2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Gavestinel

Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects.

For research use only. We do not sell to patients.

Gavestinel Chemical Structure

Gavestinel Chemical Structure

CAS No. : 153436-22-7

Size Price Stock Quantity
5 mg USD 125 In-stock
10 mg USD 200 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Gavestinel:

Gavestinel Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects[1].

Molecular Weight

375.21

Formula

C18H12Cl2N2O3
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C(N1)=C(/C=C/C(NC2=CC=CC=C2)=O)C3=C1C=C(Cl)C=C3Cl)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (333.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6652 mL 13.3259 mL 26.6517 mL
5 mM 0.5330 mL 2.6652 mL 5.3303 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6652 mL 13.3259 mL 26.6517 mL 66.6294 mL
5 mM 0.5330 mL 2.6652 mL 5.3303 mL 13.3259 mL
10 mM 0.2665 mL 1.3326 mL 2.6652 mL 6.6629 mL
15 mM 0.1777 mL 0.8884 mL 1.7768 mL 4.4420 mL
20 mM 0.1333 mL 0.6663 mL 1.3326 mL 3.3315 mL
25 mM 0.1066 mL 0.5330 mL 1.0661 mL 2.6652 mL
30 mM 0.0888 mL 0.4442 mL 0.8884 mL 2.2210 mL
40 mM 0.0666 mL 0.3331 mL 0.6663 mL 1.6657 mL
50 mM 0.0533 mL 0.2665 mL 0.5330 mL 1.3326 mL
60 mM 0.0444 mL 0.2221 mL 0.4442 mL 1.1105 mL
80 mM 0.0333 mL 0.1666 mL 0.3331 mL 0.8329 mL
100 mM 0.0267 mL 0.1333 mL 0.2665 mL 0.6663 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Gavestinel Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gavestinel153436-22-7GV 150526GV150526GV-150526iGluRIonotropic glutamate receptorsneuroprotectant effectglycine siteNMDA receptorInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Gavestinel
Cat. No.:
HY-150138
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.