Taltrimide
Taltrimide (MY-117), a lipophilic derivative of Taurine (HY-B0351), strongly inhibits the sodium-independent binding of Taurine to synaptic membranes of brain, the effects on the binding of GABA being less pronounced. Taltrimide exhibits definitive anticonvulsive effects in experimental epilepsy models.
For research use only. We do not sell to patients.
- CAS No.: 81428-04-8
- Formula: C13H16N2O4S
- Molecular Weight:296.34
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 81428-04-8
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Appearance Solid
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Molecular Weight 296.34
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Formula C13H16N2O4S
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Color Light yellow to yellow
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SMILES
O=S(CCN(C(C1=C2C=CC=C1)=O)C2=O)(NC(C)C)=O
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Synonyms
MY-117
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Airaksinen EM, et, al. Biochemical and clinical studies on epileptic patients during two phase I trials with the novel anticonvulsant taltrimide. Epilepsy Res. 1987 Sep;1(5):308-11. [Content Brief]
[2]. Keränen T, et, al. Effects of taltrimide, an experimental taurine derivative, on photoconvulsive response in epileptic patients. Epilepsia. 1987 Mar-Apr;28(2):133-7. [Content Brief]
[3]. Kontro P, et, al. Effects of the anticonvulsant taurine derivative, taltrimide, on membrane transport and binding of GABA and taurine in the mouse cerebrum. Neuropharmacology. 1987 Jan;26(1):19-23. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)