1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. iGluR
    Potassium Channel
  3. Ifenprodil tartrate

Ifenprodil tartrate 

Cat. No.: HY-12882A Purity: 99.58%
Handling Instructions

Ifenprodil tartrate is a typical noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM). Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has the potential to be a cerebral vasodilator.

For research use only. We do not sell to patients.

Ifenprodil tartrate Chemical Structure

Ifenprodil tartrate Chemical Structure

CAS No. : 23210-58-4

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Solution
10 mM * 1 mL in DMSO USD 101 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 101 In-stock
Estimated Time of Arrival: December 31
Solid
50 mg USD 92 In-stock
Estimated Time of Arrival: December 31
100 mg USD 158 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Ifenprodil tartrate:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Ifenprodil tartrate

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Ifenprodil tartrate is a typical noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM)[1]. Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has the potential to be a cerebral vasodilator[2].

IC50 & Target

IC50: 0.34 μM (NR1A/NR2B receptor); 146 μM (NR1A/NR2A receptor)[1]

In Vitro

G protein-activated inwardly rectifying K+ channels (GIRK)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

400.49

Formula

C25H33NO8

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 500 mg/mL (1248.47 mM)

H2O : 5 mg/mL (12.48 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4969 mL 12.4847 mL 24.9694 mL
5 mM 0.4994 mL 2.4969 mL 4.9939 mL
10 mM 0.2497 mL 1.2485 mL 2.4969 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  0.5% CMC-Na/saline water

    Solubility: 12.22 mg/mL (30.51 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  1% DMSO   99% saline

    Solubility: ≥ 1 mg/mL (2.50 mM); Clear solution

*All of the co-solvents are available by MCE.
References

Purity: 99.58%

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Product Name:
Ifenprodil tartrate
Cat. No.:
HY-12882A
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