4-Amino-N-methylphthalimide
Based on 1 Customer Validation
4-Amino-N-methylphthalimide (Compound 13) is an angiogenesis regulator and Thalidomide (HY-14658) derivative. 4-Amino-N-methylphthalimide exerts a bidirectional regulatory (inhibitory or promotive) effect on the proliferation of vascular endothelial cells. 4-Amino-N-methylphthalimide is applicable to the research of coronary heart disease.
For research use only. We do not sell to patients.
- CAS No.: 2307-00-8
- Formula: C9H8N2O2
- Molecular Weight:176.18
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Storage:
RT, protect from light.
In solvent -80°C, 1 year , -20°C, 6 months
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
4-Amino-N-methylphthalimide (38.5-385 μM; 20 h) modulates HUVEC proliferation, with a 31.32% increase at 192.5 μM and a 17.61% inhibition at 385 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human umbilical vein endothelial cells
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Concentration:38.5-385 μM
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Incubation Time:20 h
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Result:Caused 17.61% inhibition of endothelial cell proliferation relative to 10% serum control at 385 μM.
Caused 4.39% inhibition at 289 μM.
Induced 31.32% increase in proliferation at 192.5 μM.
Caused 2.36% inhibition at 96 μM.
Induced 6.72% increase in proliferation at 38.5 μM.
Chemical Information
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CAS No. 2307-00-8
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Appearance Solid
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Molecular Weight 176.18
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Formula C9H8N2O2
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SMILES
O=C1C2=CC=C(N)C=C2C(=O)N1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, protect from light
In solvent -80°C 1 year -20°C 6 months
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Amino-N-methylphthalimide Related Classifications
HY-W032902 Related Classifications
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