Search Result

Results for "

lysyl

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Lysyl Oxidase (1) Akt (1) Amino Acid Derivatives (3) Aminoacyl-tRNA Synthetase (4) Bacterial (2) Biochemical Assay Reagents (4) Bradykinin Receptor (1) Collagen (1) Cytochrome P450 (1) Drug Derivative (1) Drug Intermediate (3) EGFR (1) Endogenous Metabolite (3) Fluorescent Dye (1) Guanylate Cyclase (1) MMP (1) Monoamine Oxidase (23) Nucleoside Antimetabolite/Analog (1) Parasite (2) PKG (1) Ras (1) Reference Standards (2) TGF-beta/Smad (1) TGF-β Receptor (1)
By Research Areas:	Cancer (13) Cardiovascular Disease (5) Endocrinology (1) Infection (6) Inflammation/Immunology (12) Metabolic Disease (4)
Oligonucleotides:	Phospholipids (2)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: Lysyl Oxidase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1750

β-Aminopropionitrile 10+ Cited Publications BAPN	Monoamine Oxidase Endogenous Metabolite	Metabolic Disease Cancer
β-Aminopropionitrile (BAPN) is a specific, irreversible and orally active lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile targets the active site of LOX or LOXL isoenzymes .

HY-138625A

PXS-5505 anhydrous 2 Publications Verification LOX-IN-3 dihydrochloride	Monoamine Oxidase	Cancer
PXS-5505 anhydrous (LOX-IN-3 dihydrochloride) is an orally active lysyl oxidase (LOX) inhibitor. PXS-5505 anhydrous can be used for fibrosis, cancer and angiogenesis research .

HY-138625

PXS-5505 free base 2 Publications Verification LOX-IN-3	Monoamine Oxidase	Cancer
PXS-5505 free base (LOX-IN-3) is an orally active lysyl oxidase (LOX) inhibitor. PXS-5505 free base can be used for fibrosis, cancer and angiogenesis research .

HY-107422

Lenumlostat 3 Publications Verification PAT-1251; GB2064	Monoamine Oxidase	Inflammation/Immunology
PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC₅₀s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC₅₀s, 0.10, 0.12, and 0.16 μM, respectively); PAT-1251 is used in the research of fibrotic diseases .

HY-P3205

Lysyl endopeptidase, Achromobacter sp 1 Publications Verification Lys-C	Biochemical Assay Reagents	Others
Lysyl endopeptidase, Achromobacter sp (Lys-C) catalyzes carboxyl oxygen exchange reaction. Lysyl endopeptidase has higher substrate binding affinities and higher catalytic rates at the acidic pHs than at the alkaline pHs .

HY-130242

PXS-5120A	Monoamine Oxidase	Inflammation/Immunology
PXS-5120A is a potent, irreversible fluoroallylamine inhibitor of Lysyl Oxidase-like 2/3 (LOXL2/3) with anti-fibrotic activity. PXS-5120A is >300-fold selective for LOXL2 (K_i of 83 nM; pIC₅₀ of 8.4) over LOXL (pIC₅₀ of 5.8) .

HY-P99047

Simtuzumab AB 0024; GS 6624	Monoamine Oxidase	Cardiovascular Disease Inflammation/Immunology
Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2). Simtuzumab non-competitively blocks collagen cross-linking, reduces LOXL2 protein expression and attenuates extracellular matrix changes. Simtuzumab reduces myocardial fibrosis and prevents cardiac dysfunction. Simtuzumab lowers Myh7 and Nppa gene expression, reduces contraction heterogeneity, and cuts COL1A1 deposition. Simtuzumab can be used for the research of LMNA mutation-induced dilated cardiomyopathy, idiopathic pulmonary fibrosis, and primary sclerosing cholangitis .

HY-170422

*18:1 Lysyl* PG** lysyl-DOPG	Biochemical Assay Reagents	Infection
18:1 Lysyl PG (Lysyl-DOPG) is a cationic phospholipid contains a lysine group and a DOPG .

HY-126130

LysRs-IN-2 1 Publications Verification	Aminoacyl-tRNA Synthetase	Infection
LysRs-IN-2 is a lysyl-tRNA synthetase (KRS) inhibitor with IC₅₀s of 0.015 μM and 0.13 μM for Plasmodium falciparum lysyl-tRNA synthetase (PfKRS) and Cryptosporidium parvum lysyl-tRNA synthetase (CpKRS), respectively .

