Cinflumide
Based on 1 Customer Validation
Cinflumide is an orally active muscle relaxant. Cinflumide shows antiinflammatory activity.
For research use only. We do not sell to patients.
- Purity: 99.78%
- CAS No.: 64379-93-7
- Formula: C12H12FNO
- Molecular Weight:205.23
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | Inhibition |
-13.12 %
Compound: CINFLUMIDE
|
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging
Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging
|
10.21203/rs.3.rs-23951/v1 |
Cinflumide (p.o.) is a potent antiinflammatory agent in rats, with ED50 values of <20 mg/kg for reducing cell accumulation and edema, respectively, in the Carrageenan (HY-125474)-induced pleurisy model[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 64379-93-7
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Appearance Solid
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Molecular Weight 205.23
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Formula C12H12FNO
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Color White to off-white
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SMILES
FC1=CC=CC(/C=C/C(NC2CC2)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (487.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8726 mL | 24.3629 mL | 48.7258 mL | 121.8146 mL |
| 5 mM | 0.9745 mL | 4.8726 mL | 9.7452 mL | 24.3629 mL | |
| 10 mM | 0.4873 mL | 2.4363 mL | 4.8726 mL | 12.1815 mL | |
| 15 mM | 0.3248 mL | 1.6242 mL | 3.2484 mL | 8.1210 mL | |
| 20 mM | 0.2436 mL | 1.2181 mL | 2.4363 mL | 6.0907 mL | |
| 25 mM | 0.1949 mL | 0.9745 mL | 1.9490 mL | 4.8726 mL | |
| 30 mM | 0.1624 mL | 0.8121 mL | 1.6242 mL | 4.0605 mL | |
| 40 mM | 0.1218 mL | 0.6091 mL | 1.2181 mL | 3.0454 mL | |
| 50 mM | 0.0975 mL | 0.4873 mL | 0.9745 mL | 2.4363 mL | |
| 60 mM | 0.0812 mL | 0.4060 mL | 0.8121 mL | 2.0302 mL | |
| 80 mM | 0.0609 mL | 0.3045 mL | 0.6091 mL | 1.5227 mL | |
| 100 mM | 0.0487 mL | 0.2436 mL | 0.4873 mL | 1.2181 mL |