1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. iGluR
  3. 7-Chlorokynurenic acid sodium salt

7-Chlorokynurenic acid sodium salt 

Cat. No.: HY-100811A Purity: 99.79%
Handling Instructions

7-Chlorokynurenic acid sodium salt is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex and also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM.

For research use only. We do not sell to patients.

7-Chlorokynurenic acid sodium salt Chemical Structure

7-Chlorokynurenic acid sodium salt Chemical Structure

CAS No. : 1263094-00-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 77 In-stock
Estimated Time of Arrival: December 31
10 mg USD 70 In-stock
Estimated Time of Arrival: December 31
50 mg USD 290 In-stock
Estimated Time of Arrival: December 31
100 mg USD 520 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Other Forms of 7-Chlorokynurenic acid sodium salt:

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Description

7-Chlorokynurenic acid sodium salt is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex and also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM.

IC50 & Target

N-methyl-D-aspartate receptor[1]
Ki: 0.59 μM (reuptake of glutamate)[1]

Storage

4°C, stored under nitrogen

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (203.59 mM; Need ultrasonic)

DMSO : ≥ 33.67 mg/mL (137.10 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0718 mL 20.3591 mL 40.7183 mL
5 mM 0.8144 mL 4.0718 mL 8.1437 mL
10 mM 0.4072 mL 2.0359 mL 4.0718 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.67 mg/mL (2.73 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 0.67 mg/mL (2.73 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 0.67 mg/mL (2.73 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

245.59

Formula

C₁₀H₅ClNNaO₃

CAS No.

1263094-00-3

SMILES

O=C(C1=NC2=CC(Cl)=CC=C2C(O)=C1)[O-].[Na+]

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
7-Chlorokynurenic acid sodium salt
Cat. No.:
HY-100811A
Quantity:

7-Chlorokynurenic acid sodium salt

Cat. No.: HY-100811A