2. Anti-infection
  3. HCV
  4. Sofosbuvir impurity N

Sofosbuvir impurity N, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.

For research use only. We do not sell to patients.

Sofosbuvir impurity N Chemical Structure

Sofosbuvir impurity N Chemical Structure

CAS No. : 1394157-34-6

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1 mg USD 900 In-stock
5 mg USD 2250 In-stock
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Based on 1 publication(s) in Google Scholar

Sofosbuvir impurity N Related Antibodies

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Description

Sofosbuvir impurity N, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.

IC50 & Target

HCV[1]
Molecular Weight

501.40

Formula

C20H25FN3O9P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=[P@@](N[C@@H](C)C(OC)=O)(OC[C@@H]1[C@@H](O)[C@](F)(C)[C@H](N2C=CC(NC2=O)=O)O1)OC3=CC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (199.44 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9944 mL 9.9721 mL 19.9442 mL
5 mM 0.3989 mL 1.9944 mL 3.9888 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9944 mL 9.9721 mL 19.9442 mL 49.8604 mL
5 mM 0.3989 mL 1.9944 mL 3.9888 mL 9.9721 mL
10 mM 0.1994 mL 0.9972 mL 1.9944 mL 4.9860 mL
15 mM 0.1330 mL 0.6648 mL 1.3296 mL 3.3240 mL
20 mM 0.0997 mL 0.4986 mL 0.9972 mL 2.4930 mL
25 mM 0.0798 mL 0.3989 mL 0.7978 mL 1.9944 mL
30 mM 0.0665 mL 0.3324 mL 0.6648 mL 1.6620 mL
40 mM 0.0499 mL 0.2493 mL 0.4986 mL 1.2465 mL
50 mM 0.0399 mL 0.1994 mL 0.3989 mL 0.9972 mL
60 mM 0.0332 mL 0.1662 mL 0.3324 mL 0.8310 mL
80 mM 0.0249 mL 0.1247 mL 0.2493 mL 0.6233 mL
100 mM 0.0199 mL 0.0997 mL 0.1994 mL 0.4986 mL
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Sofosbuvir impurity N Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sofosbuvir impurity N1394157-34-6HCVHepatitis C virusInhibitorinhibitorinhibit

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