HY-114286A

PXS-5153A monohydrochloride 1 Publications Verification	Monoamine Oxidase	Inflammation/Immunology
PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC₅₀ of <40 nM for LOXL2 across all mammalian species and an IC₅₀ of 63 nM for human LOXL3. PXS-5153A monohydrochloride could reduce crosslinks and ameliorates fibrosis.

HY-151499A

PXS-6302 hydrochloride	Monoamine Oxidase	Inflammation/Immunology
PXS-6302 hydrochloride is an irreversible lysyl oxidase inhibitor with IC₅₀s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 hydrochloride has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance .

HY-149597

Lysyl hydroxylase 2-IN-1	Monoamine Oxidase	Cancer
Lysyl hydroxylase 2-IN-1 (compound 12) is a selective lysyl hydroxylase 2 (LH2) Inhibitor with an IC₅₀ of ~300 nM. Lysyl hydroxylase 2-IN-1 demonstrates selectivity for LH2 over LH1 and LH3 .

HY-114788

Lysylcysteine L-lysyl-L-cysteine; Lys-Cys; H-Lys-Cys-OH	Amino Acid Derivatives	Others
Lysylcysteine (L-Lysyl-L-cysteine) is a dipeptide composed of lysine and cysteine.

HY-170538

SNT-5382	Lysyl Oxidase Cytochrome P450	Cardiovascular Disease Metabolic Disease
SNT-5382 is a lysyl oxidase family (LOX) inhibitor and anti-fibrotic agent. SNT-5382 binds to the LTQ cofactor of LOXL2 and inhibits the enzymatic activities of LOXL3, LOXL4, LOXL1, CYP2C9, and CYP2C19. SNT-5382 reduces cardiac and liver fibrosis as well as collagen crosslinks, and improves cardiac function. SNT-5382 can be used for the research of heart failure, myocardial infarction, and nonalcoholic steatohepatitis-related liver fibrosis .

HY-151499

PXS-6302	Monoamine Oxidase	Others
PXS-6302 is an irreversible lysyl oxidase inhibitor with IC₅₀s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance .

HY-170573A

LOXL2-IN-1 tosylate	Monoamine Oxidase	Cancer
LOX-IN-5 tosylate (compound 22) is a selective and orally active lysyl oxidase-like 2 (LOXL2) inhibitor with an IC₅₀ of <300 nM. LOX-IN-5 tosylate possess anti-fibrosis properties .

HY-Y1750A

β-Aminopropionitrile hydrochloride 10+ Cited Publications BAPN hydrochloride	Monoamine Oxidase Endogenous Metabolite	Metabolic Disease Cancer
β-Aminopropionitrile (BAPN) hydrochloride is a specific, irreversible and orally active lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile hydrochloride targets the active site of LOX or LOXL isoenzymes .

HY-103280

LysRs-IN-1	Aminoacyl-tRNA Synthetase	Others
LysRs-IN-1 is a Lysyl-tRNA synthetase (LysRs) inhibitor.

HY-151498A

PXS-4787 hydrochloride	Monoamine Oxidase	Others
PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 hydrochloride inhibits LOX with IC₅₀s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively. PXS-4787 hydrochloride reduces deposition and crosslinking of collagen I secreted by human fibroblasts .

HY-124674A

CCT365623 hydrochloride 1 Publications Verification	Monoamine Oxidase EGFR Akt TGF-beta/Smad	Cancer
CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor, with an IC₅₀ of 0.89 μM. CCT365623 hydrochloride suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. CCT365623 hydrochloride is extremely well tolerated, and has good pharmacokinetic properties .

HY-114286

PXS-5153A	Monoamine Oxidase	Inflammation/Immunology
PXS-5153A is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC₅₀ of <40 nM for LOXL2 across all mammalian species and an IC₅₀ of 63 nM for human LOXL3. PXS-5153A could reduce crosslinks and ameliorates fibrosis.

HY-W010789

*L-Lysyl-L-tyrosine-α-L-lysine* H-Lys-Tyr-Lys-OH; Lys-Tyr-Lys	Amino Acid Derivatives	Others
L-Lysyl-L-tyrosine-α-L-lysine is a lysine derivative .

