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glycoside derivative

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Derivative (7) Amino Acid Derivatives (1) Antibiotic (1) Bacterial (1) Biochemical Assay Reagents (3) Drug Intermediate (1) Drug Metabolite (1) Environmental Pollutants (1) Glycosidase (1) HBV (1) Herbicide (1) IKK (1) Isotope-Labeled Compounds (1) NF-κB (1) Nuclear Hormone Receptor 4A/NR4A (1) Sialyltransferase (1) TNF Receptor (1) Virus Protease (3)
By Research Areas:	Cancer (7) Infection (6) Inflammation/Immunology (3) Metabolic Disease (1) Neurological Disease (2)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Drug Derivative

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W039897

Methyl α-D-mannopyranoside 1 Publications Verification α-Methyl-D-mannoside	Environmental Pollutants Bacterial	Infection
Methyl α-D-mannopyranoside (α-Methyl-D-mannoside) is a methyl glycoside derivative and conformational stabilizer of α-D-mannopyranose. The glycosidic bond conformation of Methyl α-D-mannopyranoside is significantly affected by the environment. In aqueous solution, Methyl α-D-mannopyranoside stabilizes into a trans conformation via intermolecular hydrogen bonds; in the gas phase, however, steric interactions drive Methyl α-D-mannopyranoside to prefer a clockwise gauche conformation. Methyl α-D-mannopyranoside also serves as a major component of secondary cell wall polymers in some bacteria and an active precursor site for virus-targeted glycoproteins. Methyl α-D-mannopyranoside acts as an acceptor substrate for alternansucrase, mediating the transfer of D-glucopyranosyl groups to generate a variety of glycosylated oligosaccharide products, with methyl α-D-glucopyranosyl-(1→6)-α-D-mannopyranoside as the main component. Methyl α-D-mannopyranoside is applicable to studies on bacterial pathogenic mechanisms associated with mannose-specific fimbrial lectins .

HY-34666

(4S)-4-Hydroxy-D-proline	Biochemical Assay Reagents Amino Acid Derivatives	Others
(4S)-4-Hydroxy-D-proline is a D-proline derivative and aglycon core for synthesis of cell wall O-glycans of the green alga Chlamydomonas reinhardtii .

HY-N7905

Myricetin 3'-glucoside	Others	Inflammation/Immunology
Myricetin 3'-glucoside is a glycoside derivative of quercetin. Myricetin 3'-glucoside significantly prevents ethanol-induced hepatotoxicity by reducing hepatic transaminase activity and inflammatory response in HepG2 cells. Myricetin 3'-glucoside has a certain protective effect on alcohol-induced liver injury .

HY-116284

Methyl β-D-glucopyranoside Methyl β-D-glucoside	Drug Intermediate	Others
Methyl β-D-glucopyranoside (Methyl β-D-glucoside) is a model glycosyl acceptor for enzymatic glycosylation reactions. Methyl β-D-glucopyranoside participates in glycoside synthesis and can react with acyl donors such as caffeic acid esters under the catalysis of specific enzymes (such as Lipozyme TL IM) to achieve acylation modification. Methyl β-D-glucopyranoside can generate biologically active derivatives (such as 6-O-caffeoyl glucoside). Methyl β-D-glucopyranoside can be used in organic synthesis and biocatalysis research, especially the efficient enzymatic preparation of medicinal glycosides (such as Robustaside B (HY-N2720), 6-O-caffeoyl salidroside) .

HY-N10407

Quercetin 3-O-rutinoside-7-O-glucoside	Drug Derivative	Others
Quercetin 3-O-rutinoside-7-O-glucoside is a flavonol glycoside and a derivative of Quercetin (HY-18085). Quercetin 3-O-rutinoside-7-O-glucoside can be isolated from the leaves and fruits of Korean Morus alba L. as well as the leaves of Hemerocallis fulva. Quercetin 3-O-rutinoside-7-O-glucoside inhibits lipid peroxidation in large unilamellar vesicles in vitro. Quercetin 3-O-rutinoside-7-O-glucoside possesses antioxidant activity .

HY-N5086

Picroside IV	HBV	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Picroside IV is an iridoid glycoside found in the underground parts of Picrorhiza scrophulariiflora. Picroside IV is a derivative of Catalpol (HY-N0820) . Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-W142618

D-Glucal	Biochemical Assay Reagents	Others
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

HY-156752

Cyclosiversioside F 16,25-diacetate	Drug Metabolite	Others
Cyclosiversioside F 16,25-diacetate (Compound 6), a glycoside, is an alkaline hydrolysis product of Acetyl Derivative (Compound 2) .

