Search Result

Results for "

carboxymethyl-

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Amino Acid Derivatives (1) Antibiotic (1) Apoptosis (3) Autophagy (3) Bacterial (4) Bcl-2 Family (3) Biochemical Assay Reagents (44) Caspase (1) CD38 (1) Cholecystokinin Receptor (1) CRFR (2) Drug Derivative (3) Drug Metabolite (2) Endogenous Metabolite (2) Environmental Pollutants (7) ERK (1) Ferroportin (1) Fluorescent Dye (2) GLP Receptor (2) HCV (2) Insulin Receptor (2) Isotope-Labeled Compounds (6) Melanocortin Receptor (1) MMP (1) MOFs (5) NF-κB (1) Nucleoside Antimetabolite/Analog (1) p38 MAPK (2) Phosphatase (1) Polo-like Kinase (PLK) (1) PROTAC Linkers (3) Reactive Oxygen Species (ROS) (3) Reference Standards (4) Taste Receptor (2) Vasopressin Receptor (1) Virus Protease (1) α-synuclein (2)
By Research Areas:	Cancer (10) Cardiovascular Disease (1) Infection (10) Inflammation/Immunology (4) Metabolic Disease (8) Neurological Disease (6)
Oligonucleotides:	Nucleoside Analogs (1) Suspending Agents (1) Disintegrants (2) Uridine (1) Binders (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0703

*Sodium carboxymethyl* cellulose (Viscosity:800-1200 mPa.s)** 45+ Cited Publications CMC-Na (Viscosity:800-1200 mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Sodium carboxymethyl cellulose (Viscosity:800-1200 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

HY-Y1889A

*Sodium carboxymethyl* cellulose (MW 250000)** 5+ Cited Publications CMC-Na (MW 250000); CMC-Na (Viscosity:1500-3100 mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Sodium carboxymethyl cellulose (CMC-Na) (MW 250000) is a sodium salt of carboxymethyl cellulose. Sodium carboxymethyl cellulose has adsorption and corrosion inhibition on low-carbon steel in an acidic medium. Sodium carboxymethyl cellulose can be used as a thickener, paste and barrier agent .

HY-W250111

Carboxymethyl chitosan	Biochemical Assay Reagents Apoptosis Reactive Oxygen Species (ROS) Bcl-2 Family Caspase	Cancer
Carboxymethyl chitosan is a derivative of chitosan. Carboxymethyl chitosan inhibits Apoptosis and ROS. Carboxymethyl chitosan increases the expression of Bcl-2 and reduces the expression of Bax, cytochrome c and caspase-3. Carboxymethyl chitosan inhibits the migration of various cells. Carboxymethyl chitosan exerts antitumor effects on Lewis tumors and hepatocarcinoma .

HY-134124

*Glutathione ethyl* ester**	Reactive Oxygen Species (ROS)	Metabolic Disease
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-Y0703C

*Sodium carboxymethyl* cellulose (Viscosity:300-800mpa.s)** CMC-Na (Viscosity:300-800mpa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Sodium carboxymethyl cellulose (Viscosity:300-800mpa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

HY-W286743

*Nε-(Carboxymethyl)-L-lysine* 1 Publications Verification CML; N6-(carboxymethyl)-L-lysine; Nε-(1-carboxymethyl)-L-lysine	Polo-like Kinase (PLK) ERK NF-κB	Cancer
Nε-(Carboxymethyl)-L-lysine (CML) is an orally active advanced glycation end product. Nε-(Carboxymethyl)-L-lysine upregulates the expression of PLK1 and CEP20, and induces the activation of RAGE and ERK/NFκB. Nε-(Carboxymethyl)-L-lysine drives centrosome amplification. Nε-(Carboxymethyl)-L-lysine induces malignant transformation of hepatocytes and promotes the development of hepatocellular carcinoma. Nε-(Carboxymethyl)-L-lysine induces epithelial-mesenchymal transition in osteosarcoma cells and enhances their migration and invasion properties .

HY-Y0703A

*Sodium carboxymethyl* cellulose (Viscosity:1200-1400 mPa.s)** CMC-Na (Viscosity:1200-1400 mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Sodium carboxymethyl cellulose (Viscosity:1200-1400 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

HY-Y1889

*Sodium carboxymethyl* cellulose (Viscosity:5000-15000 mPa.s)** CMC-Na (Viscosity:5000-15000 mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

HY-Y0703D

*Sodium carboxymethyl* cellulose (average Mw 90000)** CMC-Na (average Mw 90000, DS=0.7, Viscosity:50-200 mPa.s)	Environmental Pollutants Biochemical Assay Reagents	Others
Sodium carboxymethyl cellulose (average Mw 90000, DS=0.7, Viscosity:50-200 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent .

