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cell-impermeant

" in MedChemExpress (MCE) Product Catalog:

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製品番号 製品名 Target 研究分野 構造式
  • HY-D0861
    EGTA
    20+ Cited Publications

    Biochemical Assay Reagents Inflammation/Immunology
    EGTA is a cell-impermeant specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca 2+ over Mg 2+ (Mg 2+ Kd 1-10 mM). EGTA significantly inhibits the substrate adherence capacity of inflammatory macrophages .
    EGTA
  • HY-111496
    Sulfo-NHS-SS-Biotin sodium
    4 Publications Verification

    Biochemical Assay Reagents Others
    Sulfo-NHS-SS-biotin sodium is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin sodium can be used for the labeling and purifying of cell-surface protein .
    Sulfo-NHS-SS-Biotin sodium
  • HY-100168
    BAPTA
    Maximum Cited Publications
    36 Publications Verification

    Phospholipase Others
    BAPTA is a selective and cell-impermeant chelator for calcium. BAPTA has high selectivity against magnesium and calcium. BAPTA can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
    BAPTA
  • HY-D1020
    7-Aminoactinomycin D
    Maximum Cited Publications
    8 Publications Verification

    7-AAD

    DNA/RNA Synthesis Bacterial DNA Stain Antibiotic Infection Cancer
    7-Aminoactinomycin D (7-AAD) a cell-impermeant fluorescent DNA stain, is a potent RNA polymerase inhibitor. 7-Aminoactinomycin D selectively binds to GC regions of the DNA. 7-Aminoactinomycin D also has antibacterial effects .
    7-Aminoactinomycin D
  • HY-D0023
    Pyranine
    2 Publications Verification

    HPTS; Solvent Green 7

    Environmental Pollutants Fluorescent Dye Others
    Pyranine (HPTS; Solvent Green 7) is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine acts as a class of fluorescent chemosensor for the Cu + ion. Pyranine is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .
    Pyranine
  • HY-101882
    BCECF
    3 Publications Verification

    2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein

    Fluorescent Dye Others
    BCECF is a cell-impermeant pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
    BCECF
  • HY-100168A
    BAPTA tetrasodium
    Maximum Cited Publications
    36 Publications Verification

    Phospholipase Others
    BAPTA tetrasodium is a selective and cell-impermeant chelator for calcium. BAPTA tetrasodium has high selectivity against magnesium and calcium. BAPTA can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
    BAPTA tetrasodium
  • HY-126774
    DAF-FM
    1 Publications Verification

    Fluorescent Dye Others
    DAF-FM is a cell-impermeant diaminofluorescein, which can be used as fluorescent indicator for nitric oxide (NO) with good pH tolerance .
    DAF-FM
  • HY-D0861A
    EGTA tetrasodium
    20+ Cited Publications

    Biochemical Assay Reagents Inflammation/Immunology
    EGTA tetrasodium is a cell-impermeant specific calcium ion chelator. EGTA tetrasodium has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca 2+ over Mg 2+ (Mg 2+ Kd 1-10 mM). EGTA tetrasodium significantly inhibits the substrate adherence capacity of inflammatory macrophages .
    EGTA tetrasodium
  • HY-117070

    Fluorescent Dye Others
    TO-PRO-3 iodide is a cell-impermeant nucleic acid stain. TO-PRO-3 iodide is useful as a nuclear counterstain and dead cell indicator (Ex/Em = 642/661 nm).
    TO-PRO-3 iodide
  • HY-100168B
    BAPTA tetrapotassium
    Maximum Cited Publications
    36 Publications Verification

    Phospholipase Others
    BAPTA tetrapotassium is a selective and cell-impermeant chelator for calcium. BAPTA has high selectivity against magnesium and calcium. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
    BAPTA tetrapotassium
  • HY-D1444
    Propidium monoazide
    1 Publications Verification

    Fluorescent Dye Bacterial Infection
    Propidium monoazide is a cell-impermeant photoreactive DNA-binding dye that preferentially binds to dsDNA. Propidium monoazide (PMA) prevents DNA from dead bacteria from being amplified during the PCR. PMA-PCR enhanced both the specificity and the sensitivity of PCR . Propidium monoazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Propidium monoazide
  • HY-D0982

    Fluorescent Dye Others
    Zinquin is a cell-impermeant fluorescent sensor and used to observe reactive Zn 2+. λex/λem=368/490 nm.
    Zinquin
  • HY-139646

    Fluorescent Dye Neurological Disease
    KMG-104 is a cell-impermeant highly selective fluorescent Mg 2+ probe. KMG-104 has been used widely and revealed Mg 2+ mobilization in cytoplasm in various types of cells .
    KMG-104
  • HY-D1436