HY-114788A

Lysylcysteine TFA L-lysyl-L-cysteine TFA; Lys-Cys TFA; H-Lys-Cys-OH TFA	Amino Acid Derivatives	Others
Lysylcysteine (L-Lysyl-L-cysteine) TFA is a dipeptide composed of lysine and cysteine .

HY-151498

PXS-4787	Monoamine Oxidase	Others
PXS-4787 is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 inhibits LOX with IC₅₀s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively .

HY-15782

YH16899	Aminoacyl-tRNA Synthetase	Cancer
YH16899 binds Lysyl-tRNA synthetase (KRS), and inhibits membrane translocation of KRS. YH16899 impares the interaction of KRS with 67LR. YH16899 inhibits tumor metastasis in mouse models .

HY-167811

*1,2-Dipalmitoyl-sn-glycero-3-[phospho-rac-(3-lysyl(1-glycerol))] hydrochloride* 16:0 lysyl PG hydrochloride	Biochemical Assay Reagents
1,2-Dipalmitoyl-sn-glycero-3-[phospho-rac-(3-lysyl(1-glycerol))] hydrochloride (16:0 Lysyl PG hydrochloride) is a synthetic phospholipid with the activity of promoting the preparation of artificial vesicles.

HY-138625B

PXS-5505 LOX-IN-3 dihydrochloride monohydrate	Monoamine Oxidase	Cardiovascular Disease Cancer
PXS-5505 (LOX-IN-3 dihydrochloride monohydrate) (Compound 33) is an orally active lysyl oxidase (LOX) inhibitor. PXS-5505 can be used for fibrosis, cancer and angiogenesis research .

HY-168569

DDD489	Aminoacyl-tRNA Synthetase	Infection
DDD489 is a potent and selective Cryptosporidium lysyl-tRNA synthetase (CpKRS) inhibitor with IC₅₀ values of 0.85 uM.DDD489 shows anti-cryptosporidials activity in vitro and in vivo .

HY-113770

Lysyl threonine Lys-Thr	Drug Intermediate	Cancer
Lysyl threonine (Lys-Thr) is a dipeptide. Lysyl threonine can be used to synthesize the pentapeptide Gly-Thr-Gly-Lys-Thr. Gly-Thr-Gly-Lys-Thr confers cell sensitivity to anticancer agents by inhibiting the binding of CAGE to GSK3β and reducing the expression of CyclinD1 .

HY-P3750

*Methionyl-Lysyl-Bradykinin* Met-Lys-Bradykinin	Bradykinin Receptor	Cardiovascular Disease Endocrinology
Methionyl-Lysyl-Bradykinin (Met-Lys-Bradykinin), a Bradykinin (HY-P0206) analogue, is a kinin .

HY-120791

Lysyllysine L-lysyl-L-lysine	Drug Intermediate	Others
Lysyllysine (L-Lysyl-L-lysine) is a dipeptide composed of two L-lysine amino acids linked together. Lysyllysine is often used as an enzyme cleavage linker for connecting bioactive peptides, or as a component of more complex antibacterial agents .

HY-W419440

H-Lys-Leu-OH L-Leucine, L-lysyl-	Biochemical Assay Reagents	Others
H-Lys-Leu-OH (L-Leucine, L-lysyl-) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-170573

LOXL2-IN-1	Monoamine Oxidase	Cancer
LOX-IN-5 (compound 22) is a selective and orally active lysyl oxidase-like 2 (LOXL2) inhibitor with an IC₅₀ of <300 nM. LOX-IN-5 possess anti-fibrosis properties .

HY-Y1750R

β-Aminopropionitrile (Standard)	Reference Standards Monoamine Oxidase Endogenous Metabolite	Metabolic Disease Cancer
β-Aminopropionitrile (BAPN) is a specific, irreversible and orally active lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile targets the active site of LOX or LOXL isoenzymes .

HY-149611

Lysyl hydroxylase 2-IN-2	Monoamine Oxidase	Cancer
Lysyl hydroxylase 2-IN-2 (compound 13) is a potent Lysyl hydroxylase 2 (LH2) inhibitor, with the IC₅₀ of approximately 500 nM. Lysyl hydroxylase 2-IN-2 inhibits the migration in 344SQ WT cells, but not impedes the migration of the same cell line with an LH2 knockout cells .

