1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester
Based on 1 Customer Validation
1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester is a drug intermediate that can be used for the preparation of SMARCA bromodomain ligands.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 286961-14-6
- Formula: C16H28BNO4
- Molecular Weight:309.21
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester (Compound 35) introduces the key Boc-piperidine structural motif into the target molecular scaffold via two efficient reactions (Suzuki coupling + catalytic hydrogenation)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 286961-14-6
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Appearance Solid
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Molecular Weight 309.21
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Formula C16H28BNO4
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Color White to off-white
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SMILES
O=C(OC(C)(C)C)N1CCC(B(OC(C)2C)OC2(C)C)=CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 5 mg/mL (16.17 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2340 mL | 16.1702 mL | 32.3405 mL | 80.8512 mL |
| 5 mM | 0.6468 mL | 3.2340 mL | 6.4681 mL | 16.1702 mL | |
| 10 mM | 0.3234 mL | 1.6170 mL | 3.2340 mL | 8.0851 mL | |
| 15 mM | 0.2156 mL | 1.0780 mL | 2.1560 mL | 5.3901 mL |
1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester Related Classifications
HY-40249 Related Classifications
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