    Fluorescent Dye Neurological Disease
    PBFI is the cell-impermeant fluorescent indicator that is widely used for the determination of concentrations of K + (Ex/Em = 340,380/500 nm) .
    PBFI
  • HY-D1760

    Fluorescent Dye Others
    SBFI is a cell-impermeant, fluorescent Na + indicator dye. SBFI is excited at 340 nm and the fluorophore emission is collected at 450 nm . SBFI selective for Na + over K + with Kd values of 20 and 120 mM for these ions, respectively. .
    Sodium-binding benzofuran isophthalate
  • HY-D1702

    Fluorescent Dye Others
    Mag-Fura-2 tetrapotassium is a cell-impermeant UV excitable rational fluorescent Mg 2+/Ca 2+ indicator (Ex=334-360 nm, Em=510 nm). Mag-Fura-2 tetrapotassium can be used for the determination of Mg 2+ and Ca 2+ concentrations .
    Mag-Fura-2 tetrapotassium
  • HY-D2208
    SYTM Green
    1 Publications Verification

    Fluorescent Dye Others
    SYTM Green is a cell impermeant DNA dye that fluoresces green by binding to dsDNA (Ex/Em=503/530 nm). SYTM Green can also be used to stain bacteria, including Gram-positive and Gram-negative bacteria. Note: SYTM Green cannot penetrate living cells, and this product is equivalent to (Ex/Em=488/530 nm) .
    SYTM Green
  • HY-D1631A

    Fluorescent Dye Neurological Disease
    Calcium green-5N hexapotassium is a cell-impermeant Ca 2+-sensitive fluorescent probe. Calcium green-5N hexapotassium shows enhancement in fluorescence intensity on binding Ca 2+, and can monitor free Ca 2+ in neurons .
    Calcium green-5N hexapotassium
  • HY-D1442

    Fluorescent Dye Others
    SBFI (tetraammonium), the tetraammonium salt of SBFI, is a cell-impermeant sodium fluorescence indicator. SBFI (tetraammonium) is sodium-sensitive dye. The excitation wavelength is set 333 nm, and the emission wavelength is 539 nm for SBFI .
    SBFI tetraammonium
  • HY-D0121

    Fluorescent Dye Others
    INDO 1 is a cell-impermeant fluorescent Ca 2+ indicator, binds specifically to Ca 2+ while emitting fluorescence, the maximum emission wavelength shifts from 485 nm before binding to 410 nm .
    INDO 1
  • HY-W127781

    Fluorescent Dye Others
    Rhod-2 triammonium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 triammonium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .
    Rhod-2 triammonium
  • HY-172627

    Fluorescent Dye Calcium Channel Others
    Rhod-FF tripotassium is a Rhod-2 derivative and cell-impermeant calcium indicator (Kd of 320 μM). Rhod-FF tripotassium indicates calcium concentration by fluorescence upon binding to calcium ions, with excitation at 552 nm and emission at 580 nm .
    Rhod-FF tripotassium
  • HY-136894

    Fluorescent Dye Others
    Rhod-5N is a cell-impermeant calcium-binding fluorescent dye composed of a BAPTA chelating group and a rhodamine fluorophore. Rhod-5N is often added to MOPS buffer to complex and indicate cation content. The selectivity of Rhod-5N for Cd 2+ is higher than other interfering cations ((Na+, K+, Mg 2+, Ca 2+, Zn 2+) except Pb 2+), and the detection limit is 3.1 μg/L .
    Rhod-5N
  • HY-D1779

    Fluorescent Dye Others
    Fura-5F pentapotassium is a cell-impermeant fluorescent calcium indicator.
    Fura-5F pentapotassium
  • HY-D1761

    Fluorescent Dye Others
    Fura-4F pentapotassium is a cell-impermeant fluorescent indicator for intracellular calcium ion measurement.
    Fura-4F pentapotassium
  • HY-176031

    Fluorescent Dye Others
    Fluo-2 potassium is a cell-impermeant fluorescent calcium indicator. Fluo-2 potassium binds calcium (Kd: 0.37 μM) with excitation/emission wavelengths of 493/518 nm, respectively .
    Fluo-2 potassium
  • HY-D0121A

    Fluorescent Dye Others
    INDO 1 pentapotassium is a cell-impermeant fluorescent Ca 2+ indicator, binds specifically to Ca 2+ while emitting fluorescence, the maximum emission wavelength shifts from 485 nm before binding to 410 nm .
    INDO 1 pentapotassium
  • HY-137128

