L-Phenylalanine-15N,d8
Based on 1 Customer Validation
L-Phenylalanine-15N,d8 is the deuterium and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca2+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.
For research use only. We do not sell to patients.
- Purity: 99.90%
- Formula: C9H3D815NO2
- Molecular Weight:174.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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NMDA Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 63-91-2
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Appearance Solid
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Molecular Weight 174.23
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Formula C9H3D815NO2
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Color White to off-white
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SMILES
[15NH2][C@](C([2H])([2H])C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])([2H])C(O)=O
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Synonyms
(S)-2-Amino-3-phenylpropionic acid-15N,d8
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 16.67 mg/mL (95.68 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O | 1 mM | 5.7395 mL | 28.6977 mL | 57.3954 mL | 143.4885 mL |
| 5 mM | 1.1479 mL | 5.7395 mL | 11.4791 mL | 28.6977 mL | |
| 10 mM | 0.5740 mL | 2.8698 mL | 5.7395 mL | 14.3488 mL | |
| 15 mM | 0.3826 mL | 1.9132 mL | 3.8264 mL | 9.5659 mL | |
| 20 mM | 0.2870 mL | 1.4349 mL | 2.8698 mL | 7.1744 mL | |
| 25 mM | 0.2296 mL | 1.1479 mL | 2.2958 mL | 5.7395 mL | |
| 30 mM | 0.1913 mL | 0.9566 mL | 1.9132 mL | 4.7829 mL | |
| 40 mM | 0.1435 mL | 0.7174 mL | 1.4349 mL | 3.5872 mL | |
| 50 mM | 0.1148 mL | 0.5740 mL | 1.1479 mL | 2.8698 mL | |
| 60 mM | 0.0957 mL | 0.4783 mL | 0.9566 mL | 2.3915 mL | |
| 80 mM | 0.0717 mL | 0.3587 mL | 0.7174 mL | 1.7936 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Phenylalanine-15N,d8 Related Classifications
HY-N0215S14 Related Classifications
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