HY-N7889

Syringetin-3-O-rutinoside	Others	Others
Syringetin-3-O-rutinoside is an antioxidant compound . Syringetin-3-O-rutinoside can be used for the synthesis of syringetin-O-glycoside derivatives .

HY-151581

HCVcc-IN-1	Virus Protease	Infection
HCVcc-IN-1 is a benzothiazole-2-thiophene S-glycoside derivative with low toxic and antiviral activity .

HY-112944A

CMP-SiaNAz sodium CMP-NeuNAz sodium	Sialyltransferase	Infection
CMP-SiaNAz (CMP-NeuNAz) sodium is a sialic acid nucleotide sugar derivative. CMP-SiaNAz sodium is integrated into the glycosidic chain through the action of STs in the Golgi apparatus, forming SiaNAz substances. CMP-SiaNAz sodium can serve as a substrate for bacterial-derived sialic acid transferases and is used for chemical enzymatic labeling and imaging of cell surface glycosides .

HY-N16574

Hyperwightin C	Others	Others
Hyperwightin C is a benzophenone glycoside. Hyperwightin C has not shown any significant neuroprotective effect .

HY-N1527

Quinovic acid 3-O-α-L-rhamnopyranoside Quinovic acid 3-O-α-L-rhamnoside	Others	Others
Quinovic acid 3-O-α-L-rhamnopyranoside (Quinovic acid 3-O-α-L-rhamnoside) is glycoside derivative. Quinovic acid 3-O-α-L-rhamnopyranoside can be isolated from the root bark of Guettarda angelica .

HY-N16498

Kaempferol 3-rungioside	Drug Derivative	Others
Kaempferol 3-rungioside is a glycoside derivative of Kaempferol (HY-14590) .

HY-131486

Digoxigenin bisdigitoxoside	Nuclear Hormone Receptor 4A/NR4A	Cancer
Digoxigenin bisdigitoxoside is an anticancer agent and an active derivative of cardiac glycosides. Cardiac glycosides exert their apoptotic effects through the Nur77-dependent apoptotic pathway. Digoxigenin bisdigitoxoside is cytotoxic .

HY-126422

cis-Tiliroside	Others	Cancer
cis-Tiliroside, a kaempferol derivative, is a flavonoid glycoside. cis-Tiliroside exhibits better cytotoxic activity than trans-Tiliroside in A549 cell line .

HY-151588

Anticancer agent 90	Virus Protease	Cancer
Anticancer agent 90 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity. Anticancer agent 90 has high inhibition against the two cell line from ovarian cancer (OVCAR-4), renal cancer (A498) .

HY-151592

Anticancer agent 91	Antibiotic	Cancer
Anticancer agent 91 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor and antiviral activity. Anticancer agent 91 has high inhibition against the two cell line from CNS cancer (SF-539 and SNB-75) .

HY-151587

Anticancer agent 89	Others	Cancer
Anticancer agent 89 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity, has high inhibition against the three cell line from ovarian cancer (OVCAR-4), renal cancer (A498), and melanoma (SK-MEL-5) .

HY-151589

HCVcc-IN-2	Virus Protease	Infection Cancer
HCVcc-IN-2 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor and antiviral activity. HCVcc-IN-2 has high inhibition against the three cell line from CNS cancer (SF-539 and SNB-75), colon cancer (HCT-116), and renal cancer (A498) .

HY-126232

Verproside	NF-κB TNF Receptor IKK	Infection Inflammation/Immunology
Verproside, a catalpol derivative iridoid glycoside isolated from the genus Pseudolysimachion, represses TNF-α -induced MUC5AC expression by inhibiting NF-κB activation via the IKK/IκB signaling cascade. Verproside has potent anti-inflammatory, antioxidant, antinociceptive and anti-asthmatic activities. Verproside has the potential for the study of chronic obstructive pulmonary disease (COPD) .

