1. Membrane Transporter/Ion Channel
  2. EAAT2
  3. WAY-213613

WAY-213613 

Cat. No.: HY-107523 Purity: >99.0%
Handling Instructions

WAY-213613 is a potent, selective human EAAT2 inhibitor (IC50, 85 nM), exhibits 59- and 45-fold selectivity over human EAAT1 and EAAT3. Inhibits glutamate uptake in rat cortical synaptosomes.

For research use only. We do not sell to patients.

WAY-213613 Chemical Structure

WAY-213613 Chemical Structure

CAS No. : 868359-05-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 231 In-stock
Estimated Time of Arrival: December 31
5 mg USD 210 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

WAY-213613 is a potent, selective human EAAT2 inhibitor (IC50, 85 nM), exhibits 59- and 45-fold selectivity over human EAAT1 and EAAT3. Inhibits glutamate uptake in rat cortical synaptosomes[1].

IC50 & Target

IC50: 85 nM (Human EAAT2), 3.8 μM (Human EAAT3), 5 μM (Human EAAT1)[1]

In Vitro

WAY-213613 exhibits IC50s of 5 and 3.8 μM for EAAT1 and EAAT3, respectively[1].

Molecular Weight

415.19

Formula

C₁₆H₁₃BrF₂N₂O₄

CAS No.

868359-05-1

SMILES

BrC(C=C(F)C(F)=C1)=C1OC2=CC=C(NC(C[[email protected]](N)C(O)=O)=O)C=C2

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >99.0%

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WAY-213613
Cat. No.:
HY-107523
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