HY-175503

LysRs-IN-4	Bacterial	Infection
LysRS-IN-4 (Compound 49) is an orally active Mycobacterium tuberculosis LysRS (lysyl-tRNA synthetase) inhibitor. LysRS-IN-4 is promising for research of tuberculosis .

HY-175304

DMU371	Parasite	Infection
DMU371 is a Trypanosoma cruzi lysyl-tRNA synthetase 1 (KRS1) inhibitor (IC₅₀=185 nM). DMU371 is promising for research of infectious diseases .

HY-P991156

Rapaprutug	Ras	Inflammation/Immunology
Rapaprutug is a monoclonal antibody targeting human KARS1 (lysyl-tRNA synthetase 1). Rapaprutug blocks the relevant inflammatory signaling pathways in which KARS1 is involved, reducing the production and release of inflammatory factors. Rapaprutug is promising for research of inflammatory diseases .

HY-175305

DMU759	Parasite	Infection
DMU759 is a Lysyl-tRNA synthetase 1 (KRS1) inhibitor. DMU759 has potent anti-kinetoplastid activity against Trypanosoma cruzi , Trypanosoma brucei and Leishmania donovani. DMU759 significantly reduces parasitemia in acute Chagas disease mice model. DMU759 can be used for parasitic infection like Chagas disease research .

HY-107422A

Lenumlostat hydrochloride PAT-1251 hydrochloride; GB2064 hydrochloride	Monoamine Oxidase	Inflammation/Immunology
PAT-1251 Hydrochloride is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC₅₀s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC₅₀s, 0.10, 0.12, and 0.16 μM, respectively). PAT-1251 Hydrochloride is used in the research of fibrotic diseases.

HY-165339

Lysyl-phenylalanyl-lysine	TGF-β Receptor MMP	Others
Lysyl-phenylalanyl-lysine (Compound KFK) is a tripeptide and belongs to the peptide segments related to thrombospondin-1 (TSP-1) (HY-P0299). Lysyl-phenylalanyl-lysine can activate LAP-TGF-β1 and release active TGF-β1, thereby inhibiting abnormal expression of MMP. Lysyl-phenylalanyl-lysine can be used for research on skin aging-related diseases and poor wound healing .

HY-165315

Lysyl-serine TCMP-80	Others	Inflammation/Immunology
Lysyl-serine (TCMP-80) is a T cell modulatory peptide with immunomodulatory properties .

HY-120791A

Lysyllysine trihydrochloride L-lysyl-L-lysine trihydrochloride	Drug Intermediate	Others
Lysyllysine (L-Lysyl-L-lysine) trihydrochloride is a dipeptide composed of two L-lysine amino acids linked together. Lysyllysine trihydrochloride is often used as an enzyme cleavage linker for connecting bioactive peptides, or as a component of more complex antibacterial agents .

HY-128401

Lysidine 2-lysylcytidine	Nucleoside Antimetabolite/Analog Drug Derivative Bacterial	Others
Lysidine (2-lysyl cytidine) is a lysine-containing Cytidine (HY-B0158) derivative. Lysidine can be found at the wobble position of bacterial AUA codon-specific tRNA ^Ile. This modification determines both codon and amino acid specificities of tRNA ^Ile .

HY-D3208

oLOX	Fluorescent Dye	Inflammation/Immunology
oLOX is a fluorescent activity reporter. oLOX can be activated by lysyl oxidase family (LOXF) enzymes, which in turn releases a luciferin fluorescent product that reports LOXF enzyme activity. After oLOX is activated in in vitro fibrotic lung tissues, the fluorescence intensity increases, enabling real-time detection of fibrotic activity. oLOX can be used in studies related to pulmonary fibrosis .

HY-107422R

Lenumlostat (Standard) PAT-1251 (Standard); GB2064 (Standard)	Reference Standards Monoamine Oxidase	Inflammation/Immunology
Lenumlostat (Standard) is the analytical standard of Lenumlostat (HY-107422). This product is intended for research and analytical applications. PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC₅₀s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC₅₀s, 0.10, 0.12, and 0.16 μM, respectively); PAT-1251 is used in the research of fibrotic diseases .

