1. Anti-infection
  2. HCV
  3. Monodes(N-carboxymethyl)valine Daclatasvir

Monodes(N-carboxymethyl)valine Daclatasvir  (Synonyms: Daclatasvir Impurity A)

Cat. No.: HY-133246
Handling Instructions

Monodes(N-carboxymethyl)valine Daclatasvir (Daclatasvir Impurity A) is the main degradation product of Daclatasvir. Daclatasvir is a potent HCV NS5A protein inhibitor.

For research use only. We do not sell to patients.

Monodes(N-carboxymethyl)valine Daclatasvir Chemical Structure

Monodes(N-carboxymethyl)valine Daclatasvir Chemical Structure

CAS No. : 1007884-60-7

Size Price Stock
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 512 Ask For Quote & Lead Time
Solution
10 mM * 1 mL in DMSO USD 512 Ask For Quote & Lead Time
Solid
5 mg USD 400 Ask For Quote & Lead Time
10 mg USD 680 Ask For Quote & Lead Time

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Description

Monodes(N-carboxymethyl)valine Daclatasvir (Daclatasvir Impurity A) is the main degradation product of Daclatasvir. Daclatasvir is a potent HCV NS5A protein inhibitor[1].

Molecular Weight

581.71

Formula

C33H39N7O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

COC(N[C@@H](C(C)C)C(N(CCC1)[C@@H]1C2=NC(C3=CC=C(C4=CC=C(C5=CNC([C@H]6NCCC6)=N5)C=C4)C=C3)=CN2)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (429.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7191 mL 8.5953 mL 17.1907 mL
5 mM 0.3438 mL 1.7191 mL 3.4381 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7191 mL 8.5953 mL 17.1907 mL 42.9767 mL
5 mM 0.3438 mL 1.7191 mL 3.4381 mL 8.5953 mL
10 mM 0.1719 mL 0.8595 mL 1.7191 mL 4.2977 mL
15 mM 0.1146 mL 0.5730 mL 1.1460 mL 2.8651 mL
20 mM 0.0860 mL 0.4298 mL 0.8595 mL 2.1488 mL
25 mM 0.0688 mL 0.3438 mL 0.6876 mL 1.7191 mL
30 mM 0.0573 mL 0.2865 mL 0.5730 mL 1.4326 mL
40 mM 0.0430 mL 0.2149 mL 0.4298 mL 1.0744 mL
50 mM 0.0344 mL 0.1719 mL 0.3438 mL 0.8595 mL
60 mM 0.0287 mL 0.1433 mL 0.2865 mL 0.7163 mL
80 mM 0.0215 mL 0.1074 mL 0.2149 mL 0.5372 mL
100 mM 0.0172 mL 0.0860 mL 0.1719 mL 0.4298 mL
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Monodes(N-carboxymethyl)valine Daclatasvir Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Monodes(N-carboxymethyl)valine Daclatasvir
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