89 Results for "

cysteine (Cys)

" in MedChemExpress (MCE) Product Catalog:
Products (89)

89 Results for "cysteine (Cys)" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-139093A
CAS No.: 1331891-93-0
Purity:  ≥99.0%
Synonyms: APAP-Cys TFA
Target:  

Drug Derivative

Research Areas:  

Others

Paracetamol-cysteine TFA (APAP-Cys TFA) is a cysteine adduct of Acetaminophen (HY-66005). It forms when Acetaminophen is oxidized to the reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI) .
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1
1 Cited Publications
Cat. No.: HY-D2186
CAS No.: 2095485-22-4
BTD probe-1 is a benzothiazine-based chemoproteomic probe and selective protein S-sulfenic acid (Cys-SOH) labeling agent. BTD probe-1 labels protein S-sulfenic acids in vitro in cell and tissue samples, and in situ in intact cells, enabling detection or enrichment of modified proteins/peptides. BTD probe-1 exhibits no cytotoxicity in cells at concentrations ≤1 mM. BTD probe-1 enables global, site-specific mapping and quantification of cysteine S-sulfenylation in complex proteomes with lower input material .
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Cat. No.: HY-W007798
CAS No.: 103213-32-7
Research Areas:  

Others

Fmoc-Cys(Trt)-OH is a cysteine derivative .
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Cat. No.: HY-P1351
CAS No.: 906480-09-9
Research Areas:  

Cancer

Angiopep-2-cys is a conjugate of Angiopep-2 hydrochloride (HY-P2341) and cysteine. Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer .
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Cat. No.: HY-113110
CAS No.: 19246-18-5
Purity:  99.96%
Synonyms: L-Cysteinylglycine; Cys-Gly; H-Cys-Gly-OH
Cysteinylglycine (L-Cysteinylglycine; Cys-Gly) is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron, drives the redox cycle of iron, generates reactive oxygen species (ROS), stimulates oxidative reactions, induces lipid peroxidation of human plasma LDL lipoproteins, and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease, breast cancer and other conditions .
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Cat. No.: HY-W013143
CAS No.: 86060-81-3
Research Areas:  

Others

Fmoc-Cys(Acm)-OH is a cysteine derivative .
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Cat. No.: HY-P4093
CAS No.: 209323-98-8
Research Areas:  

Others

Cys-Penetratin is a cysteine-containing cell-penetrating peptide with sequence CRQIKIWFQNRRMKWKK. Cys-Penetratin can Cys-Penetratin can be used for the research for the research of drug delivery .
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Cat. No.: HY-176415
CAS No.: 3025787-83-8
Research Areas:  

Cancer

Cys-MC-GGFG-Dxd is a cysteine-modified, cleavable ADC drug-linker conjugate. Cys-MC-GGFG-Dxd consists of a maleimidocaproyl-glycine-glycine-L-phenylalanine-glycine (MC-GGFG) linker and an Exatecan (HY-13631) derivative (DXd) (HY-13631D) payload. Cys-MC-GGFG-Dxd can be further conjugated to anti-HER2 IgG1κ antibody for the synthesis of antibody-drug conjugates (ADC), such as the breast cancer-targeting ADC compound Fam-trastuzumab deruxtecan-nxki (Enhertu) .
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Cat. No.: HY-165613
CAS No.: 656831-18-4
Synonyms: Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine
Pam2Cys (Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine) is a TLR2 agonist and immunostimulant. Pam2Cys binds to TLR2 to activate dendritic cells and trigger the TLR2-dependent NF-κB signaling pathway. Pam2Cys also induces dendritic cell maturation by upregulating the expression of cell surface MHC II molecules. Pam2Cys activates innate immune signaling pathways, drives pro-inflammatory and antimicrobial responses, enhances the expression of macrophage activation markers, increases phagocytic activity, induces the release of IL-12 and pro-inflammatory cytokines, and polarizes macrophages into a pro-inflammatory, antimicrobial phenotype without interfering with IL-10-induced macrophage polarization. Pam2Cys also serves as the lipid moiety in synthetic lipopeptide vaccines and possesses self-adjuvant properties. Pam2Cys enhances the immunogenicity of conjugated peptide segments and induces cellular and humoral immune responses. However, it does not activate CD4 T cells in mouse splenocyte cultures when used alone. Pam2Cys activates pulmonary TLR2 signaling pathways, triggers innate immune responses, recruits neutrophils and macrophages, induces the secretion of various cytokines, alleviates symptoms and damages associated with influenza A virus infection in mice without impairing adaptive immunity. Pam2Cys can be used in studies related to tuberculosis and influenza A virus infection .
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Cat. No.: HY-P11308
CAS No.: 1421680-54-7
Target:  

