Kynurenic acid (Standard)
Based on 1 Customer Validation
Kynurenic acid (Standard) is the analytical standard of Kynurenic acid. This product is intended for research and analytical applications. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8.
For research use only. We do not sell to patients.
- Purity: 98.87%
- CAS No.: 492-27-3
- Formula: C10H7NO3
- Molecular Weight:189.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 492-27-3
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Appearance Solid
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Molecular Weight 189.17
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Formula C10H7NO3
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Color Off-white to light yellow
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SMILES
O=C(C1=NC2=CC=CC=C2C(O)=C1)O
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Synonyms
Quinurenic acid (Standard)
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Structure Classification
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Initial Source
Human Blood, Cerebrospinal Fluid (CSF), Feces, Urine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang J, et al. Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J Biol Chem. 2006 Aug 4;281(31):22021-8. [Content Brief]
[2]. Albuquerque EX, et al. Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: facts and challenges. Biochem Pharmacol. 2013 Apr 15;85(8):1027-32. [Content Brief]
[3]. Małaczewska J, et al. Effect of oral administration of kynurenic acid on the activity of the peripheral blood leukocytes in mice. Cent Eur J Immunol. 2014;39(1):6-13. [Content Brief]
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