L-Phenylalanine-13C6
Based on 1 publication(s) in Google Scholar
L-Phenylalanine-13C6 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.
For research use only. We do not sell to patients.
- Purity: 99.87%
- CAS No.: 180268-82-0
- Formula: C313C6H11NO2
- Molecular Weight:171.15
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) L-Phenylalanine-13C6
MoreAll Calcium Channel Isoforms
MoreAll iGluR Isoforms
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Biological Activity
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NMDA Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 180268-82-0
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Unlabeled Cas 63-91-2
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Appearance Solid
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Molecular Weight 171.15
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Formula C313C6H11NO2
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Color White to off-white
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SMILES
OC([C@@H](N)C[13C]1=[13CH][13CH]=[13CH][13CH]=[13CH]1)=O
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Synonyms
(S)-2-Amino-3-phenylpropionic acid-13C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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J Agric Food Chem
Role of Phenylalanine in the Formation of Parent and Oxygenated Polycyclic Aromatic Hydrocarbons in Baking Systems. [Abstract]2025 Jul 30;73(30):19013-19025. PMID: 40680198
Solvent & Solubility
H2O : 6.67 mg/mL (38.97 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.8428 mL | 29.2141 mL | 58.4283 mL | 146.0707 mL |
| 5 mM | 1.1686 mL | 5.8428 mL | 11.6857 mL | 29.2141 mL | |
| 10 mM | 0.5843 mL | 2.9214 mL | 5.8428 mL | 14.6071 mL | |
| 15 mM | 0.3895 mL | 1.9476 mL | 3.8952 mL | 9.7380 mL | |
| 20 mM | 0.2921 mL | 1.4607 mL | 2.9214 mL | 7.3035 mL | |
| 25 mM | 0.2337 mL | 1.1686 mL | 2.3371 mL | 5.8428 mL | |
| 30 mM | 0.1948 mL | 0.9738 mL | 1.9476 mL | 4.8690 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.