Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
59 Results for "
glycine site
" in MedChemExpress (MCE) Product Catalog:
Products (59)
59 Results for "glycine site" in MCE Product Catalog:
9
9 Publications Verification
Synonyms: (S)-2-Amino-3-phenylpropionic acid
4
Target:
Research Areas:
7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery .
4
4 Cited Publications
Synonyms: 7-CKA sodium salt
Target:
Research Areas:
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery .
2
2 Cited Publications
Cat. No.: HY-N0215S10
CAS No.: 439685-11-7
Synonyms: (S)-2-Amino-3-phenylpropionic acid-13C9
1
1 Cited Publications
Synonyms: Dimethylglycine; DMG; N-Methylsarcosine
1
1 Cited Publications
Cat. No.: HY-N0215S12
CAS No.: 56253-90-8
Synonyms: (S)-2-Amino-3-phenylpropionic acid-d5
1
Target:
Research Areas:
5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective and competitive antagonist of the glycine site on NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid reduces NMDA-induced neuron injury. 5,7-Dichlorokynurenic acid increases social interaction time, increases open arm exploration time, disinhibits suppressed conflict responding in rodent models. 5,7-Dichlorokynurenic acid exhibits anxiolytic-like activity in rodent models and supports exploration of glycine’s role in NMDA receptor-mediated synaptic transmission .
1
1 Cited Publications
Cat. No.: HY-N0215S1
CAS No.: 17942-32-4
Synonyms: (S)-2-Amino-3-phenylpropionic acid-d8
1
1 Cited Publications
Cat. No.: HY-N0215S8
CAS No.: 180268-82-0
Synonyms: (S)-2-Amino-3-phenylpropionic acid-13C6
1
1 Cited Publications
Cat. No.: HY-W001158
CAS No.: 2491-06-7
Synonyms: Dimethylglycine hydrochloride; DMG hydrochloride; N-Methylsarcosine hydrochloride
Research Areas:
1
1 Cited Publications
Cat. No.: HY-N0215S7
CAS No.: 136056-02-5
Synonyms: (S)-2-Amino-3-phenylpropionic acid-3-13C
1
1 Cited Publications
Synonyms: Dimethylglycine (Standard); DMG (Standard); N-Methylsarcosine (Standard)
1
1 Cited Publications
Cat. No.: HY-N0215S2
CAS No.: 81201-86-7
Synonyms: (S)-2-Amino-3-phenylpropionic acid-13C
Cat. No.: HY-W001158S
CAS No.: 347840-03-3
Synonyms: Dimethylglycine-d6 hydrochloride; DMG-d6 hydrochloride; N-Methylsarcosine-d6 hydrochloride
Cat. No.: HY-18698
CAS No.: 142326-59-8
Target:
Research Areas:
L-701324 is a potent, orally active NMDA receptor antagonist that antagonizes the activity of the NMDA receptor by blocking its glycine B binding site. L-701324 binds with high affinity to rat brain membranes (IC50=2 nM). L-701324 has antidepressant activity .
Target:
Target:
Research Areas:
CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor, with an IC50 of 6 nM. CGP 78608 hydrochloride acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC50 in the low nM range (26.3 nM). Anticonvulsant activity .
Cat. No.: HY-P3732
CAS No.: 332179-76-7
Target:
Research Areas:
L-689560 is a potent N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. L-689560 is widely used as a radiolabeled ligand in binding studies and used for study the roles of NMDA receptors in normal neurological processes as well as in diseases .
Cat. No.: HY-W014504
CAS No.: 343-65-7
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
