LOXL2-IN-1 tosylate
Based on 1 publication(s) in Google Scholar
LOX-IN-5 tosylate (compound 22) is a selective and orally active lysyl oxidase-like 2 (LOXL2) inhibitor with an IC50 of <300 nM. LOX-IN-5 tosylate possess anti-fibrosis properties.
For research use only. We do not sell to patients.
- Purity: 99.90%
- Formula: C28H33FN4O5S2
- Molecular Weight:588.71
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) LOXL2-IN-1 tosylate
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 588.71
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Formula C28H33FN4O5S2
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Color White to off-white
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SMILES
CC1=CC=C(S(=O)(O)=O)C=C1.NC/C=C(CN2C3=CC=CN=C3C(CC4=CN=C(C=C4)S(C)(=O)=O)=C2C(C)C)\F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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FASEB J
Antibiotic-Loaded Polymethyl Methacrylate Cement Drives Fibroblast-Mediated Angiogenesis via LOXL2 to Accelerate Diabetic Foot Ulcer Healing. [Abstract]2026 Jun 15;40(11):e71881. PMID: 42213591
Solvent & Solubility
DMSO : ≥ 50 mg/mL (84.93 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.6986 mL | 8.4931 mL | 16.9863 mL | 42.4657 mL |
| 5 mM | 0.3397 mL | 1.6986 mL | 3.3973 mL | 8.4931 mL | |
| 10 mM | 0.1699 mL | 0.8493 mL | 1.6986 mL | 4.2466 mL | |
| 15 mM | 0.1132 mL | 0.5662 mL | 1.1324 mL | 2.8310 mL | |
| 20 mM | 0.0849 mL | 0.4247 mL | 0.8493 mL | 2.1233 mL | |
| 25 mM | 0.0679 mL | 0.3397 mL | 0.6795 mL | 1.6986 mL | |
| 30 mM | 0.0566 mL | 0.2831 mL | 0.5662 mL | 1.4155 mL | |
| 40 mM | 0.0425 mL | 0.2123 mL | 0.4247 mL | 1.0616 mL | |
| 50 mM | 0.0340 mL | 0.1699 mL | 0.3397 mL | 0.8493 mL | |
| 60 mM | 0.0283 mL | 0.1416 mL | 0.2831 mL | 0.7078 mL | |
| 80 mM | 0.0212 mL | 0.1062 mL | 0.2123 mL | 0.5308 mL |
LOXL2-IN-1 tosylate Related Classifications
HY-170573A Related Classifications
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