HY-W755679

Digitoxigenin-21,23,23-d3 Cerberigenin-d₃; Echujetin-d₃	Isotope-Labeled Compounds Biochemical Assay Reagents	Others
Digitoxigenin-21,23,23-d₃ (Cerberigenin-d₃; Echujetin-d₃) is the deuterium labeled Digitoxigenin (HY-B2151). Digitoxigenin is a steroid derivative commonly found in various plants, especially the foxglove plant (Digitalis purpurea). Digitoxigenin has unique chemical properties that make it an important precursor for the synthesis of cardiac glycosides, a group of drugs used to improve heart failure and certain types of arrhythmias. It works by inhibiting the sodium potassium ATPase pump, thereby increasing the force and efficiency of cardiac contractions.

HY-N19726

Capsianoside IV	Drug Derivative	Others
Capsianoside IV is a monomeric acyclic diterpenoid glycoside and geranyl linalool derivative, which can be isolated from the fruits of Capsicum annuum var. grossum (bell pepper) .

HY-N18350

26-Degluco-torvoside H	Glycosidase Drug Derivative	Others
26-Degluco-torvoside H (Compound 4) is a Furostanol glycoside derivative. 26-Degluco-torvoside H forms via hydrolysis of Torvoside H by β-glucosidase from Solanum torvum leaves .

HY-N20621

Subproside V	Others	Others
Subproside V is an oleanene glycoside found in the dried roots of Sophora subprostrata (Leguminosae). Glycosides are compounds formed by linking a sugar or sugar derivative to another non-sugar substance through the terminal carbon atom of the sugar; they are also known as sugar ligands. Glycoside compounds typically possess anti-inflammatory, anti-infective, anti-cancer, and antioxidant properties, playing a variety of important roles in organisms .

HY-N17531

4-(β-D-Glucopyranosyloxy)benzenepropanoic acid	Drug Derivative	Others
4-(β-D-Glucopyranosyloxy) benzenepropanoic acid is a phenolic acid glycoside natural product, which has an O-β-D-glucoside structure formed by a phenylpropanoic acid derivative and glucose .

HY-N18716

Senna leaf extract	Others	Others
Senna Leaf Extract is the main raw material of Cassia angustifolia Vahl. Its main active ingredients are Sennoside A and B, and contain rhein, aloe-emodin, chrysophanol and other anthraquinones Derivatives and other glycosides.

HY-N18680

Melissa officinalis extract	Others	Neurological Disease
Melissa officinalis extract is rich in various bioactive compounds, such as citronellol, geraniol, glycosides, caffeic acid derivatives, flavonoids, and triterpenoids. Melissa officinalis extract can be used in research on conditions such as nervous tension, anxiety, insomnia, and menstrual disorders.

HY-N17450

3′-O-[(2S)-2-Methylbutanoyl]henryoside	Drug Derivative	Others
3′-O-Henryoside (Compound 3) is a glycoside found in the leaves of Viburnum plicatum Thunb. var. tomentosum Miq, and is a (2S)-2-methylbutyryl derivative of Henryoside (HY-N4054) .

HY-W750858

DIBOA-Glucoside	Drug Derivative Herbicide	Others
DIBOA-Glucoside is a glycoside derivative that can be found in cereal crops like rye, wheat, and maize. DIBOA-Glucoside is a stable, less toxic glucoside form of DIBOA. DIBOA-Glucoside, upon pest or pathogen attack, is hydrolyzed by an enzyme, releasing the toxic aglycone DIBOA and glucose, thereby deterring insects and suppressing weeds through an allelopathic effect .

Cat. No.	Product Name

HY-L021M

Natural Product and Natural Product-Like Compound Library	5,019 compounds
From the discovery of traditional Chinese medicine to modern antibiotics, natural products have played an important role in the drug development process. A review of all FDA-approved drugs shows that natural products and natural product-like compounds account for more than one-third of all approved drugs. Nearly half of that came from mammals, a quarter from microbes, and a quarter from plants. Over time, the proportion of microbial natural products and natural product derivatives in approved drugs has increased. Natural products have natural advantages in drug development and can be used as lead compounds in drug discovery for drug identification and mechanism research. MCE provides a unique collection of 5,019 natural compounds and natural product-like compounds that contain saccharides and glycosides, phenylpropanoids, quinones, flavonoids, terpenoids and glycosides, steroids, alkaloid, phenols, acids and aldehydes. Natural product and natural product-like compounds library is a useful tool for drug discovery that can be used for high-throughput screening (HTS) and high-content screening (HCS).