HY-182388

Cinflumide	Others	Inflammation/Immunology
Cinflumide is an orally active muscle relaxant. Cinflumide shows antiinflammatory activity .

HY-180585

LOXL2/sGC modulator-2	Monoamine Oxidase Guanylate Cyclase PKG Collagen	Cardiovascular Disease
LOXL2/sGC modulator-2 (Compound 9k) is a selective and orally active lysyl oxidase-like 2 (LOXL2) and soluble guanylate cyclase (sGC) dual-target regulator. LOXL2/sGC modulator-2 shows inhibitory activity for LOXL2 with an IC₅₀ of 0.1 μM and can activate sGC. LOXL2/sGC modulator-2 can ameliorate vascular remodeling and reduce pulmonary artery pressure. LOXL2/sGC modulator-2 can downregulate PKG1, PCNA, α-SMA, collagen I and fibronectin levels. LOXL2/sGC modulator-2 can be used for the research of pulmonary arterial hypertension .

Cat. No.	Product Name	Target	Research Area

HY-W011165

*L-Lysyl-L-lysine dihydrochloride* lysyllysine dihydrochloride	Peptides	Others
L-Lysyl-L-lysine (Lysyllysine) dihydrochloride is an enzyme cleavable basic amino acid. L-Lysyl-L-lysine dihydrochloride can be used for delivering multiple biologically active peptides .

HY-114788

Lysylcysteine L-lysyl-L-cysteine; Lys-Cys; H-Lys-Cys-OH	Amino Acid Derivatives	Others
Lysylcysteine (L-Lysyl-L-cysteine) is a dipeptide composed of lysine and cysteine.

HY-W010789

*L-Lysyl-L-tyrosine-α-L-lysine* H-Lys-Tyr-Lys-OH; Lys-Tyr-Lys	Amino Acid Derivatives	Others
L-Lysyl-L-tyrosine-α-L-lysine is a lysine derivative .

HY-114788A

Lysylcysteine TFA L-lysyl-L-cysteine TFA; Lys-Cys TFA; H-Lys-Cys-OH TFA	Amino Acid Derivatives	Others
Lysylcysteine (L-Lysyl-L-cysteine) TFA is a dipeptide composed of lysine and cysteine .

HY-113770

Lysyl threonine Lys-Thr	Drug Intermediate	Cancer
Lysyl threonine (Lys-Thr) is a dipeptide. Lysyl threonine can be used to synthesize the pentapeptide Gly-Thr-Gly-Lys-Thr. Gly-Thr-Gly-Lys-Thr confers cell sensitivity to anticancer agents by inhibiting the binding of CAGE to GSK3β and reducing the expression of CyclinD1 .

HY-P3750

*Methionyl-Lysyl-Bradykinin* Met-Lys-Bradykinin	Bradykinin Receptor	Cardiovascular Disease Endocrinology
Methionyl-Lysyl-Bradykinin (Met-Lys-Bradykinin), a Bradykinin (HY-P0206) analogue, is a kinin .

HY-W419440

H-Lys-Leu-OH L-Leucine, L-lysyl-	Biochemical Assay Reagents	Others
H-Lys-Leu-OH (L-Leucine, L-lysyl-) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-120791A

Lysyllysine trihydrochloride L-lysyl-L-lysine trihydrochloride	Drug Intermediate	Others
Lysyllysine (L-Lysyl-L-lysine) trihydrochloride is a dipeptide composed of two L-lysine amino acids linked together. Lysyllysine trihydrochloride is often used as an enzyme cleavage linker for connecting bioactive peptides, or as a component of more complex antibacterial agents .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99047

Simtuzumab AB 0024; GS 6624	Monoamine Oxidase	Cardiovascular Disease Inflammation/Immunology
Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2). Simtuzumab non-competitively blocks collagen cross-linking, reduces LOXL2 protein expression and attenuates extracellular matrix changes. Simtuzumab reduces myocardial fibrosis and prevents cardiac dysfunction. Simtuzumab lowers Myh7 and Nppa gene expression, reduces contraction heterogeneity, and cuts COL1A1 deposition. Simtuzumab can be used for the research of LMNA mutation-induced dilated cardiomyopathy, idiopathic pulmonary fibrosis, and primary sclerosing cholangitis .

