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Cat. No.: HY-D3239

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AF405 NHS Ester

(Synonyms: AF405; Alexa Fluor 405 succinimidyl ester)

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

AF405 NHS Ester (AF405) is a Fluorescent probe substrate, as well as a substrate for OATP1B1, OATP1B3 and OATP2B1.

For research use only. We do not sell to patients.

Formula: C₄₆H₆₉N₅O₁₅S₃
Molecular Weight:1028.26

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Please store the product under the recommended conditions in the Certificate of Analysis.

AF405 NHS Ester Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

AF405 NHS Ester (AF405) is a Fluorescent probe substrate, as well as a substrate for OATP1B1, OATP1B3 and OATP2B1^[1].

Chemical Information

Molecular Weight 1028.26
Formula C₄₆H₆₉N₅O₁₅S₃
SMILES

CCN(CC)CC.CCN(CC)CC.CCN(CC)CC.O=S(C1=C(C2=C34)C=CC4=C(OCC(N5CCC(C(ON6C(CCC6=O)=O)=O)CC5)=O)C=C(S(=O)(O)=O)C3=CC=C2C(S(=O)(O)=O)=C1)(O)=O
Synonyms

AF405; Alexa Fluor 405 succinimidyl ester
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Small

Protein Corona Reprograms Hepatic Clearance Pathways of Biomimetic Nanoparticles via Ligand Masking and Differential Protein Enrichment. [Abstract]

2026 May;22(29):e73301. PMID: 41944292

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Patik I, et al. Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1. Sci Rep. 2018 Feb 8;8(1):2630. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

AF405 NHS Ester

1 Cited Publications

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Chemical Information
Publications (1)
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AF405 NHS Ester

Publications Citing Use of MedChemExpress (MCE) AF405 NHS Ester

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

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AF405 NHS Ester Related Classifications

HY-D3239 Related Classifications