516-05-2
516-05-2
Chemical Structure
Methylmalonic acid
Synonym(s): Methylpropanedioic acid; Methylmalonate
- CAS No.: 516-05-2
- Formula:C4H6O4
- Molecular Weight:118.09
IUPAC Name: 2-methylmalonic acid
InChIKey: ZIYVHBGGAOATLY-UHFFFAOYSA-N
SMILES: O=C(O)C(C)C(O)=O
Biological Activity: Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Methylmalonic acid | 98.0% | Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer. | ||||||||||||||||||||
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Methylmalonic acid (Standard) | 99.19% | Methylmalonic acid (Standard) is the analytical standard of Methylmalonic acid. This product is intended for research and analytical applications. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer. | ||||||||||||||||||||
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Methylmalonic acid-d3 | 98.91% | Methylmalonic acid-d3 is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer. | ||||||||||||||||||||
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Methylmalonic acid-13C4 | 99.6% | Methylmalonic acid-13C4 is the 13C labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer. | ||||||||||||||||||||
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Aminomalonic acid | 99.97% | Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis. | ||||||||||||||||||||
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3-Methylglutaric acid | 98.0% | 3-Methylglutaric acid is a non-selective inhibitor of mitochondrial function and Na+, K+-ATPase, with an inhibition rate of 30% on rat cortical synaptosomal Na+, K+-ATPase. 3-Methylglutaric acid can induce reactive oxygen species (ROS) generation, thereby causing oxidative damage and inhibiting mitochondrial redox potential and ion pump function of cell membranes. 3-Methylglutaric acid can be used to study the neuropathological mechanisms of metabolic diseases and the role of oxidative stress-mediated neuronal damage in neurodegeneration. | ||||||||||||||||||||
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Ethylmalonic acid | 98.0% | Ethylmalonic acid is a short-chain organic dicarboxylic acid. Ethylmalonic acid synergistically induces mitochondrial permeability transition (MP) with Ca2+, inhibits Mi-CK, and disrupts mitochondrial energy metabolism. Ethylmalonic acid can be used in the research of SCADD, EE and other genetic metabolic diseases characterized by EMA accumulation. | ||||||||||||||||||||
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Ethylmalonic acid (Standard) | ≥98% | Ethylmalonic acid (Standard) is the analytical standard of Ethylmalonic acid (HY-34740). This product is intended for research and analytical applications. Ethylmalonic acid is a short-chain organic dicarboxylic acid. Ethylmalonic acid synergistically induces mitochondrial permeability transition (MP) with Ca2+, inhibits Mi-CK, and disrupts mitochondrial energy metabolism. Ethylmalonic acid can be used in the research of SCADD, EE and other genetic metabolic diseases characterized by EMA accumulation. | ||||||||||||||||||||
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Ethylmalonic acid-d3 | 98.0% | Ethylmalonic acid-d3 is the deuterium labeled Ethylmalonic acid (HY-34740). Ethylmalonic acid is a short-chain organic dicarboxylic acid. Ethylmalonic acid synergistically induces mitochondrial permeability transition (MP) with Ca2+, inhibits Mi-CK, and disrupts mitochondrial energy metabolism. Ethylmalonic acid can be used in the research of SCADD, EE and other genetic metabolic diseases characterized by EMA accumulation. | ||||||||||||||||||||
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Ethylmalonic acid-d5 | Ethylmalonic acid-d5 is the deuterium labeled Ethylmalonic acid (HY-34740). Ethylmalonic acid is a short-chain organic dicarboxylic acid. Ethylmalonic acid synergistically induces mitochondrial permeability transition (MP) with Ca2+, inhibits Mi-CK, and disrupts mitochondrial energy metabolism. Ethylmalonic acid can be used in the research of SCADD, EE and other genetic metabolic diseases characterized by EMA accumulation. | |||||||||||||||||||||
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D-Alanine-d3 | 99.83% | D-Alanine-d3 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR. | ||||||||||||||||||||
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L-Alanine-d3 | 99.92% | L-Alanine-d3 is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system. | ||||||||||||||||||||
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3-Hydroxy-2-methylglutaric acid | 3-Hydroxy-2-methylglutaric acid is a carboxylic acid metabolite. 3-Hydroxy-2-methylglutaric acid can be isolated from the flower Veronica incana L. 3-Hydroxy-2-methylglutaric acid can be used for upper respiratory tract diseases, malignant neoplasms, gastrointestinal tract and genitourinary system disorders and diabetes mellitus research. | |||||||||||||||||||||
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DL-Alanine-d3 | 98.0% | DL-Alanine-d3 is the deuterium labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver. | ||||||||||||||||||||
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2-Methylsuccinic acid | 98.0% | 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy. | ||||||||||||||||||||
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2-Methylsuccinic acid (Standard) | 99.90% | 2-Methylsuccinic acid (Standard) is the analytical standard of 2-Methylsuccinic acid. This product is intended for research and analytical applications. 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy. | ||||||||||||||||||||
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Tartronic acid | 98.0% | Tartronic acid, a dicarboxylic acid derive, is an inhibitor of the transformation of carbohydrates into fat under fat-deficient diet conditions. Tartronic acid promotes 3T3-L1 adipocyte differentiation by increasing the protein expression of FABP-4, PPARγ and SREBP-1. Tartronic acid promotes de novo lipogenesis and inhibits CPT-1β by upregulating acetyl-CoA and malonyl-CoA. Tartronic acid promotes weight gain and induces adipocyte hypertrophy in epididymal white adipose tissue and lipid accumulation in the livers of high-fat diet induced obese mice. Tartronic acid can be used for lipid metabolic disease research. | ||||||||||||||||||||
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2-Methylpentanedioic acid | 98.0% | 2-Methylpentanedioic acid is a metabolite of succinic acid, a citric acid cycle intermediate. | ||||||||||||||||||||
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2-Methylpentanedioic acid (Standard) | ≥98% | 2-Methylpentanedioic acid (Standard) is the analytical standard of 2-Methylpentanedioic acid. This product is intended for research and analytical applications. 2-Methylpentanedioic acid is a metabolite of succinic acid, a citric acid cycle intermediate. | ||||||||||||||||||||
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(R)-3-Amino-2-methylpropanoic acid-d3 | (R)-3-Amino-2-methylpropanoic acid-d3 is the deuterium labeled (R)-3-Amino-2-methylpropanoic acid. | |||||||||||||||||||||
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(R)-2-Methylbutanoic acid-d3 | (R)-2-Methylbutanoic acid-d3 is the deuterium labeled (R)-2-Methylbutanoic acid. | |||||||||||||||||||||
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3-Aminoisobutyric acid-d3 hydrochloride | 3-Aminoisobutyric acid-d3 hydrochloride is the deuterium labeled 3-Aminoisobutyric acid hydrochloride. | |||||||||||||||||||||
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(S)-2-(Methyl-d3)butanoic acid | (S)-2-(Methyl-d3)butanoic acid is the deuterium labeled (S)-2-Methylbutanoic acid (HY-W077891). | |||||||||||||||||||||
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(2R,3S)-3-Methylmalic acid | (2R,3S)-3-Methylmalic acid (compound 4b) is a synthon for 2-methyl-3-hydroxy-butyrolactones. | |||||||||||||||||||||
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