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Cys modifier 1 (compound 7) is a cysteine-selective protein modifier for protein bioconjugation. A fluorescent carbonylacrylic derivative bearing nitrobenzofurazan (λex=465nm and λem539 nm)[1].

For research use only. We do not sell to patients.

Cys modifier 1 Chemical Structure

Cys modifier 1 Chemical Structure

CAS No. : 2374314-08-4

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 324 In-stock
Solution
10 mM * 1 mL in DMSO USD 324 In-stock
Solid
1 mg USD 175 In-stock
5 mg USD 386 In-stock
10 mg USD 617 In-stock
25 mg USD 1234 In-stock
50 mg USD 1970 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Cys modifier 1 Related Antibodies

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Description

Cys modifier 1 (compound 7) is a cysteine-selective protein modifier for protein bioconjugation. A fluorescent carbonylacrylic derivative bearing nitrobenzofurazan (λex=465nm and λem539 nm)[1].

Molecular Weight

381.34

Formula

C18H15N5O5
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=C(NCCNC1=CC=C([N+]([O-])=O)C2=NON=C21)/C=C/C(C3=CC=CC=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (131.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6223 mL 13.1117 mL 26.2233 mL
5 mM 0.5245 mL 2.6223 mL 5.2447 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.95%

COA (246 KB) HNMR (121 KB) RP-HPLC (169 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6223 mL 13.1117 mL 26.2233 mL 65.5583 mL
5 mM 0.5245 mL 2.6223 mL 5.2447 mL 13.1117 mL
10 mM 0.2622 mL 1.3112 mL 2.6223 mL 6.5558 mL
15 mM 0.1748 mL 0.8741 mL 1.7482 mL 4.3706 mL
20 mM 0.1311 mL 0.6556 mL 1.3112 mL 3.2779 mL
25 mM 0.1049 mL 0.5245 mL 1.0489 mL 2.6223 mL
30 mM 0.0874 mL 0.4371 mL 0.8741 mL 2.1853 mL
40 mM 0.0656 mL 0.3278 mL 0.6556 mL 1.6390 mL
50 mM 0.0524 mL 0.2622 mL 0.5245 mL 1.3112 mL
60 mM 0.0437 mL 0.2185 mL 0.4371 mL 1.0926 mL
80 mM 0.0328 mL 0.1639 mL 0.3278 mL 0.8195 mL
100 mM 0.0262 mL 0.1311 mL 0.2622 mL 0.6556 mL
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Cys modifier 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cys modifier 12374314-08-4Cys modifier1Cys modifier-1OthersInhibitorinhibitorinhibit

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