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-100047

*Nα,Nα-Bis(carboxymethyl)-L-lysine*	Taste Receptor	Others
Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC₅₀ of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study .

HY-B2221C

CM Cellulose CM-32 carboxymethyl cellulose CM-32; CM-32	Environmental Pollutants Biochemical Assay Reagents	Others
CM Cellulose CM-32 (Carboxymethyl cellulose) is a cellulose derivative. CM Cellulose CM-32 has a wide range of applications in the biomedical field, including tissue engineering, wound dressing, absorbent nonwovens, fabrication of 3D-scaffolds for biocompatible implants, artificial organs or mimics of extracellular polymeric matrix and diagnosis of various diseases. CM Cellulose CM-32 can decrease osteoclasts formation. CM Cellulose CM-32 can be used as a biological material or organic compound for life science related research .

HY-W004761

Tetrahydroxydiboron Hypodiboric acid	Biochemical Assay Reagents Reactive Oxygen Species (ROS)	Infection
Tetrahydroxydiboron acts as a hydrogel initiator and bioadhesion promoter, with broad-spectrum antibacterial activity, ROS scavenging capacity and osteogenic induction properties. Tetrahydroxydiboron initiates rapid gelation by generating free radicals through reactions with vinyl monomers and dissolved oxygen, and overcomes oxygen inhibition without deoxygenation or external triggers. Tetrahydroxydiboron achieves strong bioadhesion through interaction with carboxymethyl chitosan. Tetrahydroxydiboron can be used in the research of periodontitis and related inflammatory diseases .

HY-P1108A

Astressin 2B TFA 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .

HY-P1108

Astressin 2B 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .

HY-D0980

Biotin-DADOO Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin	Biochemical Assay Reagents	Infection
Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin) is a biotin-containing amine compound and a biotinylation reagent. As an amino component, Biotin-DADOO participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. Biotin-DADOO can be conjugated with carboxymethyl cellulose derivatives. Biotin-DADOO is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A .

HY-114118S1

Semaglutide-d8 tetraTFA	Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family	Neurological Disease Metabolic Disease Cancer
Semaglutide-d₈ tetraTFA is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .

HY-114118S

Semaglutide-d8	Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family	Neurological Disease Metabolic Disease Cancer
Semaglutide-d₈ is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .

HY-P2336A

CCZ01048 TFA 3 Publications Verification	Melanocortin Receptor	Cancer
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .

HY-126393

Carboxymethyl-β-cyclodextrin	Biochemical Assay Reagents	Others
Carboxymethyl-β-cyclodextrin is a cationic cyclodextrin used as a carrier for drugs. It has been shown to bind nonsteroidal anti-inflammatory drugs (NSAIDs) with high affinity and selectivity.

HY-75005

*1-Boc-4-carboxymethyl* piperazine**	PROTAC Linkers	Cancer
1-Boc-4-carboxymethyl piperazine is a PROTAC linker. 1-Boc-4-carboxymethyl piperazine can be used in the synthesis of PROTACs (e.g. PROTAC IRAK4 degrader-12 (HY-168586)) .

HY-164071

Carboxymethyl Dextran CM-Dextran	Drug Derivative	Others
Carboxymethyl Dextran (CM-Dextran) is a dextran derivative and a biocompatible coating for superparamagnetic iron oxide nanoparticles. When coated on the surface of superparamagnetic nanoparticles, Carboxymethyl Dextran forms stable particles across all pH values and NaCl concentrations. Carboxymethyl Dextran can be used to prepare materials for magnetic resonance molecular imaging .

HY-Y0703E

*Sodium carboxymethyl* cellulose (Viscosity:2500-6000mpa.s)**	Biochemical Assay Reagents	Others
Sodium carboxymethyl cellulose (Viscosity:2500-6000mpa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent .

HY-P10143

MMP-2/MMP-9 Substrate Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt	MMP	Others
MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .

