BTD probe-1
Based on 1 publication(s) in Google Scholar
BTD probe-1 is a benzothiazine-based chemoproteomic probe and selective protein S-sulfenic acid (Cys-SOH) labeling agent. BTD probe-1 labels protein S-sulfenic acids in vitro in cell and tissue samples, and in situ in intact cells, enabling detection or enrichment of modified proteins/peptides. BTD probe-1 exhibits no cytotoxicity in cells at concentrations ≤1 mM. BTD probe-1 enables global, site-specific mapping and quantification of cysteine S-sulfenylation in complex proteomes with lower input material.
For research use only. We do not sell to patients.
- Purity: 98.06%
- CAS No.: 2095485-22-4
- Formula: C13H13NO3S
- Molecular Weight:263.31
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) BTD probe-1
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Biological Activity
Under conditions such as oxidative stress, the thiol group (-SH) of cysteine residues in proteins may be oxidized to S-sulfinic acid group (-SOH). BTD probe-1 can selectively react with this specific oxidized form to label it.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2095485-22-4
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Appearance Solid
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Molecular Weight 263.31
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Formula C13H13NO3S
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Color White to off-white
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SMILES
O=C1CS(N(CCCC#C)C2=CC=CC=C12)(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : 100 mg/mL (379.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7978 mL | 18.9890 mL | 37.9780 mL | 94.9451 mL |
| 5 mM | 0.7596 mL | 3.7978 mL | 7.5956 mL | 18.9890 mL | |
| 10 mM | 0.3798 mL | 1.8989 mL | 3.7978 mL | 9.4945 mL | |
| 15 mM | 0.2532 mL | 1.2659 mL | 2.5319 mL | 6.3297 mL | |
| 20 mM | 0.1899 mL | 0.9495 mL | 1.8989 mL | 4.7473 mL | |
| 25 mM | 0.1519 mL | 0.7596 mL | 1.5191 mL | 3.7978 mL | |
| 30 mM | 0.1266 mL | 0.6330 mL | 1.2659 mL | 3.1648 mL | |
| 40 mM | 0.0949 mL | 0.4747 mL | 0.9495 mL | 2.3736 mL | |
| 50 mM | 0.0760 mL | 0.3798 mL | 0.7596 mL | 1.8989 mL | |
| 60 mM | 0.0633 mL | 0.3165 mL | 0.6330 mL | 1.5824 mL | |
| 80 mM | 0.0475 mL | 0.2374 mL | 0.4747 mL | 1.1868 mL | |
| 100 mM | 0.0380 mL | 0.1899 mL | 0.3798 mL | 0.9495 mL |
BTD probe-1 Related Classifications
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