1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Cefotaxime

Cefotaxime (Synonyms: Cefotaxim; HR-756)

Cat. No.: HY-A0088A
Handling Instructions

Cefotaxime, a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria.

For research use only. We do not sell to patients.

Cefotaxime Chemical Structure

Cefotaxime Chemical Structure

CAS No. : 63527-52-6

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Description

Cefotaxime, a third-generation cephalosporin antibiotic, possesses broad-spectrum antibiotic activity against numerous Gram-positive and Gram-negative bacteria[1][2][3][4].

In Vitro

Cefotaxime exhibits an MIC of 0.0625 mg/L for V. vulnificus CMCP6[4].

In Vivo

The combination of ciprofloxacin and cefotaxime is more effective in clearing V. vulnificus in vivo than previously used regimens[4].

Animal Model: Female, specific pathogen free, 8-week-old BALB/c mice[4].
Dosage: 30 mg/kg.
Administration: IP every 6 h.
Result: The viable bacterial counts in liver were lower in mice treated with cefotaxime-plus-ciprofloxacin than in those treated with cefotaxime alone (P<0.001 at 24 h and 48 h, each).
Molecular Weight

455.47

Formula

C₁₆H₁₇N₅O₇S₂

CAS No.

63527-52-6

SMILES

O=C(C(N12)=C(COC(C)=O)CS[[email protected]]2([H])[[email protected]](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CefotaximeCefotaximHR-756HR756HR 756BacterialAntibioticInhibitorinhibitorinhibit

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