HY-W1048555A

Mal-PEG2000-SCM	Biochemical Assay Reagents	Others
Mal-PEG2000-SCM is a heterobifunctional PEG crosslinker bearing maleimide and succinimidyl carboxymethyl ester functional groups. MMal-PEG2000-SCM conjugates the F3 peptide to nanoparticles: the SCM group reacts with amino groups on the nanoparticle surface to form amide groups, while the MAL group reacts with thiol groups of the F3 peptide to form carbon-sulfur bonds. Mal-PEG-SCM enables unidirectional addition of linkers, ensuring that appropriate functional groups are available for RGD incorporation. Mal-PEG2000-SCM can be used in the development of nanoparticles targeting specific tumor cells .

HY-A0248AS

Polymyxin B1-d7 TFA	Isotope-Labeled Compounds Bacterial	Infection
Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-158223

Carboxymethyl chitosan Methacryloyl CMCSMA	Biochemical Assay Reagents	Others
Carboxymethyl chitosan Methacryloyl (CMCSMA) is methacrylated carboxymethyl chitosan with properties as a 3D printing ink. A composite hydrogel made of Carboxymethyl chitosan Methacryloyl can effectively accelerate bone healing in an infectious microenvironment after implantation in a rat model of Staphylococcus aureus-infected femoral defect . Carboxymethyl chitosan Methacryloyl needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.

HY-W000969

*4-(Carboxymethyl)phenylboronic acid pinacol ester*	PROTAC Linkers	Cancer
4-(Carboxymethyl)phenylboronic acid pinacol ester is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-162836

Rifamycin B 4-O-(carboxymethyl)-Rifamycin	Antibiotic Bacterial	Infection
Rifamycin B (4-O-(Carboxymethyl)-Rifamycin) is a member of ansamycin antibiotics family with an anti-mycobacterial activity against tuberculosis, leprosy and AIDS-related mycobacterial infections. Rifamycin B is a metabolic product of Nocardia inediterranei, which can yield Rifamycin O and Rifamycin S (HY-125365) by microbial transformation .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-W016194

*1-(Carboxymethyl)cyclohexanecarboxylic acid* 1-Carboxycyclohexaneacetic acid; Gabapentin Impurity E; Gabapentin Related Compound E	5-HT Receptor	Neurological Disease
1-(Carboxymethyl)cyclohexanecarboxylic acid (1-Carboxycyclohexaneacetic acid; Gabapentin Impurity E) is a potential impurity in commercial preparations of the antiepileptic agent Gabapentin (HY-A0057). It is also used as a precursor for the synthesis of a serotonin (5-HT) receptor subtype 5-HT2A antagonist.

HY-B2220B

Thermostable cellulase (recombinant)	Endogenous Metabolite	Others
Thermostable cellulase recombinant is a cellulose hydrolase present in hyperthermophiles, which catalyzes the hydrolysis of β-1,4 glycosidic bonds in cellulose. Thermostable cellulase recombinant targets carboxymethyl cellulose (CMC) as its primary substrate, and retains high residual activity even after incubation at high temperatures. The activity of Thermostable cellulase recombinant is inhibited by ionic and non-ionic detergents, and can be enhanced by cobalt ions. Thermostable cellulase recombinant can be applied in the paper industry .

HY-W1113135

Carboxymethyl-β-cyclodextrin sodium salt	Biochemical Assay Reagents	Others
Carboxymethyl-β-cyclodextrin sodium salt is a negatively charged β-cyclodextrin derivative, as well as a metal ion chelator and solubilizing reagent. Carboxymethyl-β-cyclodextrin sodium salt forms stable aqueous complexes with Ba ²⁺, Ca ²⁺, Cd ²⁺, Ni ²⁺, Pb ²⁺, Sr ²⁺, and Zn ²⁺ ions. Carboxymethyl-β-cyclodextrin sodium salt derived hydrogel carriers support oral insulin delivery via paracellular permeation across Caco-2 monolayers and produce sustained hypoglycemic effects in diabetic mice. Carboxymethyl-β-cyclodextrin sodium salt can be conjugated onto folate-modified BSA nanoparticles to boost folate receptor-mediated endocytosis, elevate intracellular anticancer drug uptake and trigger cell apoptosis. Carboxymethyl-β-cyclodextrin sodium salt can be utilized for chiral separation in capillary electrophoresis, development of nanoscale drug carriers and nucleic acid transfection research .

HY-W127837

2-Aminooxyethyliminodiacetic acid hydrochloride N-[2-(AMinooxy)ethyl]-N-(carboxymethyl)glycine hydrochloride	Biochemical Assay Reagents	Others
2-Aminooxyethyliminodiacetic Acid Hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P3066

SKF 100398 d(CH2)5Tyr(Et)VAVP	Vasopressin Receptor	Metabolic Disease
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .

HY-W009913

*2-((Carboxymethyl)amino)benzoic acid*	Amino Acid Derivatives	Others
2-((Carboxymethyl)amino)benzoic acid is a Glycine (HY-Y0966) derivative .

HY-154704

*Calcium carboxymethyl* cellulose**	Biochemical Assay Reagents	Others
Calcium carboxymethyl cellulose can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-W554021

*S-Carboxymethyl-L-cysteine L-lysine monohydrate* Carbocisteine lysine; Carbocysteine-L-lysine	Others	Inflammation/Immunology
S-Carboxymethyl-L-cysteine L-lysine monohydrate (Carbocisteine lysine) is a mucosal active drug with anti-inflammatory and antioxidant activities, which can be used in the research of chronic obstructive pulmonary disease (COPD) .

HY-W286743S1

CML-d3 N6-(carboxymethyl)-L-lysine-d₃; Nε-(1-carboxymethyl)-L-lysine-d₃	Isotope-Labeled Compounds	Others
CML-d₃ is the deuterium labeled CML.

HY-P10828

MAPI	Virus Protease	Infection Inflammation/Immunology
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .

HY-W1048555B

Mal-PEG3400-SCM	Biochemical Assay Reagents	Others
Mal-PEG3400-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG3400-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .

HY-140723

**Carboxymethyl-PEG5000-Carboxymethyl**	PROTAC Linkers	Cancer
Carboxymethyl-PEG5000-Carboxymethyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-CE00532

*2-Carboxymethyl-3-hydroxyphenylpropionyl-CoA* 2-carboxymethyl-3-hydroxyphenylpropionyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
2-Carboxymethyl-3-hydroxyphenylpropionyl-CoA (2-Carboxymethyl-3-hydroxyphenylpropionyl-coenzyme A) is an acyl-CoA.

HY-160764

*N6-Carboxymethyl-ATP*	Drug Derivative	Others
N6-Carboxymethyl-ATP is the alkylation product of ATP with iodoacetic acid at pH 6.5, where alkylation of ATP with iodoacetic acid at pH 6.5 yielded 1-carboxymethyl-ATP which, after alkaline rearrangement gave N6-carboxymethyl-ATP .

HY-152465

*5-Carboxymethyl-2-thiouridine*	Nucleoside Antimetabolite/Analog	Cancer
5-Carboxymethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-D0205

(RS)-Carbocisteine S-(carboxymethyl)-DL-cysteine	Biochemical Assay Reagents	Others
(RS)-Carbocisteine is the S-carboxymethyl cysteine with no detectable inhibitory effect. (RS)-Carbocisteine is the inactive enantiomer of Carbocisteine.

HY-133246A

*Monodes(N-carboxymethyl)valine Daclatasvir TFA* Daclatasvir Impurity A TFA	HCV	Infection
Monodes(N-carboxymethyl)valine Daclatasvir TFA (Daclatasvir Impurity A TFA) is the TFA salt form of Monodes(N-carboxymethyl)valine Daclatasvir (HY-133246). Monodes(N-carboxymethyl)valine Daclatasvir TFA is the main degradation product of Daclatasvir (HY-10466). Daclatasvir is a potent HCV NS5A protein inhibitor .

HY-W587411S

*Mono[2-(carboxymethyl)hexyl] phthalate-d4*	Isotope-Labeled Compounds	Others
Mono[2-(carboxymethyl)hexyl] phthalate-d₄ is a deuterium labeled compound.

HY-W093254A

*Poly(ethylene glycol) bis(carboxymethyl) ether (MW 250)*	Biochemical Assay Reagents	Others
Poly(ethylene glycol) bis(carboxymethyl) ether (MW 250) is an amine-reactive crosslinking agent .

