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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
59 Results for "
coronary heart disease
" in MedChemExpress (MCE) Product Catalog:
Products (59)
59 Results for "coronary heart disease" in MCE Product Catalog:
6
6 Publications Verification
Cat. No.: HY-B0203A
CAS No.: 152520-56-4
Synonyms: R 065824 hydrochloride
Target:
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Nebivolol (R 065824) hydrochloride is an orally active beta receptor blocker and has the high beta(1)-receptor affinity.Nebivolol hydrochloride has direct vasodilator properties and adrenergic blocking characteristics. Nebivolol hydrochloride can be used for the research of kinds of diseases such as hypertension, coronary artery disease, congestive heart failure and ischemic heart disease .
6
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Nebivolol (R 065824) is an orally active beta receptor blocker and has the high beta(1)-receptor affinity. Nebivolol has direct vasodilator properties and adrenergic blocking characteristics. Nebivolol can be used for the research of kinds of diseases such as hypertension, coronary artery disease, congestive heart failure and ischemic heart disease .
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3
3 Cited Publications
Cat. No.: HY-W004284
CAS No.: 506-12-7
Category:
Cardiovascular Disease Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
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1
1
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Mitiperstat (AZD4831) is an effective oral inhibitor of myeloperoxidase (MPO). Mitiperstat inhibits MPO and thyroid peroxidase (TPO) with IC50s of 1.5 nM and 0.69 μM. Mitiperstat exhibits a weak inhibitory activity against CYP3A4 with an IC50 of 6 μM. Mitiperstat can reduce inflammation and improve microvascular function, and it can be used in studies related to heart failure, preserved or mildly reduced ejection fraction, non-alcoholic fatty liver disease, and chronic obstructive pulmonary disease .
1
1 Cited Publications
Cat. No.: HY-N5139
CAS No.: 93685-90-6
Synonyms: Lecithins, egg yolk; Belovo PL 85
Research Areas:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology
Lecithins, egg (Lecithins, egg yolk; Belovo PL 85) is an orally active natural phospholipid mixture extracted from egg yolks . Lecithins, egg inhibits the activities of acetylcholinesterase (AChE) and angiotensin-converting enzyme (ACE). Lecithins, egg exhibits antibacterial, antioxidant and anti-inflammatory activities, and helps delay cellular senescence. Lecithins, egg enhances nerve conduction, improves memory and cognitive function, and exerts positive effects on delaying neurodegenerative diseases. Lecithins, egg promotes lipid absorption and alleviates diarrhea. Lecithins, egg acts as a high-efficiency drug carrier for the preparation of targeted drug delivery systems such as liposomes .
1
1 Cited Publications
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SKA-111 is a selective activator of potassium phannel KCa 3.1 , evokes KCa 3.1 membrane hyperpolarization in porcine endothelial cell. SKA-111 is capable of improving Bradykinin (HY-P0206)-induced coronary dilations in the isolated rat heart and can be used for cardiovascular disease research .
Cat. No.: HY-P4153
CAS No.: 2407527-16-4
Synonyms: MK-0616 chloride
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Cat. No.: HY-N1179
CAS No.: 17397-93-2
Category:
Cardiovascular Disease Quinones Neurological Disease Labiatae Samanea saman (Jacq.) Merr. Plants Disease Research Fields Naphthalene Quinones
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Synonyms: SLPC; 18:0-18:2 PC
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Cat. No.: HY-130245
Purity: 98.33%
Research Areas:
PCSK9 degrader 1 is a HyT-like PCSK9 degrader with a Ki of 107 nM. PCSK9 degrader 1 binds to the allosteric pocket between the catalytic domain and C-terminal domain of PCSK9. While maintaining key interactions with this protein, it extends the proteasome-recruiting moiety, thereby driving degradation via the proteasomal pathway. PCSK9 degrader 1 induces the degradation of both the precursor and mature forms of PCSK9, with DC50 values of 4.8 μM and 3.4 μM respectively, and does not significantly affect cell viability or the expression of housekeeping proteins. PCSK9 degrader 1 can be used in the research of coronary heart disease .
Cat. No.: HY-W004284S
CAS No.: 202528-95-8
Cat. No.: HY-W004284S1
CAS No.: 352431-41-5
Cat. No.: HY-N2509
CAS No.: 86849-77-6
Synonyms: Iristectrigenin B
Category:
Cardiovascular Disease Natural Products Iridaceae Phenols Polyphenols Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields
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MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA) MMP-2 inhibitor(IC50=6.6 μM) and can be used for the study of acute myocardial infarction. MMPI-1154 also inhibits the activity of MMP-13, MMP-1 and MMP-9 with IC50s of 1.8 μM,10 μM, and 13 μM, respectively .
Cat. No.: HY-W004284R
CAS No.: 506-12-7
Target:
Cat. No.: HY-P991574
CAS No.: 2643310-75-0
Synonyms: REG-101
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Cat. No.: HY-142117S
Purity: 99.25%
Cat. No.: HY-P11071
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