EGFR

Research Areas:  

Cancer

Cys-GE11 is an N-terminal modified GE11 (HY-P10128) with cysteine ​​(Cys) added. Cys-GE11 can be coupled through the thiol group of Cys. Cys-GE11 can be linked to PEG-P (TMC-DTC) through the N-terminus of cysteine to form a targeted polymer. Cys-GE11 can target cells with high EGFR expression (such as SMMC-7721 cells). Cys-GE11 can significantly enhance drug enrichment at the tumor site and exhibit low toxicity .
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Cat. No.: HY-114788
CAS No.: 106325-92-2
Synonyms: L-Lysyl-L-cysteine; Lys-Cys; H-Lys-Cys-OH
Research Areas:  

Others

Lysylcysteine (L-Lysyl-L-cysteine) is a dipeptide composed of lysine and cysteine. Lysylcysteine can be used for the synthesis of the antioxidant Lys-Cys-His-Lys-Pro (KCHKP) .
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Cat. No.: HY-W010724
CAS No.: 167015-11-4
Research Areas:  

Others

Fmoc-D-Cys(Trt)-OH is a cysteine derivative .
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Cat. No.: HY-W101367
CAS No.: 19542-77-9
Synonyms: N-Acetyl-S-benzyl-L-cysteine; Benzylmercapturic acid
Target:  

Drug Metabolite

Research Areas:  

Others

Ac-Cys(Bzl)-OH (N-Acetyl-S-benzyl-L-cysteine) is a toluene metabolite. Ac-Cys(Bzl)-OH in urine samples is a good marker of occupational toluene exposure.
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Cat. No.: HY-134852
CAS No.: 1403834-74-1
Research Areas:  

Others

Fmoc-Cys(STmp)-OH is a cysteine derivative .
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Cat. No.: HY-W012075
CAS No.: 2544-31-2
Research Areas:  

Others

H-Cys(pMeOBzl)-OH is a cysteine derivative .
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Cat. No.: HY-W069127F
Synonyms: Bio-ben
Research Areas:  

Others

Biotin-benzoboroxole (Bio-ben) is a functional probe for the detection of cysteine sulfenic acid (Cys-SOH) .
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Cat. No.: HY-D2315
Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cysteine (Cys) (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant DTT (HY-15917) and the NEM (HY-D0843) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .
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Cat. No.: HY-P1801A
Synonyms: Cys-[HIV-Tat (47-57)] TFA
Target:  

HIV Drug Derivative

Research Areas:  

Others

Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) TFA, TAT (HY-P0281) derivative, is a Cysteine (HY-Y0337)-tagged cell-penetrating peptide (CPP) derived from the HIV TAT protein. Cys-TAT(47-57) TFA can be used for the research for the research of drug delivery .
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Cat. No.: HY-P4087
CAS No.: 1417221-06-7
Target:  

HIV

Research Areas:  

Infection Cancer

Cys(Npys)-(Arg)9 is a synthetic cationic cell-penetrating peptide with a reversible thiol-reactive nitropyridyl (Npys) group. Cys(Npys)-(Arg)9 efficiently mediates the internalization and delivery of various "cargo" such as proteins and antibodies by forming reversible disulfide bonds with surface-exposed cysteine residues. Cys(Npys)-(Arg)9 endows TALEN proteins with cell-penetrating activity, enabling gene knockout in mammalian cells and protein transduction in wheat microspores. Cys(Npys)-(Arg)9 can be conjugated with antibodies to form cationized IgG for enhancing endosomal escape of oligonucleotides, or form siRNA delivery complexes. When the molar ratio of Cys(Npys)-(Arg)9 to loaded molecules is higher than 1:1, it exerts certain cytotoxic effects on cells. Cys(Npys)-(Arg)9 can be used in studies related to oral squamous cell carcinoma and HIV infection .
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Cat. No.: HY-W736950A
Research Areas:  

Others

H-L-Cys(MDNPE)-OH hydrochloride is a cysteine ​​derivative with a short peptide sequence attached to the thiol group of cysteine.
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