Cat. No.	Product Name	Type

HY-D0089

O'-(carboxymethyl)fluoresceinamide

Fluorescent Dye

O'-(carboxymethyl)fluoresceinamide is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

Cat. No.	Product Name	Type

HY-Y0703

*Sodium carboxymethyl* cellulose (Viscosity:800-1200 mPa.s)** 45+ Cited Publications CMC-Na (Viscosity:800-1200 mPa.s)	Biochemical Assay Reagents
Sodium carboxymethyl cellulose (Viscosity:800-1200 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

HY-Y1889A

*Sodium carboxymethyl* cellulose (MW 250000)** 5+ Cited Publications CMC-Na (MW 250000); CMC-Na (Viscosity:1500-3100 mPa.s)	Biochemical Assay Reagents
Sodium carboxymethyl cellulose (CMC-Na) (MW 250000) is a sodium salt of carboxymethyl cellulose. Sodium carboxymethyl cellulose has adsorption and corrosion inhibition on low-carbon steel in an acidic medium. Sodium carboxymethyl cellulose can be used as a thickener, paste and barrier agent .

HY-W250111

Carboxymethyl chitosan

Biochemical Assay Reagents

Carboxymethyl chitosan is a derivative of chitosan. Carboxymethyl chitosan inhibits Apoptosis and ROS. Carboxymethyl chitosan increases the expression of Bcl-2 and reduces the expression of Bax, cytochrome c and caspase-3. Carboxymethyl chitosan inhibits the migration of various cells. Carboxymethyl chitosan exerts antitumor effects on Lewis tumors and hepatocarcinoma .

HY-Y0703C

*Sodium carboxymethyl* cellulose (Viscosity:300-800mpa.s)** CMC-Na (Viscosity:300-800mpa.s)	Biochemical Assay Reagents
Sodium carboxymethyl cellulose (Viscosity:300-800mpa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

HY-W286743

Nε-(Carboxymethyl)-L-lysine

1 Publications Verification

CML; N6-(carboxymethyl)-L-lysine; Nε-(1-carboxymethyl)-L-lysine

Biochemical Assay Reagents

Nε-(Carboxymethyl)-L-lysine (CML) is an orally active advanced glycation end product. Nε-(Carboxymethyl)-L-lysine upregulates the expression of PLK1 and CEP20, and induces the activation of RAGE and ERK/NFκB. Nε-(Carboxymethyl)-L-lysine drives centrosome amplification. Nε-(Carboxymethyl)-L-lysine induces malignant transformation of hepatocytes and promotes the development of hepatocellular carcinoma. Nε-(Carboxymethyl)-L-lysine induces epithelial-mesenchymal transition in osteosarcoma cells and enhances their migration and invasion properties .

HY-Y0703A

*Sodium carboxymethyl* cellulose (Viscosity:1200-1400 mPa.s)** CMC-Na (Viscosity:1200-1400 mPa.s)	Biochemical Assay Reagents
Sodium carboxymethyl cellulose (Viscosity:1200-1400 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

HY-Y1889

*Sodium carboxymethyl* cellulose (Viscosity:5000-15000 mPa.s)** CMC-Na (Viscosity:5000-15000 mPa.s)	Biochemical Assay Reagents
Sodium carboxymethyl cellulose (Viscosity:5000-15000 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

HY-Y0703D

*Sodium carboxymethyl* cellulose (average Mw 90000)** CMC-Na (average Mw 90000, DS=0.7, Viscosity:50-200 mPa.s)	Biochemical Assay Reagents
Sodium carboxymethyl cellulose (average Mw 90000, DS=0.7, Viscosity:50-200 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent .

HY-B2221C

CM Cellulose CM-32

carboxymethyl cellulose CM-32; CM-32

Biochemical Assay Reagents

CM Cellulose CM-32 (Carboxymethyl cellulose) is a cellulose derivative. CM Cellulose CM-32 has a wide range of applications in the biomedical field, including tissue engineering, wound dressing, absorbent nonwovens, fabrication of 3D-scaffolds for biocompatible implants, artificial organs or mimics of extracellular polymeric matrix and diagnosis of various diseases. CM Cellulose CM-32 can decrease osteoclasts formation. CM Cellulose CM-32 can be used as a biological material or organic compound for life science related research .

HY-W004761

Tetrahydroxydiboron

Hypodiboric acid

Biochemical Assay Reagents

Tetrahydroxydiboron acts as a hydrogel initiator and bioadhesion promoter, with broad-spectrum antibacterial activity, ROS scavenging capacity and osteogenic induction properties. Tetrahydroxydiboron initiates rapid gelation by generating free radicals through reactions with vinyl monomers and dissolved oxygen, and overcomes oxygen inhibition without deoxygenation or external triggers. Tetrahydroxydiboron achieves strong bioadhesion through interaction with carboxymethyl chitosan. Tetrahydroxydiboron can be used in the research of periodontitis and related inflammatory diseases .