Natural Product and Natural Product-Like Compound Library

5,019 compounds

From the discovery of traditional Chinese medicine to modern antibiotics, natural products have played an important role in the drug development process. A review of all FDA-approved drugs shows that natural products and natural product-like compounds account for more than one-third of all approved drugs. Nearly half of that came from mammals, a quarter from microbes, and a quarter from plants. Over time, the proportion of microbial natural products and natural product derivatives in approved drugs has increased. Natural products have natural advantages in drug development and can be used as lead compounds in drug discovery for drug identification and mechanism research.

MCE provides a unique collection of 5,019 natural compounds and natural product-like compounds that contain saccharides and glycosides, phenylpropanoids, quinones, flavonoids, terpenoids and glycosides, steroids, alkaloid, phenols, acids and aldehydes. Natural product and natural product-like compounds library is a useful tool for drug discovery that can be used for high-throughput screening (HTS) and high-content screening (HCS).

Cat. No.	Product Name	Type

HY-34666

(4S)-4-Hydroxy-D-proline	Biochemical Assay Reagents
(4S)-4-Hydroxy-D-proline is a D-proline derivative and aglycon core for synthesis of cell wall O-glycans of the green alga Chlamydomonas reinhardtii .

HY-W142618

D-Glucal	Biochemical Assay Reagents
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

D-Glucal

Biochemical Assay Reagents

D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7905

Myricetin 3'-glucoside	Structural Classification Flavonols Flavonoids Myrtaceae Syzygium malaccense (L.) Merr. et Perry Plants Source Classification	Others
Myricetin 3'-glucoside is a glycoside derivative of quercetin. Myricetin 3'-glucoside significantly prevents ethanol-induced hepatotoxicity by reducing hepatic transaminase activity and inflammatory response in HepG2 cells. Myricetin 3'-glucoside has a certain protective effect on alcohol-induced liver injury .

HY-N5086

Picroside IV	Neurological Disease Classification of Application Fields Metabolic Disease Plants Monophenols Iridoids Terpenoids Phenols Scrophulariaceae Picrorhiza scrophulariiflora Pennell Inflammation/Immunology Disease Research Fields Source Classification	HBV
Picroside IV is an iridoid glycoside found in the underground parts of Picrorhiza scrophulariiflora. Picroside IV is a derivative of Catalpol (HY-N0820) . Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-N7889

Syringetin-3-O-rutinoside	Flavonols Flavonoids Classification of Application Fields Larix sibirica Ledeb. Pinaceae Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Others
Syringetin-3-O-rutinoside is an antioxidant compound . Syringetin-3-O-rutinoside can be used for the synthesis of syringetin-O-glycoside derivatives .

HY-N16574

Hyperwightin C	Structural Classification Hypericum wightianum Wall. ex Wight & Arn. Other Phenylpropanoids Hypericaceae Phenylpropanoids Plants Source Classification	Others
Hyperwightin C is a benzophenone glycoside. Hyperwightin C has not shown any significant neuroprotective effect .

HY-N1527

Quinovic acid 3-O-α-L-rhamnopyranoside Quinovic acid 3-O-α-L-rhamnoside	Triterpenes Guettarda angelica Mart. ex Müll.Arg. Terpenoids Rubiaceae Plants Umbelliferae Echinacea angustifolia DC. Source Classification	Others
Quinovic acid 3-O-α-L-rhamnopyranoside (Quinovic acid 3-O-α-L-rhamnoside) is glycoside derivative. Quinovic acid 3-O-α-L-rhamnopyranoside can be isolated from the root bark of Guettarda angelica .

HY-N16498

Kaempferol 3-rungioside	Structural Classification Flavonoids Acanthaceae Flavones Salvia digitaloides Diels Plants Source Classification	Drug Derivative
Kaempferol 3-rungioside is a glycoside derivative of Kaempferol (HY-14590) .

HY-126422

cis-Tiliroside	Flavonols Flavonoids other families Classification of Application Fields Phenols Polyphenols Plants Disease Research Fields Cancer Source Classification	Others
cis-Tiliroside, a kaempferol derivative, is a flavonoid glycoside. cis-Tiliroside exhibits better cytotoxic activity than trans-Tiliroside in A549 cell line .

HY-126232

Verproside	Plantaginaceae Infection Iridoids Veronica officinalis L. Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification	NF-κB TNF Receptor IKK
Verproside, a catalpol derivative iridoid glycoside isolated from the genus Pseudolysimachion, represses TNF-α -induced MUC5AC expression by inhibiting NF-κB activation via the IKK/IκB signaling cascade. Verproside has potent anti-inflammatory, antioxidant, antinociceptive and anti-asthmatic activities. Verproside has the potential for the study of chronic obstructive pulmonary disease (COPD) .

