LOX Antibody (YA3153)(PBS only)

Cat. No.: HY-P83408A: Data Sheet User Guide for Antibodies
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LOX Antibody (YA3153) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LOX.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

LOX Antibody (YA3153) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LOX.

Host

Rabbit

Molecular Weight

Predicted band size: 47 kDa;

Observed band size: 50 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P28300

Gene ID

4015 [NCBI]

Immunogen

A synthesized peptide derived from human LOX

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
IP IP: Immunoprecipitation	1:50
FC FC: Flow Cytometry	1:50-1:100

Purity	Affinity Chromatography	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin (PubMed:26838787). Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity)

Subcellular Localization：Secreted; Secreted, extracellular space

Expression：
Tissue_specificity:Heart, placenta, skeletal muscle, kidney, lung and pancreas

Subunit：Interacts with MFAP4 (PubMed:26601954). Interacts (via propeptide) with EFEMP2; this interaction is strong and facilitates formation of ternary complexes with ELN during elastic fiber assembly; this interaction limits interaction of EFEMP2 with FBLN5 (PubMed:19855011)

Research Field

Signal Transduction

Synonyms

lox; LYOX; Lysyl oxidase; Protein lysine 6 oxidase

Documentation

User Guide for Antibodies (1077 KB)