HY-D0980

Biotin-DADOO

Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin

Biochemical Assay Reagents

Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin) is a biotin-containing amine compound and a biotinylation reagent. As an amino component, Biotin-DADOO participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. Biotin-DADOO can be conjugated with carboxymethyl cellulose derivatives. Biotin-DADOO is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A .

HY-126393

Carboxymethyl-β-cyclodextrin	Biochemical Assay Reagents
Carboxymethyl-β-cyclodextrin is a cationic cyclodextrin used as a carrier for drugs. It has been shown to bind nonsteroidal anti-inflammatory drugs (NSAIDs) with high affinity and selectivity.

HY-Y0703E

*Sodium carboxymethyl* cellulose (Viscosity:2500-6000mpa.s)**	Biochemical Assay Reagents
Sodium carboxymethyl cellulose (Viscosity:2500-6000mpa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent .

HY-W1048555A

Mal-PEG2000-SCM

Biochemical Assay Reagents

Mal-PEG2000-SCM is a heterobifunctional PEG crosslinker bearing maleimide and succinimidyl carboxymethyl ester functional groups. MMal-PEG2000-SCM conjugates the F3 peptide to nanoparticles: the SCM group reacts with amino groups on the nanoparticle surface to form amide groups, while the MAL group reacts with thiol groups of the F3 peptide to form carbon-sulfur bonds. Mal-PEG-SCM enables unidirectional addition of linkers, ensuring that appropriate functional groups are available for RGD incorporation. Mal-PEG2000-SCM can be used in the development of nanoparticles targeting specific tumor cells .

HY-158223

Carboxymethyl chitosan Methacryloyl

CMCSMA

Biochemical Assay Reagents

Carboxymethyl chitosan Methacryloyl (CMCSMA) is methacrylated carboxymethyl chitosan with properties as a 3D printing ink. A composite hydrogel made of Carboxymethyl chitosan Methacryloyl can effectively accelerate bone healing in an infectious microenvironment after implantation in a rat model of Staphylococcus aureus-infected femoral defect . Carboxymethyl chitosan Methacryloyl needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.

HY-W127837

2-Aminooxyethyliminodiacetic acid hydrochloride N-[2-(AMinooxy)ethyl]-N-(carboxymethyl)glycine hydrochloride	Biochemical Assay Reagents
2-Aminooxyethyliminodiacetic Acid Hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W1048555B

Mal-PEG3400-SCM

Biochemical Assay Reagents

Mal-PEG3400-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG3400-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .

HY-W093254A

*Poly(ethylene glycol) bis(carboxymethyl) ether (MW 250)*	Biochemical Assay Reagents
Poly(ethylene glycol) bis(carboxymethyl) ether (MW 250) is an amine-reactive crosslinking agent .

HY-W093254B

*Poly(ethylene glycol) bis(carboxymethyl) ether (MW 600)*	Biochemical Assay Reagents
Poly(ethylene glycol) bis(carboxymethyl) ether (MW 600) is an amine-reactive crosslinking agent .

HY-W1049024

N3-PEG2000-SCM Azide PEG2000 Succinimidyl carboxymethyl Ester	Biochemical Assay Reagents
N3-PEG2000-SCM (Azide PEG2000 Succinimidyl Carboxymethyl Ester) is a linear heteroterminal bifunctional PEG product with succinimidyl carbonate and azide groups.

HY-W1049024A

N3-PEG5000-SCM Azide PEG5000 Succinimidyl carboxymethyl Ester	Biochemical Assay Reagents
N3-PEG5000-SCM (Azide PEG5000 Succinimidyl Carboxymethyl Ester) is a linear heteroterminal bifunctional PEG product with succinimidyl carbonate and azide groups.

HY-W1049071D

HO-PEG40000-SCM	Biochemical Assay Reagents
HO-PEG40000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.

HY-W1048555D

Mal-PEG10000-SCM

Biochemical Assay Reagents

Mal-PEG10000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG10000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .

HY-W1048555

Mal-PEG1000-SCM

Biochemical Assay Reagents

Mal-PEG1000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG1000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .

HY-W1049024B

N3-PEG10000-SCM Azide PEG10000 Succinimidyl carboxymethyl Ester	Biochemical Assay Reagents
N3-PEG10000-SCM (Azide PEG10000 Succinimidyl Carboxymethyl Ester) is a linear heteroterminal bifunctional PEG product with succinimidyl carbonate and azide groups.

