1. Metabolic Enzyme/Protease
  2. Phospholipase
  3. BAPTA tetrasodium

BAPTA tetrasodium is a selective chelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators.

For research use only. We do not sell to patients.

BAPTA tetrasodium Chemical Structure

BAPTA tetrasodium Chemical Structure

CAS No. : 126824-24-6

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 50 In-stock
Solution
10 mM * 1 mL in Water USD 50 In-stock
Solid
5 mg USD 40 In-stock
10 mg USD 50 In-stock
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Based on 21 publication(s) in Google Scholar

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Description

BAPTA tetrasodium is a selective chelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2][3].

In Vitro

BAPTA (0.3-30 μM; 1 h) can be used for the prevention of [Ca2+]-induced cell damage, but disturbe calcium signalling in isingle differentiated NH15-CA2 neuroblastoma and glioma hybrid cells[3].
BAPTA (0-10 mM) inhibits phospholipase C (PLC) activity in a dose-dependent manner, and is unrelated to Ca2+[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

564.36

Formula

C22H20N2Na4O10

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O[Na])CN(C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(O[Na])=O)CC(O[Na])=O)CC(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (177.19 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7719 mL 8.8596 mL 17.7192 mL
5 mM 0.3544 mL 1.7719 mL 3.5438 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7719 mL 8.8596 mL 17.7192 mL 44.2980 mL
5 mM 0.3544 mL 1.7719 mL 3.5438 mL 8.8596 mL
10 mM 0.1772 mL 0.8860 mL 1.7719 mL 4.4298 mL
15 mM 0.1181 mL 0.5906 mL 1.1813 mL 2.9532 mL
20 mM 0.0886 mL 0.4430 mL 0.8860 mL 2.2149 mL
25 mM 0.0709 mL 0.3544 mL 0.7088 mL 1.7719 mL
30 mM 0.0591 mL 0.2953 mL 0.5906 mL 1.4766 mL
40 mM 0.0443 mL 0.2215 mL 0.4430 mL 1.1074 mL
50 mM 0.0354 mL 0.1772 mL 0.3544 mL 0.8860 mL
60 mM 0.0295 mL 0.1477 mL 0.2953 mL 0.7383 mL
80 mM 0.0221 mL 0.1107 mL 0.2215 mL 0.5537 mL
100 mM 0.0177 mL 0.0886 mL 0.1772 mL 0.4430 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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BAPTA tetrasodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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BAPTA tetrasodium
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HY-100168A
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