4-(Carboxymethyl)phenylboronic acid pinacol ester
Based on 1 Customer Validation
4-(Carboxymethyl)phenylboronic acid pinacol ester is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 797755-07-8
- Formula: C14H19BO4
- Molecular Weight:262.11
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E353 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 797755-07-8
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Appearance Solid
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Molecular Weight 262.11
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Formula C14H19BO4
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Color White to off-white
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SMILES
O=C(O)CC1=CC=C(C=C1)B2OC(C)(C)C(O2)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 100 mg/mL (381.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (243 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8152 mL | 19.0760 mL | 38.1519 mL | 95.3798 mL |
| 5 mM | 0.7630 mL | 3.8152 mL | 7.6304 mL | 19.0760 mL | |
| 10 mM | 0.3815 mL | 1.9076 mL | 3.8152 mL | 9.5380 mL | |
| 15 mM | 0.2543 mL | 1.2717 mL | 2.5435 mL | 6.3587 mL | |
| 20 mM | 0.1908 mL | 0.9538 mL | 1.9076 mL | 4.7690 mL | |
| 25 mM | 0.1526 mL | 0.7630 mL | 1.5261 mL | 3.8152 mL | |
| 30 mM | 0.1272 mL | 0.6359 mL | 1.2717 mL | 3.1793 mL | |
| 40 mM | 0.0954 mL | 0.4769 mL | 0.9538 mL | 2.3845 mL | |
| 50 mM | 0.0763 mL | 0.3815 mL | 0.7630 mL | 1.9076 mL | |
| 60 mM | 0.0636 mL | 0.3179 mL | 0.6359 mL | 1.5897 mL | |
| 80 mM | 0.0477 mL | 0.2384 mL | 0.4769 mL | 1.1922 mL | |
| 100 mM | 0.0382 mL | 0.1908 mL | 0.3815 mL | 0.9538 mL |