs by MTT assay
Dose enhancement factor, ratio of IC50 for human HeLaS3 cells after 2 hrs to IC50 for buthionine sulfoximine-pretreated human HeLaS3 cells after 2 hrs by MTT assay
[PMID: 8786366]
HeLa S3 IC50
31.9 μM
Compound: 2
Cytotoxicity against human HeLaS3 cells after 2 hrs by MTT assay
Cytotoxicity against human HeLaS3 cells after 2 hrs by MTT assay
[PMID: 8786366]
HeLa S3 IC50
58 μM
Compound: 2
Cytotoxicity against human HeLaS3 cells after 2 weeks by clonogenic assay
Cytotoxicity against human HeLaS3 cells after 2 weeks by clonogenic assay
[PMID: 8786366]
Molecular Weight

324.95

Formula

C8H7Br2NO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CC1(C=C(C(C(Br)=C1)=O)Br)O)N
Initial Source

Verongia aerophoba
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (76.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0774 mL 15.3870 mL 30.7740 mL
5 mM 0.6155 mL 3.0774 mL 6.1548 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0774 mL 15.3870 mL 30.7740 mL 76.9349 mL
5 mM 0.6155 mL 3.0774 mL 6.1548 mL 15.3870 mL
10 mM 0.3077 mL 1.5387 mL 3.0774 mL 7.6935 mL
15 mM 0.2052 mL 1.0258 mL 2.0516 mL 5.1290 mL
20 mM 0.1539 mL 0.7693 mL 1.5387 mL 3.8467 mL
25 mM 0.1231 mL 0.6155 mL 1.2310 mL 3.0774 mL
30 mM 0.1026 mL 0.5129 mL 1.0258 mL 2.5645 mL
40 mM 0.0769 mL 0.3847 mL 0.7693 mL 1.9234 mL
50 mM 0.0615 mL 0.3077 mL 0.6155 mL 1.5387 mL
60 mM 0.0513 mL 0.2564 mL 0.5129 mL 1.2822 mL
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Dienone B Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dienone B17194-81-9DibromoverongiaquinolBacterialInhibitorinhibitorinhibit

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