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  4. Mal-PEG2000-SCM

Mal-PEG2000-SCM is a heterobifunctional PEG crosslinker bearing maleimide and succinimidyl carboxymethyl ester functional groups. MMal-PEG2000-SCM conjugates the F3 peptide to nanoparticles: the SCM group reacts with amino groups on the nanoparticle surface to form amide groups, while the MAL group reacts with thiol groups of the F3 peptide to form carbon-sulfur bonds. Mal-PEG-SCM enables unidirectional addition of linkers, ensuring that appropriate functional groups are available for RGD incorporation. Mal-PEG2000-SCM can be used in the development of nanoparticles targeting specific tumor cells.

For research use only. We do not sell to patients.

Mal-PEG2000-SCM

Mal-PEG2000-SCM Chemical Structure

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Based on 1 publication(s) in Google Scholar

Mal-PEG2000-SCM Related Antibodies

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Description

Mal-PEG2000-SCM is a heterobifunctional PEG crosslinker bearing maleimide and succinimidyl carboxymethyl ester functional groups. MMal-PEG2000-SCM conjugates the F3 peptide to nanoparticles: the SCM group reacts with amino groups on the nanoparticle surface to form amide groups, while the MAL group reacts with thiol groups of the F3 peptide to form carbon-sulfur bonds. Mal-PEG-SCM enables unidirectional addition of linkers, ensuring that appropriate functional groups are available for RGD incorporation. Mal-PEG2000-SCM can be used in the development of nanoparticles targeting specific tumor cells[1][2].

In Vitro

Mal-PEG-SCM enables one-way addition of linkers, ensuring that appropriate functional groups are available for RGD conjugation[1].
Mal-PEG2000-SCM conjugates the F3 peptide to nanoparticles. The SCM group reacts with amino groups on the nanoparticle surface to form amide groups, while the MAL group reacts with thiol groups of the F3 peptide to form carbon-sulfur bonds[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Mal-PEG2000-SCM Related Antibodies
Molecular Weight

2000 (Average)

Appearance

Solid

Color

White to off-white

SMILES

O=C(COCCOCCNC(CCN1C(C=CC1=O)=O)=O)ON(C2=O)C(CC2)=O.[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation
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Mal-PEG2000-SCM Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mal-PEG2000-SCMBiochemical Assay Reagentsage-related macular degenerationthiol groupschoroidal neovascularization macular degenerationamine groups8-arm PEG particlesmaleimideF3 peptidessuccinimidyl carboxy methyl esterpolyacrylamide nanoparticlesRGD peptidesInhibitorinhibitorinhibit

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