    Fluorescent Dye Others
    BTC tetrapotassium is a cell-impermeant calcium indicator (Kd approximately 7-26 µM) featuring many desirable properties for cellular calcium imaging, including long excitation wavelengths (400/485 nm), low sensitivity to Mg 2+, and accuracy of ratiometric measurement .
    BTC tetrapotassium
  • HY-D0023A

    HPTS hydrate; Solvent Green 7 hydrate

    Fluorescent Dye Others
    Pyranine (HPTS; Solvent Green 7) hydrate is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine hydrate acts as a class of fluorescent chemosensor for the Cu + ion. Pyranine hydrate is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .
    Pyranine hydrate
  • HY-D1447

    Fluorescent Dye Others
    Fluo-3FF pentapotassium is a cell-impermeant fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds=42 and 0.4 μM, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations.
    Fluo-3FF pentapotassium
  • HY-100168R

    Reference Standards Phospholipase Others
    BAPTA (Standard) is the analytical standard of BAPTA. This product is intended for research and analytical applications. BBAPTA is a selective and cell-impermeant chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca 2+ release from intracellular stores or influx via Ca 2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
    BAPTA (Standard)
  • HY-D0121B

    Fluorescent Dye Others
    INDO 1 pentasodium is a cell-impermeant ratiometric, free calcium ion (Ca 2+) fluorescent indicator that can quantitatively monitor dynamic changes in intracellular free Ca 2+ concentrations. When unbound to Ca 2+ (free state), INDO 1 pentasodium exhibits a peak emission wavelength of 485 nm under UV excitation (350 nm). Upon binding to Ca 2+ (bound state), the emission peak shifts to 405 nm. INDO 1 pentasodium is highly photolabile and susceptible to photobleaching, and its emission spectrum may overlap with the autofluorescence of NADH .
    INDO 1 pentasodium
  • HY-100168AR

    Reference Standards Phospholipase Others
    BAPTA tetrasodium (Standard) is the analytical standard of BAPTA tetrasodium. This product is intended for research and analytical applications. BAPTA tetrasodium is a selective and cell-impermeant chelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca 2+ release from intracellular stores or influx via Ca 2+-permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
    BAPTA tetrasodium (Standard)
  • HY-136784A

    Fluorescent Dye Others
    Rhod-2 sodium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 sodium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .
    Rhod-2 sodium
  • HY-136784

    Fluorescent Dye Others
    Rhod-2 potassium is a cell impermeant, red fluorescent calcium indicator. Rhod-2 potassium exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators Fura-2 and Indo-1 (HY-D0121), there is no accompanying spectral shift .
    Rhod-2 potassium
  • HY-DY1083

    Fluorescent Dye Others
    Zinquin (solution) is a cell-impermeant fluorescent sensor and used to observe reactive Zn 2+. λex/λem=368/490 nm.
    Solvent and concentration: DMSO: 5 mM
    Zinquin (solution)
  • HY-W778574

    Phospholipase Cardiovascular Disease Others Neurological Disease
    BAPTA tetracesium is a selective and cell-impermeant chelator for calcium. BAPTA tetracesium has high selectivity against magnesium and calcium. BAPTA tetracesium can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
    BAPTA tetracesium
  • HY-DY1099

    7-AAD (solution)

    DNA/RNA Synthesis DNA Stain Bacterial Antibiotic Cancer
    7-Aminoactinomycin D (solution) (7-AAD (solution)) a cell-impermeant fluorescent DNA stain, is a potent RNA polymerase inhibitor. 7-Aminoactinomycin D selectively binds to GC regions of the DNA. 7-Aminoactinomycin D also has antibacterial effects .
    Solvent and concentration: DMSO: 1 mg/mL
    7-Aminoactinomycin D (solution)
  • HY-DY1098

    2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein (solution)

    Fluorescent Dye Others
    BCECF (solution) (2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein (solution)) is a cell-impermeant pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm.
    Solvent and concentration: DMSO: 10 mM
    BCECF (solution)
  • HY-100168BR

    Reference Standards Phospholipase Others
    BAPTA tetrapotassium (Standard) is the analytical standard of BAPTA tetrapotassium (HY-100168B). This product is intended for research and analytical applications. BAPTA tetrapotassium is a selective and cell-impermeant chelator for calcium. BAPTA tetrapotassium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca 2+ release from intracellular stores or influx via Ca 2+-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators .
    BAPTA tetrapotassium (Standard)
  • HY-D3239

    AF405; Alexa Fluor 405 succinimidyl ester

    Fluorescent Dye OAT Others
    AF405 NHS Ester (AF405) is a Fluorescent probe substrate, as well as a substrate for OATP1B1, OATP1B3 and OATP2B1 .
    AF405 NHS Ester

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