CMP-SiaNAz sodium (Synonyms: CMP-NeuNAz sodium)

Cat. No.: HY-112944A Purity: 93.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

CMP-SiaNAz (CMP-NeuNAz) sodium is a sialic acid nucleotide sugar derivative. CMP-SiaNAz sodium is integrated into the glycosidic chain through the action of STs in the Golgi apparatus, forming SiaNAz substances. CMP-SiaNAz sodium can serve as a substrate for bacterial-derived sialic acid transferases and is used for chemical enzymatic labeling and imaging of cell surface glycosides.

For research use only. We do not sell to patients.

CMP-SiaNAz sodium Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Description

Molecular Weight

699.43

Formula

C₂₀H₂₈N₇Na₂O₁₆P

Appearance

Solid

Color

White to off-white

SMILES

NC(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(O[C@@]3(C(O[Na])=O)C[C@H](O)[C@@H](NC(CN=[N+]=[N-])=O)[C@H]([C@H](O)[C@H](O)CO)O3)(O[Na])=O)O2)=NC1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (142.97 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.4297 mL	7.1487 mL	14.2974 mL
5 mM	0.2859 mL	1.4297 mL	2.8595 mL
10 mM	0.1430 mL	0.7149 mL	1.4297 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 93.0%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (252 KB) HNMR (196 KB) LCMS (82 KB)

Handling Instructions (2659 KB)

References

[1]. Hong S, et al. Bacterial glycosyltransferase-mediated cell-surface chemoenzymatic glycan modification. Nat Commun. 2019 Apr 17;10(1):1799. [Content Brief]

[2]. Martinez-Duncker I, et al. Towards in vivo imaging of cancer sialylation. Int J Mol Imaging. 2011;2011:283497. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.4297 mL	7.1487 mL	14.2974 mL	35.7434 mL
	5 mM	0.2859 mL	1.4297 mL	2.8595 mL	7.1487 mL
	10 mM	0.1430 mL	0.7149 mL	1.4297 mL	3.5743 mL
	15 mM	0.0953 mL	0.4766 mL	0.9532 mL	2.3829 mL
	20 mM	0.0715 mL	0.3574 mL	0.7149 mL	1.7872 mL
	25 mM	0.0572 mL	0.2859 mL	0.5719 mL	1.4297 mL
	30 mM	0.0477 mL	0.2383 mL	0.4766 mL	1.1914 mL
	40 mM	0.0357 mL	0.1787 mL	0.3574 mL	0.8936 mL
	50 mM	0.0286 mL	0.1430 mL	0.2859 mL	0.7149 mL
	60 mM	0.0238 mL	0.1191 mL	0.2383 mL	0.5957 mL
	80 mM	0.0179 mL	0.0894 mL	0.1787 mL	0.4468 mL
	100 mM	0.0143 mL	0.0715 mL	0.1430 mL	0.3574 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

CMP-SiaNAz sodium Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CMP-SiaNAzCMP-NeuNAzSialyltransferasesialic acidchemoenzymatic labelingbacterial sialyltransferasebioorthogonal chemistryglycan imaginginfluenza virus receptorhost-pathogen interactionInhibitorinhibitorinhibit

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CMP-SiaNAz sodium (Synonyms: CMP-NeuNAz sodium)

CMP-SiaNAz sodium Related Antibodies

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