HY-W1049024C

N3-PEG20000-SCM Azide PEG20000 Succinimidyl carboxymethyl Ester	Biochemical Assay Reagents
N3-PEG20000-SCM (Azide PEG20000 Succinimidyl Carboxymethyl Ester) is a linear heteroterminal bifunctional PEG product with succinimidyl carbonate and azide groups.

HY-W1049024H

N3-PEG3400-SCM Azide PEG3400 Succinimidyl carboxymethyl Ester	Biochemical Assay Reagents
N3-PEG3400-SCM (Azide PEG3400 Succinimidyl Carboxymethyl Ester) is a linear heteroterminal bifunctional PEG product with succinimidyl carbonate and azide groups.

HY-W1049024E

N3-PEG1000-SCM Azide PEG1000 Succinimidyl carboxymethyl Ester	Biochemical Assay Reagents
N3-PEG1000-SCM (Azide PEG1000 Succinimidyl Carboxymethyl Ester) is a linear heteroterminal bifunctional PEG product with succinimidyl carbonate and azide groups.

HY-W1049024D

N3-PEG40000-SCM Azide PEG40000 Succinimidyl carboxymethyl Ester	Biochemical Assay Reagents
N3-PEG40000-SCM (Azide PEG40000 Succinimidyl Carboxymethyl Ester) is a linear heteroterminal bifunctional PEG product with succinimidyl carbonate and azide groups.

HY-179067

CM-Polysucrose 70	Biochemical Assay Reagents
CM-Polysucrose 70 consists of polysucrose substituted with carboxymethyl groups, which imparts polyanionic properties to the product .

HY-W1049071H

HO-PEG2000-SCM	Biochemical Assay Reagents
HO-PEG2000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.

HY-W1049071C

HO-PEG20000-SCM	Biochemical Assay Reagents
HO-PEG20000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.

HY-W1049071A

HO-PEG5000-SCM	Biochemical Assay Reagents
HO-PEG5000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.

HY-W1049071I

HO-PEG3400-SCM	Biochemical Assay Reagents
HO-PEG3400-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.

HY-W1049071B

HO-PEG10000-SCM	Biochemical Assay Reagents
HO-PEG10000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.

HY-W1049071E

HO-PEG1000-SCM	Biochemical Assay Reagents
HO-PEG1000-SCM is a hetero-bifunctional hydroxy PEG succinimidyl carboxymethyl ester product, which is commonly used as a cross-linker or spacer between two different chemical entities.

HY-179068

FITC-CM-Polysucrose 70	Biochemical Assay Reagents
FITC-CM-Polysucrose 70 is FITC-labeled CM-Polysucrose 70 (HY-179067). CM-Polysucrose 70 consists of polysucrose substituted with carboxymethyl groups, which imparts polyanionic properties to the product. FITC-CM-Polysucrose 70 is primarily used in permeability and microcirculatory studies (Ex/Em = 488/525 nm) .

HY-W1048555H

Mal-PEG40000-SCM

Biochemical Assay Reagents

Mal-PEG40000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG40000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .

HY-W1048555C

Mal-PEG5000-SCM

Biochemical Assay Reagents

Mal-PEG5000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG5000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .

HY-W1048555E

Mal-PEG20000-SCM

Biochemical Assay Reagents

Mal-PEG20000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG20000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .

Cat. No.	Product Name	Target	Research Area

HY-134124

*Glutathione ethyl* ester**	Reactive Oxygen Species (ROS)	Metabolic Disease
Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-100047

*Nα,Nα-Bis(carboxymethyl)-L-lysine*	Taste Receptor	Others
Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC₅₀ of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study .

HY-P1108A

Astressin 2B TFA 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B TFA blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B TFA reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B TFA also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B TFA mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B TFA is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .

HY-P1108

Astressin 2B 1 Publications Verification	CRFR	Neurological Disease Inflammation/Immunology
Astressin 2B is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist (rCRFR2, IC₅₀=0.57 nM). Astressin 2B blocks the protective effects mediated by CRFR2, thereby exacerbating indomethacin (HY-14397)-induced hemorrhagic intestinal injury in rats. Astressin 2B reverses the protective effects of Urocortin 1 against intestinal hypermotility, bacterial invasion and upregulation of inflammatory mediators. Astressin 2B also blocks the anxiogenic effect of Urocortin 2 and attenuates stress-induced anxiety-related behaviors. In the Clostridioides difficile toxin A (C. difficile toxin A)-mediated enteritis model, Astressin 2B mimics the phenotype of CRFR2-deficient mice, significantly exacerbating intestinal epithelial damage, edema, neutrophil migration and the expression of multiple proinflammatory cytokines. Astressin 2B is an important tool molecule for investigating the intestinal protective mechanisms of CRFR2 .