HY-P991156

Rapaprutug	Ras	Inflammation/Immunology
Rapaprutug is a monoclonal antibody targeting human KARS1 (lysyl-tRNA synthetase 1). Rapaprutug blocks the relevant inflammatory signaling pathways in which KARS1 is involved, reducing the production and release of inflammatory factors. Rapaprutug is promising for research of inflammatory diseases .

Species:	Human (6) Mouse (2)
Tag:	His (8) MBP (1)
Source:	HEK293 (3) CHO (1) Sf9 insect cells (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71606

	Lysyl oxidase homolog 4 Protein, Mouse (His) Loxl4; Loxc; lysyl oxidase homolog 4; EC 1.4.3.-; lysyl oxidase-like protein 4; lysyl oxidase-related protein C	Mouse	E. coli
	LOXL4 Protein potentially modulates collagenous extracellular matrix formation, suggesting a role in regulating assembly or stability of collagen fibers. Its involvement indicates a contribution to the structural integrity of tissues. The specific mechanisms and contexts of LOXL4 in collagen matrix modulation are areas of interest, emphasizing its potential significance in tissue development and maintenance. Lysyl oxidase homolog 4 Protein, Mouse (His) is the recombinant mouse-derived Lysyl oxidase homolog 4 protein, expressed by E. coli , with N-His labeled tag.

HY-P74771

	LOXL2 Protein, Human (CHO, His) lysyl oxidase homolog 2; lysyl oxidase-related protein WS9-14; LOXL2	Human	CHO
	LOXL2 protein mediates post-translational oxidative deamination of lysine residues, leading to the formation of allysine. It specifically deaminates H3K4me3, inhibits TFIID-dependent transcription, represses E-cadherin, activates the IRE1-XBP1 pathway, and promotes cross-linking of extracellular matrix proteins. LOXL2 is involved in EMT, tumor progression, angiogenesis regulation, and chondrocyte differentiation. LOXL2 Protein, Human (CHO, His) is the recombinant human-derived LOXL2 protein, expressed by CHO , with C-His labeled tag.

HY-P74769

	LOXL2 Protein, Mouse (HEK293, His) lysyl oxidase homolog 2; lysyl oxidase-related protein WS9-14; LOXL2	Mouse	HEK293
	LOXL2 proteins play multifaceted roles in cellular processes by mediating post-translational oxidative deamination of lysine residues, leading to lysine formation. As a transcriptional corepressor, it specifically deaminates histone H3 trimethylated at "Lys-4" (H3K4me3), which is associated with transcriptional activation. LOXL2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived LOXL2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74770

	LOXL2 Protein, Human (HEK293, His) lysyl oxidase homolog 2; lysyl oxidase-related protein WS9-14; LOXL2	Human	HEK293
	LOXL2 protein mediates post-translational oxidative deamination of lysine residues, leading to the formation of allysine. It specifically deaminates H3K4me3, inhibits TFIID-dependent transcription, represses E-cadherin, activates the IRE1-XBP1 pathway, and promotes cross-linking of extracellular matrix proteins. LOXL2 is involved in EMT, tumor progression, angiogenesis regulation, and chondrocyte differentiation. LOXL2 Protein, Human (HEK293, His) is the recombinant human-derived LOXL2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P704257

	LOX Protein, Human (C-His) LOX; Protein-lysine 6-oxidase; lysyl oxidase	Human	E. coli
	LOX proteins play a critical role in the post-translational oxidative deamination of peptidyl lysine residues in collagen and elastin precursors, thereby shaping extracellular matrix dynamics. It regulates Ras expression, suggesting potential tumor suppressive effects, affecting cellular homeostasis and cancer-related processes. LOX Protein, Human (C-His) is the recombinant human-derived LOX protein, expressed by E. coli, with C-6*His labeled tag.