HY-N19726

Capsianoside IV	Structural Classification Capsicum annuum L. Terpenoids Diterpenoids Solanaceae Plants Source Classification	Drug Derivative
Capsianoside IV is a monomeric acyclic diterpenoid glycoside and geranyl linalool derivative, which can be isolated from the fruits of Capsicum annuum var. grossum (bell pepper) .

HY-N18350

26-Degluco-torvoside H	Triterpenes Structural Classification Terpenoids Solanum torvum Swartz Solanaceae Plants Source Classification	Glycosidase Drug Derivative
26-Degluco-torvoside H (Compound 4) is a Furostanol glycoside derivative. 26-Degluco-torvoside H forms via hydrolysis of Torvoside H by β-glucosidase from Solanum torvum leaves .

HY-N20621

Subproside V	Triterpenes Structural Classification Leguminosae Terpenoids Sophora tonkinensis Gagnep. Plants Source Classification	Others
Subproside V is an oleanene glycoside found in the dried roots of Sophora subprostrata (Leguminosae). Glycosides are compounds formed by linking a sugar or sugar derivative to another non-sugar substance through the terminal carbon atom of the sugar; they are also known as sugar ligands. Glycoside compounds typically possess anti-inflammatory, anti-infective, anti-cancer, and antioxidant properties, playing a variety of important roles in organisms .

HY-N17531

4-(β-D-Glucopyranosyloxy)benzenepropanoic acid	Structural Classification Solanum lycopersicum L. Solanaceae Plants Saccharides Monosaccharides Source Classification	Drug Derivative
4-(β-D-Glucopyranosyloxy) benzenepropanoic acid is a phenolic acid glycoside natural product, which has an O-β-D-glucoside structure formed by a phenylpropanoic acid derivative and glucose .

HY-N18716

Senna leaf extract	Structural Classification Extract	Others
Senna Leaf Extract is the main raw material of Cassia angustifolia Vahl. Its main active ingredients are Sennoside A and B, and contain rhein, aloe-emodin, chrysophanol and other anthraquinones Derivatives and other glycosides.

HY-N18680

Melissa officinalis extract	Structural Classification Extract	Others
Melissa officinalis extract is rich in various bioactive compounds, such as citronellol, geraniol, glycosides, caffeic acid derivatives, flavonoids, and triterpenoids. Melissa officinalis extract can be used in research on conditions such as nervous tension, anxiety, insomnia, and menstrual disorders.

HY-N17450

3′-O-[(2S)-2-Methylbutanoyl]henryoside	Structural Classification Monophenols Viburnaceae Phenols Plants Viburnum plicatum Thunb. Source Classification	Drug Derivative
3′-O-Henryoside (Compound 3) is a glycoside found in the leaves of Viburnum plicatum Thunb. var. tomentosum Miq, and is a (2S)-2-methylbutyryl derivative of Henryoside (HY-N4054) .

HY-W750858

DIBOA-Glucoside	Blepharis edulis (Forssk.) Pers. Structural Classification Alkaloids Acanthaceae Other Alkaloids Plants Source Classification	Drug Derivative Herbicide
DIBOA-Glucoside is a glycoside derivative that can be found in cereal crops like rye, wheat, and maize. DIBOA-Glucoside is a stable, less toxic glucoside form of DIBOA. DIBOA-Glucoside, upon pest or pathogen attack, is hydrolyzed by an enzyme, releasing the toxic aglycone DIBOA and glucose, thereby deterring insects and suppressing weeds through an allelopathic effect .

Cat. No.	Product Name	Chemical Structure

HY-W755679

Digitoxigenin-21,23,23-d3

Digitoxigenin-21,23,23-d₃ (Cerberigenin-d₃; Echujetin-d₃) is the deuterium labeled Digitoxigenin (HY-B2151). Digitoxigenin is a steroid derivative commonly found in various plants, especially the foxglove plant (Digitalis purpurea). Digitoxigenin has unique chemical properties that make it an important precursor for the synthesis of cardiac glycosides, a group of drugs used to improve heart failure and certain types of arrhythmias. It works by inhibiting the sodium potassium ATPase pump, thereby increasing the force and efficiency of cardiac contractions.

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glycoside derivative

Inhibitors & Agonists

Screening Libraries

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NaturalProducts

Isotope-Labeled Compounds

Natural
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