2095485-22-4

BTD probe-1 Chemical Structure
2095485-22-4

Chemical Structure

BTD probe-1

  • CAS No.: 2095485-22-4
  • Formula:C13H13NO3S
  • Molecular Weight:263.31

InChIKey: GSSKUKMXWRNMFK-UHFFFAOYSA-N

SMILES: O=C1CS(N(CCCC#C)C2=CC=CC=C12)(=O)=O

Biological Activity: BTD probe-1 is a benzothiazine-based chemoproteomic probe and selective protein S-sulfenic acid (Cys-SOH) labeling agent. BTD probe-1 labels protein S-sulfenic acids in vitro in cell and tissue samples, and in situ in intact cells, enabling detection or enrichment of modified proteins/peptides. BTD probe-1 exhibits no cytotoxicity in cells at concentrations ≤1 mM. BTD probe-1 enables global, site-specific mapping and quantification of cysteine S-sulfenylation in complex proteomes with lower input material[1].

Cat. No. Product Name Purity Description Pricing
HY-D2186 		BTD probe-1 98.06% BTD probe-1 is a benzothiazine-based chemoproteomic probe and selective protein S-sulfenic acid (Cys-SOH) labeling agent. BTD probe-1 labels protein S-sulfenic acids in vitro in cell and tissue samples, and in situ in intact cells, enabling detection or enrichment of modified proteins/peptides. BTD probe-1 exhibits no cytotoxicity in cells at concentrations ≤1 mM. BTD probe-1 enables global, site-specific mapping and quantification of cysteine S-sulfenylation in complex proteomes with lower input material.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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