HY-114118S1

Semaglutide-d8 tetraTFA	Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family	Neurological Disease Metabolic Disease Cancer
Semaglutide-d₈ tetraTFA is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .

HY-114118S

Semaglutide-d8	Isotope-Labeled Compounds GLP Receptor Insulin Receptor α-synuclein Apoptosis p38 MAPK Autophagy Bcl-2 Family	Neurological Disease Metabolic Disease Cancer
Semaglutide-d₈ is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .

HY-P2336A

CCZ01048 TFA 3 Publications Verification	Melanocortin Receptor	Cancer
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .

HY-P10143

MMP-2/MMP-9 Substrate Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt	MMP	Others
MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .

HY-A0248AS

Polymyxin B1-d7 TFA	Isotope-Labeled Compounds Bacterial	Infection
Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

HY-P3066

SKF 100398 d(CH2)5Tyr(Et)VAVP	Vasopressin Receptor	Metabolic Disease
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .

HY-W009913

*2-((Carboxymethyl)amino)benzoic acid*	Amino Acid Derivatives	Others
2-((Carboxymethyl)amino)benzoic acid is a Glycine (HY-Y0966) derivative .

HY-P10828

MAPI	Virus Protease	Infection Inflammation/Immunology
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .

HY-P4756

*N-(2-Carbamoyl-ethyl)-Val-Leu-anilide*	Peptides	Others
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P2592

Ro 23-7014	Cholecystokinin Receptor	Others
Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .

HY-125628

Kahalalide A	Endogenous Metabolite	Infection
Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .

HY-100047R

*Nα,Nα-Bis(carboxymethyl)-L-lysine (Standard)*	Taste Receptor Reference Standards	Others
Nα,Nα-Bis(carboxymethyl)-L-lysine (Standard) is the analytical standard of Nα,Nα-Bis(carboxymethyl)-L-lysine (HY-100047). This product is intended for research and analytical applications. Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study .

HY-A0248AS1

Polymyxin B1-D-Leu-d7 TFA	Isotope-Labeled Compounds Bacterial	Infection
Polymyxin B1-D-Leu-d₇ TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-A0248A

Polymyxin B1 1 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-A0248AS

Polymyxin B1-d7 TFA	Structural Classification Microorganisms Antibiotics Antibacterial Disease Research Other Antibiotics Source Classification	Isotope-Labeled Compounds Bacterial
Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-A0248AS1

Polymyxin B1-D-Leu-d7 TFA	Structural Classification Microorganisms Antibiotics Antibacterial Disease Research Other Antibiotics Source Classification	Isotope-Labeled Compounds Bacterial
Polymyxin B1-D-Leu-d₇ TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

Cat. No.	Product Name	Chemical Structure

HY-114118S1

Semaglutide-d8 tetraTFA

Semaglutide-d₈ tetraTFA is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .

HY-114118S

Semaglutide-d8

Semaglutide-d₈ is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .

HY-A0248AS

Polymyxin B1-d7 TFA

Polymyxin B1-d₇ TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

HY-W286743S1

CML-d3
CML-d₃ is the deuterium labeled CML.

HY-W587411S

*Mono[2-(carboxymethyl)hexyl] phthalate-d4*
Mono[2-(carboxymethyl)hexyl] phthalate-d₄ is a deuterium labeled compound.

HY-A0248AS1

Polymyxin B1-D-Leu-d7 TFA

Polymyxin B1-D-Leu-d₇ TFA is the deuterium labeled Polymyxin B1 (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

Cat. No.	Product Name		Classification

HY-Y0703

*Sodium carboxymethyl* cellulose (Viscosity:800-1200 mPa.s)** 45+ Cited Publications CMC-Na (Viscosity:800-1200 mPa.s)		Binders Disintegrants Suspending Agents
Sodium carboxymethyl cellulose (Viscosity:800-1200 mPa.s) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

HY-154704

*Calcium carboxymethyl* cellulose**		Disintegrants
Calcium carboxymethyl cellulose can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-152465

*5-Carboxymethyl-2-thiouridine*		Nucleoside Analogs Uridine
5-Carboxymethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

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