40 Results for "

vitamin A deficiency

" in MedChemExpress (MCE) Product Catalog:
Products (40)

40 Results for "vitamin A deficiency" in MCE Product Catalog:

29
29 Publications Verification
Cat. No.: HY-16637
CAS No.: 59-30-3
Synonyms: vitamin B9; vitamin M
Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .
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29
29 Publications Verification
Cat. No.: HY-16637D
CAS No.: 29704-76-5
Synonyms: vitamin B9 disodium; vitamin M disodium
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 5 g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .
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5
5 Cited Publications
Cat. No.: HY-137808
CAS No.: 108347-97-3
Purity:  94%
Synonyms: Succinyl-CoA sodium
Succinyl CoA (Succinyl-coenzyme A) sodium is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA sodium is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA sodium acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA sodium insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA sodium can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .
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4
4 Cited Publications
Cat. No.: HY-103395
CAS No.: 516-05-2
Purity:  ≥98.0%
Synonyms: Methylpropanedioic acid; Methylmalonate
Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.
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3
3 Cited Publications
Cat. No.: HY-B2209A
CAS No.: 59461-30-2
Synonyms: vitamin B12a monohydrochloride
Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .
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3
3 Cited Publications
Cat. No.: HY-B2209
CAS No.: 13422-51-0
Synonyms: vitamin B12a
Hydroxocobalamin (Vitamin B12a) is a cyanide antidote. Hydroxocobalamin can decrease the cell and plasma cyanide concentrations and increase survival rate in acute cyanide poisoning. Hydroxocobalamin can improve newborn Cbl-C defect-induced metabolic profile and neurocognitive outcome. Hydroxocobalamin can normalize Vitamin B12 deficiency. Hydroxocobalamin can induce acute kidney injury. Hydroxocobalamin can be used for the researches of metabolic and neurological disease .
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3
3 Cited Publications
Cat. No.: HY-B2209B
CAS No.: 22465-48-1
Synonyms: vitamin B12a acetate
Hydroxocobalamin acetate is an injectable natural vitamin B12. Hydroxocobalamin acetate binds to NO. Hydroxocobalamin acetate detoxifies Cyanide and NaSH. Hydroxocobalamin acetate reduces hypotension. Hydroxocobalamin acetate is used in research related to vitamin B12 deficiency, including pernicious anemia .
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1
1 Cited Publications
Cat. No.: HY-B0921
CAS No.: 116-43-8
Synonyms: Succinylsulphathiazole
Succinylsulfathiazole (Succinylsulphathiazole) is a long-acting sulfonamide antibiotic with localized gut-specific antibacterial activity and is orally active. Succinylsulfathiazole inhibits bacterial folate synthesis, reduces coliform counts, suppresses intestinal bacterial growth and vitamin biosynthesis, and depletes gut folate-producing bacteria. Succinylsulfathiazole modulates hepatic mTOR signaling, diminishes cecal fermentation, decreases hepatic folate levels and total folate excretion, elevates nitrogen excretion and reduces the fermentability of certain dietary fibers. Succinylsulfathiazole induces folate deficiency and triggers biotin- and folate-related nutritional deficiency symptoms in rats and C57BL/6 mice .
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1
1 Cited Publications
Cat. No.: HY-16637R
CAS No.: 59-30-3
Synonyms: vitamin B9 (Standard); vitamin M (Standard)
Folic acid (Standard) is the analytical standard of Folic acid. This product is intended for research and analytical applications. Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .
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Cat. No.: HY-B2082
CAS No.: 804-30-8
Fursultiamine is a vitamin B1 derivative, has anti-nociceptive and antineoplastic activity. Fursultiamine can be used for vitamin B1?deficiency, osteoarthritis (OA) and cancer research .
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Cat. No.: HY-113092
CAS No.: 17298-37-2
Purity:  ≥98.0%
Propionylcarnitine is metabolized by carnitine acetyltransferase from propionyl-CoA. Increased propionylcarnitine is regarded as a biomarker of vitamin B12 deficiency .
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Cat. No.: HY-W017464
CAS No.: 50700-49-7
Synonyms: N-Acetyl-4-benzoquinone Imine
NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver .
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Cat. No.: HY-116073
CAS No.: 1113-41-3
Target:  

Acyltransferase

Research Areas:  

Infection Cancer

L-Penicillamine is an orally active serine palmitoyltransferase (SPT) inhibitor. L-Penicillamine inactivates the PLP cofactor by forming adducts, thereby inhibiting SPT activity and reducing sphingolipid biosynthesis. L-Penicillamine not only blocks tumor access to vitamin B6, but also stabilizes the human papillomavirus 16 E6 oncoprotein monomer and inhibits its polymerization, exhibiting a unique anticancer mechanism. L-Penicillamine effectively delays the growth of Sarcoma-180, induces tumor necrosis and prolongs survival (though long-term use may lead to Pyridoxine (HY-B1328) deficiency and weight loss) .
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Cat. No.: HY-E70544B
CAS No.: 9001-29-0
Canine Factor X is a vitamin K-dependent plasma serine protease that is activated to generate Factor Xa. Canine Factor X mediates the common coagulation pathway and catalyzes the conversion of prothrombin to thrombin . Canine Factor X is the first enzyme to act in the common pathway of thrombosis in the coagulation cascade. Canine Factor X can be used in studies related to Factor X deficiency .
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Cat. No.: HY-139410
CAS No.: 9005-46-3
Sodium caseinates is a kind of sodium salts of major milk proteins, which act as protein-based biopolymers and innate immune system activators. Sodium caseinates induce granulopoiesis, activation and differentiation, promote the production of M-CSF, and increase serum levels of G-CSF and GM-CSF. Sodium caseinates inhibit the proliferation and reduce the viability of leukemia macrophage-like cells, thereby significantly improving the survival rate of mice inoculated with leukemia cells. Sodium caseinates can serve as carriers for probiotics in edible films and exhibit anti-Listeria activity. Sodium caseinates effectively protect vitamin A from degradation, enhance its stability, bioaccessibility and bioavailability, and regulate protein digestibility when complexed with vitamin A. Sodium caseinates can be applied to research related to acute monocytic leukemia and vitamin A deficiency .
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Cat. No.: HY-103395S1
CAS No.: 1173019-21-0
Methylmalonic acid- 13C4 is the 13C labeled Methylmalonic acid . Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer .
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Cat. No.: HY-148285
CAS No.: 604-98-8
Synonyms: Succinyl-coenzyme A; S-(Hydrogen succinyl)coenzyme A
Succinyl CoA (Succinyl-coenzyme A) is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .
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Cat. No.: HY-103395R
CAS No.: 516-05-2
Synonyms: Methylpropanedioic acid (Standard); Methylmalonate (Standard)
Methylmalonic acid (Standard) is the analytical standard of Methylmalonic acid. This product is intended for research and analytical applications. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.
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Cat. No.: HY-103395S
CAS No.: 42522-59-8
Purity:  98.91%
Synonyms: Methylpropanedioic acid-d3; Methylmalonate-d3
Methylmalonic acid-d3 is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer .
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Cat. No.: HY-16637A
CAS No.: 6484-89-5
Synonyms: vitamin B9 sodium; vitamin M sodium
Folic acid (Vitamin B9) sodium is a orally active essential nutrient from the B complex group of vitamins. Folic acid sodium shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid sodium can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .
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