HY-P702915

	LOXL4 Protein, Human (His) LOXC; lysyl oxidase-like 4	Human	E. coli
	LOXL4 Protein, Human (His) is the recombinant human-derived LOXL4, expressed by E. coli , with C-6*His labeled tag. ,

HY-P70840

	KARS Protein, Human (HEK293, His) Lysine--tRNA Ligase; lysyl-tRNA Synthetase; LysRS; KARS; KIAA0070	Human	HEK293
	The KARS protein promotes attachment of amino acids to its cognate tRNA through a two-step reaction, inducing immune responses through monocyte/macrophage activation. In microbial infections, it interacts with the HIV-1 GAG protein to enable selective tRNA(3)(Lys) packaging to initiate reverse transcription. KARS Protein, Human (HEK293, His) is the recombinant human-derived KARS protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P704258

	LOX Protein, Human (sf9, His, MBP) lox; LYOX; LYOX_HUMAN; lysyl oxidase; MGC105112; Protein lysine 6 oxidase; Protein-lysine 6-oxidase	Human	Sf9 insect cells
	LOX proteins play a critical role in the post-translational oxidative deamination of peptidyl lysine residues in collagen and elastin precursors, thereby shaping extracellular matrix dynamics. It regulates Ras expression, suggesting potential tumor suppressive effects, affecting cellular homeostasis and cancer-related processes. LOX Protein, Human (sf9, His, MBP) is the recombinant human-derived LOX protein, expressed by Sf9 insect cells, with C-6*His and N-MBP labeled tag.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Mouse (4) Rabbit (4)
Reactivity:	Human (8) Bovine (1) Rat (4) Mouse (5) Dog (1)
Application:	IHC-P (3) ICC/IF (8) IF-Tissue (1) IP (3) IHC-F (1) WB (8) FC (3)
Isotype:	IgG (4) IgG1 (2)
Conjugation:	Non-conjugated (8)
Clonality:	Monoclonal (6) Recombinant (3)
Modification:	Unmodified (6)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81861

	LOXL2 Antibody (YA1606) LOR2; LOX L2; LOXL2; lysyl oxidase homolog 2; lysyl oxidase like 2; WS9 14	WB, ICC/IF, FC	Human, Mouse, Rat
	LOXL2 Antibody (YA1606) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LOXL2.

HY-P83408

	LOX Antibody (YA3153) lox; LYOX; lysyl oxidase; Protein lysine 6 oxidase	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	LOX Antibody (YA3153) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LOX.

HY-P85266

	KARS Antibody (YA4958) KARS; KIAA0070; Lysine--tRNA ligase; lysyl-tRNA synthetase; LysRS	WB, IHC-P, IHC-F, ICC/IF, IF-Tissue, IP	Human, Mouse
	KARS Antibody (YA4958) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to KARS.

HY-P83408A

	LOX Antibody (YA3153)(PBS only) lox; LYOX; lysyl oxidase; Protein lysine 6 oxidase	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	LOX Antibody (YA3153) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LOX.

HY-P81319

	JMJD6 Antibody (YA1064) JMJD6; KIAA0585; PTDSR; Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; Jumonji domain-containing protein 6; lysyl-hydroxylase JMJD6; Peptide-lysine 5-diox	WB, ICC/IF	Human
	JMJD6 Antibody (YA1064) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to JMJD6.

HY-P85461

	JMJD6 Antibody (YA5153) JMJD6; KIAA0585; PTDSR; Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; Jumonji domain-containing protein 6; lysyl-hydroxylase JMJD6; Peptide-lysine 5-diox	WB, ICC/IF	Human, Mouse, Rat, Bovine, Dog
	JMJD6 Antibody (YA5153) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to JMJD6.

HY-P81319A

	JMJD6 Antibody (YA1064)(PBS only) JMJD6; KIAA0585; PTDSR; Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; Jumonji domain-containing protein 6; lysyl-hydroxylase JMJD6; Peptide-lysine 5-diox	WB, ICC/IF	Human
	JMJD6 Antibody (YA1064) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to JMJD6.

HY-P85485

	JMJD6(N-term) Antibody (YA5177) Apoptotic cell clearance receptor; Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; JMJD 6; JMJD6; JMJD6_HUMAN; Jumonji domain containing 6; Jumonji domain-containing protein 6; KIAA0585; lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor; Protein PTDSR; PSR; PTDSR 1; PTDSR; PTDSR1.	WB, ICC/IF	Human
	JMJD6(N-term) Antibody (YA5177) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to JMJD6(N-term).

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

lysyl

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Antibodies

Oligonucleotides

Natural
Products