1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite

Methylmalonate (Synonyms: Isosuccinic acid; Methylmalonic acid; Methylpropanedioic acid)

Cat. No.: HY-103395 Purity: >97.0%
Handling Instructions

Methylmalonate is an indicator of Vitamin B-12 deficiency in cancer.

For research use only. We do not sell to patients.

Methylmalonate Chemical Structure

Methylmalonate Chemical Structure

CAS No. : 516-05-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
1 g USD 50 In-stock
Estimated Time of Arrival: December 31
5 g   Get quote  
10 g   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Methylmalonate is an indicator of Vitamin B-12 deficiency in cancer.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Vitamin B-12 is required for Methylmalonate (Methylmalonic acid; MMA) to be converted to succinyl-CoA, and in combination with folic acid, for homocysteine (HC) to be converted to methionine. Therefore, Methylmalonate is clearly more specific to vitamin B-12 deficiency compared to HC[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.4681 mL 42.3406 mL 84.6812 mL
5 mM 1.6936 mL 8.4681 mL 16.9362 mL
10 mM 0.8468 mL 4.2341 mL 8.4681 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

118.09

Formula

C₄H₆O₄

CAS No.

516-05-2

SMILES

O=C(O)C(C)C(O)=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: >97.0%

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Methylmalonate
Cat. No.:
HY-103395
Quantity:

Methylmalonate

Cat. No.: HY-103395